path recall April 2016 - formatted Flashcards

1
Q
  1. Young woman with fever and neck mass isoechoic to muscle on ultrasound and anterior to the carotid sheath - Repeat question.

a) Lymphoma
b) Metastatic papillary thyroid
c)
d)
e)

A

a) Lymphoma

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2
Q
  1. man / woman mildly elevated ESR fusiform AAA and perianeurysmal soft tissue swelling (These were two separate questions, one middle aged man and the other 40 year old woman)

a) Saccular mycotic
b) Inflammatory
c) Pseudoaneurysm
d) Takayasu
e) PAN

A

b) Inflammatory – if male

d) Takayasu – if female

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3
Q
  1. Man involved in high speed accident undergoes CT which demonstrates 2mm, well defined outpouching from thoracic aorta anteroinferior wall immediately distal to left SC origin

a) Ductus diverticulum
b) Traumatic aortic injury
c) Dissection
d) Transection

A

b) Traumatic aortic injury could be ductus diverticulum?? um
Traumatic pseudoaneurysm:- inferior aortic isthmus- acute angle- no calc. Surrounding stranding
Ductus- anteromedial isthmus- obtuse angle- calcium : very helpful clue

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4
Q

Location of aortic injury

A

Location aortic isthmus: 90%ascending aorta: 5%diaphragmatic hiatus: 5%

Aortic isthmus (90% of initial survivors); commonly along inferomedial aspect at level of left pulmonary artery
Aortic root (5-14% of initial survivors), Most die at scene of accident
Diaphragmatic hiatus (1-12%), May be associated with diaphragmatic injury
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5
Q
  1. Previous EVAR, sac increasing in size with evidence of contrast endoleak through porous graft materal

a) Type 1
b) Type 2
c) Type 3
d) Type 4
e) Type 5

A

d) Type 4

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6
Q
  1. Liver tumour between primary (primary is confluence of right and left hepatic duct, secondary is confluence of second order ducts) and secondary confluence - what type is it (Klatskin tumour question) – Bismuth Corlette classification.
Type 1
Type 2
Type 3a
Type 3b  
Type 4 Cholangio
A

*LW:
type I
limited to the common hepatic duct, below the level of the confluence of the right and left hepatic ducts

type II
involves the confluence of the right and left hepatic ducts

type IIIa
type II and extends to the bifurcation of the right hepatic duct

type IIIb
type II and extends to the bifurcation of the left hepatic duct

type IV
extending to the bifurcations of both right and left hepatic ducts
or
multifocal involvement

type V
stricture at the junction of common bile duct and cystic duct

Type 3a If right
Type 3b If left
Type 4 Cholangio If both

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7
Q
  1. Granulosa cell tumour question. Was either a 15 yo or a 30 yo woman with hyperestrogenism symptoms.

a) Granulosa cell tumour
b)
c)
d)
e)

A

a) Granulosa cell tumour

  • IVM additional information;
  • granulosa cell tumours can be seen in any age, but more commonly post menopausal (2/3)
  • Usually oetrogen secreting, but occasioanlly produce androen
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8
Q
  1. Infertility in a 25 yr old obese female with ultrasound demonstrating bilateral ovarian lesions with homogeneous low grade internal echogencity. Most likely

a) Endometrioma
b) PCOS
c) Teratoma
d) Mucinous cyst adenoma
e) Serous cyst adenoma

A

a) Endometrioma

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9
Q
  1. Infertility for 18 months - most likely cause
a)	polycystic ovaries
b)
c)
d)
e)
A

polycystic ovaries

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10
Q
  1. Criteria for PCOS - false?

a) Follicle size <10mm
b) Androgen exess
c) Anovulation
d) Follicles >12
e)

A

d) Follicles >12 used to be true, now >20

**LJS - Criteria for polycystic ovarian morphology:
>20 follicles per ovary and/or enlarged ovary >10ml
Other supportive findings (but not required for diagnosis):
Echogenic stroma - very vascular
Follicles at periphery of ovary - string of pearls
Follicles of similar size (2-9mm)

Need 2 from 3 of (and exclusion of other cause e.g. CAH):
Polycystic ovarian morphology on USS
Ovulatory dysfunction - oligo or anovulation
Clinical and biochemical signs of hyperandrogenism

Wji: as lotte says 2-9m follicles is a feature but not a diagnostic criteria. So when this question was written a. was false. D. is now also false.

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11
Q
  1. 3 year old boy with outward bowing of the knees and mild beaking of the medial metaphysis

a) physiologic
b) Blount disease
c) AVN
d) NF1
e)

A

b) Blount disease

Classic findings:
Tibial shaft in varus position.
Wedge shaped epiphysis- under developed, sloping medially with adjacent irregular physis
Medial metaphyseal beaking/spur.

NF1 gets tibial pseudoarthrosis

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12
Q
  1. Women with menorrhagia and dysmenorrhoea, ultrasound demonstrates heterogenous myometrium and smooth serosa.

a) Endometriosis
b) Uterine fibroids – Would have irregular serosa (most are subserosal)
c) Endometriosis – Adenomyosis??
d)
e)

A

Adenomyosis??

