Path - Peripheral Nerve Sheath Tumors

Question 1

NF-1 is associated with what CNS lesions and skin manifestations

Answer 1

optic pathway glioma

brainstem glioma

skin: cafe au lait spots

Question 2

NF-2 is associated with what CNS lesion

Answer 2

bilateral acoustic schwannomas (affecting CN 8)

Question 3

retinoblastoma is associated with what CNS lesion

Answer 3

pineoblastoma

Question 4

von hippel-lindau syndrmoe is associated with what CNS lesion

Answer 4

hermangioblastoma of cerebellum/spine

Question 5

tuberous sclerosis is associated with what CNS lesion

Answer 5

subependymal giant cell astrocytoma

Question 6

nevoid basal cell carcinoma (gorlin) syndrome is associated with what CNS lesion

Answer 6

medulloblastoma

Question 7

lhermitte-duclos/cowden syndrome is associated with what CNS lesion

Answer 7

dysplastic gangliocytoma of the cerebellum

Question 8

Li-fraumeni syndrome is associated with what CNS lesion

Answer 8

malignant glioma

Question 9

S100+ marker is associated with what tumor

Answer 9

peripheral nerve sheath tumors