Path - Soft Tissue Flashcards
1
Q
where do soft tissue tumors normally arise
A
in the extremities, especially the thigh
2
Q
what genes/syndromes are associated with soft tissue tumors
A
NF1, gardner, Li-Fraumeni, Osler-Weber-Rendu
3
Q
what environmental exposures are associated with soft tissue tumors
A
radiation, burns, toxins
4
Q
what cytogenic abnormality is associated with liposarcoma - myxoid and round cell type
A
t(12;16)(q13;p11)
5
Q
what cytogenic abnormality is associated with synovial sarcoma
A
t(x;18)(p11;q11)
6
Q
what cytogenic abnormality is associated with rhabdomyosarcoma
A
t(2;13)(q35;q14)
7
Q
what is the most common soft tissue tumor of adults
A
lipoma
8
Q
where do fibrosarcomas occur
A
thigh or trunk
9
Q
histological hallmark of fibrosarcoma
A
strikingly uniform, spindled cells arranged in herringbone fascicles