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13
Q
  1. Smoker 40 yr old woman with multiple cystic masses in and around the parotid on ultrasound on US

a) Warthins tumour
b) Pleomorphic adenoma
c) Metastasis
d) Sarcoidosis
e) Benign lympoepithelial lesions

A

Benign lympoepithelial lesions – Esp if history of HIV

a) Warthins tumour Older and male.
b) Pleomorphic adenoma - not usually multiple, but are hypoechoic and may b=have posterior aoustic enhancment
c) Metastasis - possible, mets to intraparotid nodes and cervical LN to explain surrounding masses
d) Sarcoidosis – Solid enlargement
e) Benign lympoepithelial lesions – Esp if history of HIV

  • ESG- favour mets if unilateral and includes truly extra-parotid lesions - BLELs and Sjogren shouldn’t be extra-parotid.
  • WJI - disagree. BLEL characteristically has associated cervical adenopathy and adenoid hypertrophy secondary to HIV
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14
Q
  1. 3 weeks old with torticollis, US shows sternomastoid (whatever that is?) MASS which is moderately vascular on US

a) Rhabdomyosarcoma
b) FIbromatosis colli
c) Capillary haemoangioma

A

b) FIbromatosis colli Presents with enalrgement of muscle (there can be a mass, no pain).

a) Rhabdomyosarcoma If mass and il-defined margins
b) FIbromatosis colli Presents with enalrgement of muscle (no mass, no pain).
c) Capillary haemoangioma Possible?

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15
Q
  1. Painful 2nd MTP and 2nd inter tarsal. Compressive sc hypo echoic fat layer 2 3 4 MT heads

a) interstitial bursitis
b) inter metatarsal bursitis

A

interstitial bursitis (adventitial bursitis)

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16
Q
  1. Tarlov cyst - what is correct

a) Most often affects the 1st and 4th sacral levels
b) often has bone erosion remodelling anyway
c) If multiple then it’s likely syndromic

A

b) often has bone erosion remodelling anyway

a) Most often affects the 1st and 4th sacral levels 2,3
b) often has bone erosion remodelling anyway
c) If multiple then it’s likely syndromic

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17
Q
  1. Bx of ilium - how do you do it. Depends on what you are doing it for

a) most direct route
b) ant approach
c) post approach
d) FNA
e) core

A

) core ?? um

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18
Q
  1. Breast - 40yo woman asymptomatic. Well defined hypo echoic lesion taller than wide, most likely.

a) IDC
b) ILC
c) mucinous

A

a) IDC – Most common
17. Breast - 40yo woman asymptomatic. Well defined hypo echoic lesion taller than wide, most likely

a) IDC – Most common
b) ILC Not well defined
c) mucinous Well defined but micro lobulated, often mixed solid cystic. Pure type can be anechoic (usually acoustic enhancement) - older patient (75 yo +)

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19
Q
  1. PASH

a) incidental no treatment
b) palpable mass
c) d)e)

A

a) incidental no treatment - True, usually microscopic incidental. No malignant potential (statdx).
b) palpable mass - True, sometimes.
Differential diagnosis for breast cancer- due to fibroblast proliferation- circumscribed/partially circumscribed mass, or architectural distortion- may look like fibroadenoma

Wide spectrum ranging from incidental finding to palpable mass
Most commonly incidental microscopic finding
Seen in 23% of breast biopsies and 19% of (healthy) mastectomies

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20
Q
  1. Fleischner guideline 3mm smoker

a) 12 month, then no followup
b) c)d)e)

A

a) 12 month, then no followupf/u because of high risk
Fleischner Society Recommendations and this table do NOT apply to:
Patients who have a known cancer.
Immunosuppressed patients.
Lung cancer screening, which has separate criteria.
Intra-fissural, perifissural, and subpleural pulmonary nodules. Perifissural lung nodules are usually benign, unless suspicious nodule morphology is present (reference).
Spiculated margins.
Displacement of the pulmonary fissure.
Cancer history.In these cases, follow-up should be considered.
Diameter of lung nodule is the average of the short and long axes, rounded to the whole millimeter.
Lung Cancer Risk Factors:
Tobacco use.
Family history of lung cancer.
Upper pulmonary lobe location of nodule.
Presence of emphysema.
Pulmonary fibrosis.
Older Age.
Female gender.

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21
Q
  1. ovarian cyst complex 3.5 cm young woman

a) 6 week followup different cycle If complex means multiseptated
b) 4 week followup same cycle
c) no followup if simple, or haemorrhagic
d) gynae blah

A

a) 6 week followup different cycle If complex means multiseptated

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22
Q
  1. Left ventricle atrial mass 80 yo screen for dementia. Cystic with minimal peripheral enhancement. What is most likely.

a) met
b) CP Ca
c) CP cyst
d) e)

A

c) CP cyst

a) met Not sure
b) CP Ca No. Essentially only in children
c) CP cyst
d) e)

Choroid plexus cyst, as in choroid plexus xanthogranuloma

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23
Q
  1. Posterior fossa mass excision hx, falx density, jaw cystic lesion skin lesion

a) Basal cell naevus
b) c) d)

A

a) Basal cell naevus

aka Gorlin or Gorlin-Goltz
Multiple keratocystic odontogenic tumors, basal cell carcinoma, medulloblastoma, intracranial dural calcifications, bifid ribs (Statdx).
Robbins includes ovarian fibroma, cleft lip/palate, vertebral segmentation, bifid, fused, missing or splayed ribs.

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24
Q
  1. 40 yo headache vomiting. Cyst +nodule but cyst not enhancing

a) HGBL
b) met
c) Astrocytoma
d) e)

A

a) HGBL

a) HGBL
b) met possible, (most common posterior fossa mass in adults)
c) Astrocytoma Younger
d) e)

Presume question means cyst not enhancing, but nodule is.
Cyst wall does not enhance in HGBL, but does 50% of the time in astrocytoma.

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25
Q
  1. Hx rheumatic fever. Now unwell with meningism. Heart murmur.

a) multiple ring enhancing lesion
b) leptomeningeal enhancement

A

a) multiple ring enhancing lesion - septic emboli

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26
Q
  1. Diffuse axonal injury which is most correct?

a. All are haemorrhagic
b. Affects cortex
c. Genu of corpus callosum usually affected
d. Dark on T2
e. Affects dorsal midbrain dorsolateral midbrain and upper pons

A

e. Affects dorsal midbrain dorsolateral midbrain and upper pons
26. Diffuse axonal injury which is most correct?

a. All are haemorrhagic 80% non-haemorrhagic (stat dx)
b. Affects cortex grey-white matter junction
c. Genu of corpus callosum usually affected 2/3rds splenium
d. Dark on T2 - if haemorrhage
e. Affects dorsal midbrain dorsolateral midbrain and upper pons

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27
Q
  1. Progressive SOB. Symmetric peribronchovasc nodules, small-mod effusions, nodes, multiple small nodules.

a) Sarcoidosis
b) HP effusions
c) lymphangitis carcinomatosis
d) UIP effusions
e) NSIP (was it one of the options?? not sure)

A

c) lymphangitis carcinomatosis
27. Progressive SOB. Symmetric peribronchovasc nodules, small-mod effusions, nodes, multiple small nodules.

a) Sarcoidosis - no effusion
b) HP effusions - no effusion - (CCF - can have effusion in cellular type Statdx).
c) lymphangitis carcinomatosis
d) UIP effusions - no effusion
e) NSIP (was it one of the options?? not sure) - no effusion

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28
Q
  1. Male progressive restrictive lung disease. Nonsmoker bibasal septal thickening sub pleural cysts bronchiectasis

a) UIP
b) NSIP
c) RB ILD
d) DIP
e)

A

a) UIP

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29
Q
  1. Parathyroid gland

a) best seen on T2
b) Doesn’t enhance well on MRI
c) Ectopic seen above superior aspect thyroid
d) e)

A

a) best seen on T2

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30
Q
  1. Periprosthetic hip replacement a year ago, sclerosis and lucency for 6 months?

a) Loosening without infection
b) Infection and loosing
c) infection without loosening

A

b) Infection and loosing Could be either or both.better to use In-111 WBC scan

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31
Q
  1. Myeloma detection

a) Better with X-ray screen than bone scan
b) c)d)e)

A

a) Better with X-ray screen than bone scan

Bone scans can be normal

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32
Q
  1. Papillary thyroid ca on bx. Next best thing

a) MRI with contrast
b) CT with contrast
c) I131
d) Tc99m scan
e)

A

b) CT with contrast

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33
Q
  1. Most correct regarding knee injury what is correct

a) mostly lipohaemarthrosis detectable with a fracture
b) segond can happen with osteoporosis
c) subtle sclerosis medial femoral condyle may represent fracture
d) e)

A

c) subtle sclerosis medial femoral condyle may represent fracture

lipohaemarthrosis - a/w intra-articular fracture

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34
Q
  1. 15 year old generalised bone pain. Enlarged ribs, vertebral height loss cardiomegaly.

a) Sickle cell
b) MPS
c) thalassaemia major
d) Glycogen storage
e) Fibrous dysplasia

A

again debate around sickle cell or thalassaemia majorthalassaemia has more expansion

*RY - would probably favour thalassaemia because of the expansion. Statdx describes the marrow replacement of sickle cell as very subtle, usually not detectable on plain radiograph. Rib expansion is well documented for thalassaemia, compression fractures also known to occur.

**SCS: Sickle cell and Thalassaemia get cardiomegaly from high cardiac output (LVH etc).

**wji -dahnert only talks about widened ribs in thalassaemia and h shaped vertebrae in sickle cell. This is unhelpful.

  1. 15 year old generalised bone pain. Enlarged ribs, vertebral height loss cardiomegaly.
    a) Sickle cell Probably most correct. Potentially but more infarcts, less expansion
    b) MPS
    c) thalassaemia major
    d) Glycogen storage – Adenomas of the liver
    e) Fibrous dysplasia – not generalised
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35
Q
  1. OCP use. Liver echo normal. No biliary tree dilatation. Jaundice

a) steatohepatitis - ? To have jaundice
b) cholestasis
c) fatty liver
d) e)

A

b) cholestasis ummm

**LJS ?? fatty liver or steatohepatitis should have echogenic liver at least, if not enlarged.

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36
Q
  1. CT liver vascular lesion. MRI with hepatobiliary agent (forgot its name) - hyperintense scar on delayed. Hyper early iso progressively on delayed

a) HCC
b) FNH
c) Adenoma
d) e)

A

b) FNH

  • *LJS - FNH scar is only supposed to enhance on typical Gad agents (not hepatobiliary agents). Everything else fits with FNH though
  • ESG disagree, hepatobiliary contrast agent will do everything that extracellular agents do (including enhancement of FNH central scar on 5 min delays), and in addition allow evaluation of hepatobiliary phase with FNH being iso- to hyper-intense (except for the central scar, which has now become hypointense).
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37
Q
  1. Breast cancer risk. Woman is 30. Mum at 60 and cousin at 60s. How would you advise screening?

a) 2 yearly screen starting at 45
b) Immediate MRI starting annually
c) Investigate then annual mammogram for life
d) annual ultrasound till 35 then annual mamm

A

a) 2 yearly screen starting at 45

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38
Q
  1. Breast implant - not sensitive on MRI

a) Rupture
b) free silicone
c) capsular contraction
d) Multifocal cancer
e) IDC

A

not sure

*RY - Probably capsular contraction (hardening, with rounding/deformation in later stages). Note the general disadvantage of breast MRI = low specificity for benign versus malignant abnormality. In terms of implants, MRI usually not needed for saline rupture because should be clinically apparent.

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39
Q
  1. Breast implant - if it ruptures we can tell which type it is on ultrasound…

a) intracapsular rupture
b) extracapsular rupture
c) d)e)

A

b) extracapsular rupture – snowstorm easier

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40
Q
  1. Which is better US vs MRI

a) intracapsular
b) extra capsular
c) capsule contour contraction

A

c) capsule contour contraction??

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41
Q
  1. Lesion femoral diaphysis cortex night pain

a) Osteoid osteoma
b) Ossifying fibroma

A

a) Osteoid osteoma

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42
Q
  1. Osteoblastoma

a) confined to vertebral body
b) smaller than 1.5cm at dx
c) Resolves
d) found in vertebra 1/3
e)

A

d) found in vertebra 1/3 (40% stat dx), mostly cervical

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43
Q
  1. Wrong option

a) Chance fracture almost always has neurologic involvement -
b) Tear drop fracture - ventral cord injury
c) DISH can fracture disc
d) remote vertebral injury in 2 different places 5%
e)

A

a) Chance fracture almost always has neurologic involvement -

  1. Wrong option
    a) Chance fracture almost always has neurologic involvement -
    b) Tear drop fracture - ventral cord injury true
    c) DISH can fracture disc true
    d) remote vertebral injury in 2 different places 5%
    e)
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44
Q
  1. About to do an intervention. on clopidogrel (antiplatelet) clexane (LMWH) and metformin

a) stop clopidogrel for 10 days and clexane 12 hours 5 days adequate for clopidogrel
b) Stop clopidogrel for 12 hours clean 10 days
c) Stop clopidogrel and Metformin
d) Stop Clean and Metformin
e)

A

a) stop clopidogrel for 10 days and clexane 12 hours 5 days adequate for clopidogrel

  1. About to do an intervention. on clopidogrel (antiplatelet) clexane (LMWH) and metformin only consider stopping metformin if renal inpairment
    a) stop clopidogrel for 10 days and clexane 12 hours 5 days adequate for clopidogrel
    b) Stop clopidogrel for 12 hours clean 10 days
    c) Stop clopidogrel and Metformin
    d) Stop Clean and Metformine)
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45
Q
  1. Lung bx - SOB. Post biopsy haemoptysis with focal area of haemorrhage in the right lower lobe posterior segment. Whats the best position.

a) Right side down
b) Left side down
c) supine
d) prone
e) sit up

A

a) Right side down Biopsy side down (although its posterior so could argue for supine)

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46
Q
  1. Indication for tube on PTX in 80yr old with traumatic pneumothorax

a) air fluid level
b) clear pleural line seen
c) lung collapsed to hila
d) ipsilateral mediastinal shift - contralateral implies tension
e)

A

c) lung collapsed to hila

Indicating >50%

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47
Q
  1. 30 yo woman. 4cm jejunum with loss of pattern followed by 5cm stricture, and fistula to the terminal ileum fistula.

a) Crohn
b) Coeliac
c) Scleroderma
d) SLE
e) Was it UC????

A

a) Crohn

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48
Q
  1. 30 yr old with slowly growing neck mass, deep to parotid extending to the parapharyngeal space

a) 1st branchial cleft
b) 2nd branchial cleft cyst
c) 3rd branchial cleft cyst
d) Infected node
e)

A
  • *LJS edit - caution calling branchial cleft cyst in adult - think cystic nodal met, esp p16 +ve SCC, even in young adult non-smokers. If branchial cleft cyst, location deep to parotid would make me think 1st branchial cleft. 3rd and 4th are infrahyoid neck, 2nd is typically below angle of mandible. From options listed, I would choose 1st branchial cleft cyst**
  • LW –> Work type II, 1st BCC can occur within parotid or PPS space, so legit.

Previous answer:
b) 2nd branchial cleft cyst can extend between carotid arteries and abut pharyngeal wall.

*LW
Brachial cleft common feature summary:

1st branchial cleaft cyst:
–> Cystic mass near pinna & EAC (Work type I) or extends from EAC to angle of mandible (Work type II)
Location
- Type I: Periauricular cyst or sinus tract: Anterior, inferior, or posterior to pinna & concha
- Type II: Periparotid cyst or sinus tract: More intimately associated with parotid gland, medial or lateral to CNVII
Superficial, parotid space, or parapharyngeal space (PPS).

2nd branchial cleft cyst:
–> Cystic neck mass posterolateral to submandibular gland, lateral to carotid space, anterior to SCM
Most are at or immediately caudal to angle of mandible
Location
- Type I: Deep to platysma muscle, anterior to SCM
- Type II: Anterior to SCM, posterior to submandibular gland, lateral to carotid sheath (Most common)
- Type III: Protrudes between ICA & ECA, may extend to lateral pharyngeal wall or superiorly to skull base
- Type IV: Adjacent to lateral pharyngeal wall, probably remnant of 2nd pharyngeal pouch
2nd branchial apparatus fistula extends from anterior to SCM, through carotid artery bifurcation, & terminates in tonsillar fossa

3rd branchial cleft cyst:
–> Unilocular, thin-walled cyst in upper posterior cervical space or lower anterior neck
Location
- Anywhere along course of 3rd branchial cleft or pouch
- Upper neck: Posterior cervical space
- Lower neck: Anterior border sternocleidomastoid muscle
- Rarely in submandibular space, lateral to cephalad hypopharynx
Classically, 3rd branchial fistula would exit base of pyriform sinus, course superior to superior laryngeal and hypoglossal nerves and inferior to glossopharyngeal nerve

4th Branchial cleft cyst:
–> Sinus tract extending from apex of pyriform sinus to lower anterior neck after barium swallow
Abscess in or adjacent to anterior left thyroid lobe
Location
- May occur anywhere from left pyriform sinus apex to thyroid lobe
- Commonly against or within superior aspect of left thyroid lobe or attached to thyroid cartilage
- Upper end may communicate with or be adherent to pyriform sinus

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49
Q
  1. Incidental pick up 2cm renal mass. On MRI T1 high T2 and post contrast enhancement

a) Clear cell
b) Papillary
c) Haemorrhagicadenomyolipoma
d) Proteinaceous cyst
e) Simple cyst

A

a) Clear cell probably
50. Incidental pick up 2cm renal mass. On MRI T1 high T2 and post contrast enhancement

a) Clear cell
b) Papillary shouldn’t be high T1
c) Haemorrhagic – if haemorrhagic adenomyolipoma
d) Proteinaceous cyst wouldn’t enhance
e) Simple cyst

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50
Q
  1. Jejunal intussusception. Most likely

a) Pancreatic divisum
b) dorsal agenesis
c) ectopic pancreas
d) annular
e) some other pancreas variant

A

c) ectopic pancreas

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51
Q
  1. Most common in small bowel in ileum causing intussusception

a) Small bowel carcinoid
b) Lymphoma
c) Adenocarcinoma
d) e)

A
  • *LJS edit - from radiographics paper: SB intussusception most commonly has benign lead point (less often neoplasm). Of neoplastic causes, mets are most common. Maybe the unrecalled answers were benign lesion or mets? Of those listed, I would choose adenocarcinoma, as it is most common. (I have assumed stem was about adults)**
  • WJI -disagree with Lotte. Agree with prior answer: lymphoma. Adenocarcinoma most common small bowel tumour overall (30-50%, carcinoid 25-30%, lymphoma 15-20%) BUT adenocarcinoma favours duodenum then jejunum over ileum. Carcinoid and lymphoma favour ileum. “Small bowel lymphoma” listed on RP in malignant causes of intussusception with colon adenocarcinoma and mets.

b) Lymphoma

  1. Most common in small bowel in ileum causing intussusception
    a) Small bowel carcinoid second most common malignancy of small bowel
    b) Lymphoma
    c) Adenocarcinoma most common malignancy of SB

https://pubs.rsna.org/doi/full/10.1148/rg.263055100

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52
Q
  1. 15 year old kid who med oncology referral US shows caecal wall thickening. Apps not seen

a) Typhilitis
b) Appendicitis
c) Colitis
d) Diverticultis
e)

A

a) Typhilitis

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53
Q
  1. Paraumbilical discharge, with mass in continuation with the bladder dome

a) Adenocarcinoma
b) SCC
c) TCC
d) e)

A

a) Adenocarcinoma

most common malignancy in urachal remnants

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54
Q
  1. Appendix inflammation on ultrasound. most correct

a) can be up to 6mm
b) surrounding fat less echogenic
c) fluid collection
d) vascular
e) caecal thickening

A

c) fluid collection

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55
Q
  1. Placenta within 1cm to os on 20 week anatomy scan, 4cm cx. Most likely

a) marginal
b) bladder overly filled
c) contraction
d) abruption
e) low lying placenta

A

*LW: Preferred option is bladder over filled.
I think over filled bladder is most likely, as why else would they state cervical length of 4cm, which is slightly increased from normal (3cm), as over filled bladder can increase cervical length, and a over distended bladdr can mimic a low lying placenta, as it stretches the lower uterine segment.
*RY - normal length at 20weeks is 4cm according to google, so low lying seems most correct. Boom. Mike drop. Get outta my house Logan.

  • *SCS: depends on if TV/TA. Re TA; MOH Obstetric USS guidelines say “TA assessment with a full bladder falsely elongates the cervical length”. In order to see anything TA, you need the bladder full - sonographic window.
  • also Obstetric guidelines; “Routine cervical length scanning at the time of the mid trimester ANATOMY scan is not currently recommended” they generally dont do TV scans at anatomy.
  • If TV scan -> LLP.
  • Im going with Disney prince… overfilled bladder on gameday.

Previous answer
e) low lying placenta

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56
Q
  1. PV bleed and pain. 3rd trimester. Retroplacental hypo echoic structure with septa

a) abruption
b) praevia
c) d)

A

a) abruption

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57
Q
  1. Cord insertion not at placenta most likely cause

a) velamentous cord
b) succenturiate
c) bilobed placenta
d) e)

A

velamentous cord insertion

  1. Cord insertion not at placenta most likely cause:

a) velamentous cord insertion marginal more common
b) succenturiate most commonly on main placenta, often marginal or velamentous
c) bilobed placenta
d) e)

58
Q
  1. Not associated with abnormal pulmonary vasculature

a) VSD
b) PDA
c) TOF
d) AP window
e) Coarctation

A

e) Coarctation
59. Not associated with abnormal pulmonary vasculature

a) VSD
b) PDA
c) TOF - reduced vascularity (RV outflow obstruction)

d) AP window ( seriously WTF)
* *SCS: note this is an actual condition… L>R shunt, AKA aortopulmonary septal defect. Clinicians (non radiologists) call it AP window…abnormal communication between the proximal aorta and the pulmonary trunk

e) Coarctation

LJS edit - infantile coarctation (preductal type) is ass/w PDA and hence RV hypertrophy and PA dilatation. Depends on whether age of patient given in stem

59
Q
  1. 10 week G1P0 abdo wall mass at junction of abdo wall and cord

a) normal gut herniation
b) gastroschisis
c) omphaloceole

A

a) normal gut herniation

**SCS physiological gut herniation should not persist after 12-13 weeks. starts 8 weeks
See the gut at base of umbilical cord.

60
Q
  1. Pregnant female, has a scan at 33 weeks (by LMP), had a scan at 7 weeks (dates baby at 35 wks), and then another scan at 20 weeks. Scan today shows baby measuring 32 weeks. Which is correct regarding which scan you should base the gestational age on and the current status of the fetus?

a. Date baby by 7 wk scan, baby small for gestational age
b. Date baby by LMP, baby normal for age
c. Date baby by 20 week scan
d. Date baby by LMP, ……

A

a. Date baby by 7 wk scan, baby small for gestational age

61
Q
  1. 3T vs 1.5T, which is incorrect?

a. Chemical shift artefact is increased at 3T
b. Magnetic shift artefact is increased at 3T.
c. The 300 gaus line is further from the bore of the magnet at 3T
d. On a T1 FSE image at 3T, CSF will be darker than grey matter

A

b. Magnetic shift artefact is increased at 3T. Never heard of this

  1. 3T vs 1.5T, which is incorrect?
    a. Chemical shift artefact is increased at 3T - true
    b. Magnetic shift artefact is increased at 3T. Never heard of this
    c. The 300 gaus line is further from/closer to (sorry can’t remember which one) to the bore of the magnet at 3T true if further from
    d. On a T1 FSE image at 3T, CSF will be darker than grey matter – true

GAUSS LINE: The gauss (symbol: G or Gs) is a legacy CGS unit of magnetic flux density, which was superseded by the tesla. One gauss is defined as one maxwell per cm2 (Mx/cm2), which equates to 10-4 tesla, and is therefore a small unit. This is one of the reasons for its stubborn persistence in some scientific fields and its common occurrence in the literature.One area in which it continues to be widely applied is in MRI safety, whereby a 5 gauss line is demarcated around the magnet in the scanning room to show the region of risk to close by electronic devices that may be affected by the field, e.g. cardiac pacemakers.

62
Q
  1. Which of these is correct?

a. Samarium-153 treats bone metastases by beta emission.
b. A 4 phase bone scan is flow, blood pool, 3 hr and 8hr
c. MDP absorption is greatest in bone and blood at 30 mins

A

a. Samarium-153 treats bone metastases by beta emission. And gamma

  1. Which of these is correct?
    a. Samarium-153 treats bone metastases by beta emission. And gamma
    b. A 4 phase bone scan is flow, blood pool, 3 hr and 8hr AND 24 hour
    c. MDP absorption is greatest in bone and blood at 30 mins (?)
63
Q
  1. Primary thoracic TB

a) upper lobe most common
b) Adult s can have lymph node involvement only
c) Paeds have more effusion than adult
d)
e) Kids often unilateral hilar and paratracheal nodes

A

*LW:
Favor option E as correct, per radiopedia.
Yes adults can have nodal involvement only, and seen 10-30% of time, so both correct, but I would favor E most correct

b) Adult s can have lymph node involvement only

  1. Primary thoracic TB
    a) upper lobe most common usually middle and lower lobes
    b) Adult s can have lymph node involvement only
    c) Paeds have more effusion than adult – Adults have more effusions.
    d)
    e) Kids often unilateral hilar and paratracheal nodes (usually on right), 90% of cases.
64
Q
  1. Female patient on the OCP, presents with headache. CT scan shows infarcts in the thalamus and basal ganglia infarcts. Which vein is thrombosed?

a. Inferior sagittal sinus
b. Superior sagittal sinus
c. Vein of Labbe
d. Cavernous sinus

A

a. Inferior sagittal sinus (internal cerebral vein better answer if an option).

65
Q
  1. Fibroadenolipoma – management?

a. Routine 2yrly screening
b. Mastectomy and axillary clearance
c. Follow up mammogram in 12 months
d. ?hookwire with surgical biopsy

A

a. Routine 2yrly screening

66
Q
  1. Radial scar management

a. Wide local excision with sentinel node biopsy
b. Hookwire with open biopsy
c. Mastectomy
d.

A

b. Hookwire with open biopsy

67
Q
  1. Hydroxy-apatite deposition disease, which is most correct?

a. Chronic progressive process
b. Supraspinatus and biceps tendon most commonly involved
c. Subscapularis more common than supraspinatusd.

A

Supraspinatus most common, then infrapsinatus..umm

68
Q
  1. Double bubble on AXR, contrast study demonstrates dilated proximal duodenum, thin trickle of contrast passing beyond the level of obstructing with a thin linear filling defect outlined by the contrast

a. Duodenal web
b. Duodenal atresia
c. Annular pancreas

A

a. Duodenal web

69
Q
  1. History of seizures, T2 hyperintensity in the medial temporal lobe, which is most likely?

a. DNET
b. Hippocampal sclerosis
c. Oligodendroglioma
d. Gemistocytic astrocytoma

A

a. DNET less common than mesial temporal sclerosis.
b. Hippocampal sclerosis might be this one

  1. History of seizures, T2 hyperintensity in the medial temporal lobe, which is most likely?
    a. DNET less common than mesial temporal sclerosis.
    b. Hippocampal sclerosis might be this one
    c. Oligodendroglioma 70% calcify, less common in temporal
    d. Gemistocytic astrocytoma
70
Q

Cystic lesion with an enhancing mural nodule in the brain, most likely?

a. Astrocytoma
b. Haemangioblastoma

A

a. Astrocytoma if young

b. Haemangioblastoma if adult and posterior fossa.

71
Q
  1. Idiopathic scoliosis, most correct?

a. Female 10-18yrs, convex to right
b. Female 10-18 yrs, convex to left
c. Male 10-18 yrs, convex to right
d. Male 10-18 yrs convex to left

A

a. Female 10-18yrs, convex to right

S shaped curve most common

  • *SCS: Radiopaedia.
  • Adolescent and juvenile idiopathic scoliosis is more common in girls and tends to have a right thoracic curve (dextroscoliosis).
  • Infantile idiopathic scoliosis is more common in boys and they tend to have a left thoracic scoliosis (levoscoliosis).
72
Q
  1. Gynae ultrasound, enlarged uterus with smooth contour, heterogeneous appearance, endometrial stripe 4mm, which is most likely?

a. Endometrial carcinoma
b. Adenomyosis
c. Leiomyomas

A

b. Adenomyosis

73
Q
  1. What is correct regarding contrast allergy

a) non iodinated contrast reaction kills less than 1/80000
b) seafood allergy contraindicated
c) premed 4 hours before if hydrocortisone.
d) premed good for major rather than minor allergy

A

a) non iodinated contrast reaction kills less than 1/80000

  1. What is correct regarding contrast allergy
    a) non iodinated contrast reaction kills less than 1/80000 wji-radiopaedia 1/170k
    b) seafood allergy contraindicated - incorrect
    c) premed 4 hours before if hydrocortisone. If prednisone have to give three doses 13, 7 and 1 hour before
    d) premed good for major rather than minor allergy - nope
74
Q
  1. Most likely testicular tumour to cause haemorrhagic mets

a. embryonal
B. choriocarcinoma
c. Leydig-sertoli cell
d. seminoma

A

B. choriocarcinoma

75
Q
  1. Most likely testicular tumour to follow an indolent cause
A. spermatocytic seminoma
B. lymphoma
C. leydig cell
D. sertoli cell
E. embryonal
A

A. spermatocytic seminoma

Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site. Pathologically, it is characterized by 3 distinct cell types, lack of cytoplasmic glycogen, and scant to absent lymphocytic infiltrate. Gain of chromosome 9 is the most consistent genetic abnormality. There have been few case reports of sarcomas arising in spermatocytic seminoma and only an occasional report of metastasis. It is important to differentiate this condition from its frequent mimics, such as classic seminoma and embryonal carcinoma, because patients with spermatocytic seminoma may not require further treatment after surgery.

*wji sertoli and leydig close 2nd, 90%benign

76
Q
  1. Which one is not an appropriate age range

A. seminoma 30-40
B. spermatocytic seminoma >60
C. yolk sac tumour 5-15
D. ?embyonal cell 20-40

A

C. yolk sac tumour 5-15 <3 year, Schiller Duval bodies, raised AFP

  1. Which one is not an appropriate age range
    A. seminoma 30-40
    B. spermatocytic seminoma >60
    C. yolk sac tumour 5-15 <3 year, Schiller Duval bodies, raised AFP
    D. ?embyonal cell 20-40

yolk sac tumour- aka endodermal sinus tumour - age < 2 - heterogenous solid mass with cystic component on ultrasound- schiller duval bodies- raised AFP- tx: orchitectomy

77
Q
  1. Which is true regarding dissection

A. 5-10% not associated with significant intimal tear
B. haemorrhage occurs between in the media
C. most occurring in young people are not associated with hypertension
D. it is rare to see cystic medial degeneration in those without dissection

A

WJI - possibly which is false as I think all except D are true. Single best answer I would chose B. as this is true and A. is actually an IMH (although this is correct in multiple prior recalls).

A. 5-10% not associated with significant intimal tear True (statDx), rupture of vasa vasorum

  1. Which is true regarding dissection
    A. 5-10% not associated with significant intimal tear True (statDx), rupture of vasa vasorum
    B. haemorrhage occurs between in the media (how it was actually written)
    C. most occurring in young people are not associated with hypertension True as well. Most in young people due to other abnormalities (eg valve disease, marfans, Ehlers Danlos, crack cocaine, pregnancy, collagen vascular disease, syphilis)
    D. it is rare to see cystic medial degeneration in those without dissection
    Cystic medial necrosis (CMN) is a disorder of large arteries, in particular the aorta- accumulation of basophilic ground substance in the media with cyst-like lesions.- occur in certain connective tissue diseases such as Marfan syndrome, Ehlers-Danlos syndrome, and annuloaortic ectasia
78
Q
  1. Most common location of carcinoid tumour
A. duodenum
B. proximal ileum
C. distal ileum
D. proximal jejunem
E. distal jejunem
A

C. distal ileum 45 percent midgut, 90% of these within 2 feet of ileocaecal valve

79
Q
  1. Stone in cystic duct causing intrahepatic dust dilatation

A. Mirrizzis syndrome-others

A

A. Mirrizzis syndrome

Mirizzi syndrome refers to an uncommon phenomenon which results in extrinsic compression of an extrahepatic biliary duct from one or more calculi within the cystic duct or gallbladder. It is a functional hepatic syndrome but can often present with biliary duct dilatation and can mimic other hepatobiliary pathologies such as cholangiocarcinoma 2.

80
Q
  1. Regarding mesothelioma

A. spares visceral pleura
B. is indistinguishable from adenocarcinoma macro and microscopically.-..can’t remember the rest

A

B. is indistinguishable from adenocarcinoma macro and microscopically.

  1. Regarding mesothelioma
    A. spares visceral pleura Involves later/less than parietal
    B. is indistinguishable from adenocarcinoma macro and microscopically.-..can’t remember the rest
81
Q
  1. Least associated with smoking
A. large cell
B. small cell
C. adeno
D. squamous
E. carcinoid
A

E. carcinoid And bronchoalveolar

Small cell strongest smoking association
Typical carcinoid the weakest association

82
Q
  1. Risk factor for both squamous and adenocarcinoma of the oesophagus

A. smoking
B. alcohol
C. hot beverages
D. h. pylori

A

A. smoking

B. alcohol (also true)

83
Q
  1. Squamous cell carcinoma of the oesophagus most correct

A. associated with strictures in the lower third
B. most commonly affects the middle third of the oesophagus
C. others….

A

B. most commonly affects the middle third of the oesophagus 50 percent stat Dx, 30% lower third. Adeno more common in the lower third (Barrett’s)

  1. Squamous cell carcinoma of the oesophagus most correct
    A. associated with strictures in the lower third
    B. most commonly affects the middle third of the oesophagus 50 percent stat Dx, 30% lower third. Adeno more common in the lower third (Barrett’s)
84
Q
  1. Wegeners granulomatosis. Repeat question –what’s not involved

A. Pulmonary arteries
B. Renal arteries
C. upper airways
D. lower airways

A

B. Renal arteries

The classic triad of organ involvement consists of:
lungs: involved in 95% of cases
upper respiratory tract / sinuses: 75-90%
kidneys: 80%

85
Q
  1. Best for flow cytometry

A. chloroma (myeloid sarcoma)
B. Ewings

A

A. chloroma (myeloid sarcoma)

86
Q
  1. If you had cystic lesion in the jaw, calcs in falx and skin lesions then what is it
A

A. Gorlin syndrome (AKA basal cell naevus syndrome)

87
Q
  1. B2 lesion of the breast

A. ADH
B. ALH
C. Collagenous something
D. DCIS? Not sure

A

C. Collagenous something - only benign lesion

88
Q
  1. With Paget’s disease of the breast

A. More than 50% of the time the nipple looks normal
B. Can have DCIS 50%
C. Can have invasive cancer 50%

A

C. Can have invasive cancer 50%

89
Q
  1. Most likely syndrome causing cancer in the right colon, caecum

A. Cowden
B. Peutz-Jeger
C. Lynch Syndrome

A

C. Lynch Syndrome

90
Q
  1. Breast ca lobulated appearance

A. medullary
B. Mucinous
C. Radial scar

A

mucinous

91
Q
  1. Regarding TB , most correct

A. Pleural effusion Child > Adult
B. Ghon focus is a peripheral area of caseous necrosis and an involved lymph node
C. can have single organ involvement in kidney / meninges and this does not imply active pulmonary involvement
D. Most likely happens in the upper lobe if primary

A

C. can have single organ involvement in kidney / meninges and this does not imply active pulmonary involvement

  1. Regarding TB , most correct
    A. Pleural effusion Child > Adult nope.
    B. Ghon focus is a peripheral area of caseous necrosis and an involved lymph node ghon complex
    C. can have single organ involvement in kidney / meninges and this does not imply active pulmonary involvement
    D. Most likely happens in the upper lobe if primary secondary
92
Q
  1. What is NOT sarcoid

A. non caseating granulomatous
B. basal meninigitis.
C. chronic glomerulonephritis
D. choroid retinitis - iritis

A

C. chronic glomerulonephritis

**LJS - agree, though sarcoid can also be ass/w proliferative GN

93
Q
  1. What is NOT Ankylosing Spondylitis

A. Aortitis
B. iritis
C. Shoulder/hip/etc
D. MTP involvement

A

D. MTP involvement

SD:
Associations
anterior uveitis (25-40%)
psoriasis
inflammatory bowel disease: ulcerative colitis/Crohn disease
osteopenia
cardiovascular disease
apical/upper lobe predominant interstitial lung disease with small cystic spaces (in ~1% of patients) 4
aortic valve disease / aortitis
secondary amyloidosis (rare)
cauda equina syndrome (rare)
94
Q
  1. CADASIL, least likely

A. NOTCH 3 gene,
B, arteriopathy distribution
C. large and haemorrhagic infarcts
D. anterior temporal and deep white matter

A

*LW: C - large haemorrgic infarcts - usually lacunar and micro bleeds

A. NOTCH 3 gene: TRUE

B, arteriopathy distribution: True, arteriopathy without atherosclerosis or amyloid, affecting basal ganglia, ant temporal lobe, deep white matter.

C. infarcts - large and haemorrhagic - FLASE: lacunar infarcts and microhaemorrhages:

D. anterior temporal and deep white matter: TRUE

B, arteriopathy distribution - leptomeningeal C. infarcts - large and haemorrhagic microhaemorrhages

95
Q
  1. Something about ADEM –what is NOT a feature?

A. Following bacterial infection
B. Is monophasic
C. Can involve cord and cerebral hemispheres

A

A. Following bacterial infection - rare

96
Q
  1. Conn syndrome - most characteristic

A. hyperkalaemia.
B. hyponatraemia
C. Adrenal cortical adenoma.

A

C. Adrenal cortical adenoma. Stat dx 80%, Radiopaedia 30%

  1. Conn syndrome - most characteristic:

A. hyperkalaemia. Increased aldosterone – reabsorption of Na and Excretion of K.
B. hyponatraemia
C. Adrenal cortical adenoma. Stat dx 80%, Radiopaedia 30% Conn’s- adrenal cortical adenoma 70%- Adrenal hyperplasia 30%- carcinoma

97
Q

28: Hashimoto disease, most correct

A. transient hyperthyroidism then hypothyroidism
B. small increased risk of ca – follicular lymphoma.
C…

A

A. transient hyperthyroidism then hypothyroidism

28: Hashimoto disease, most correct
A. transient hyperthyroidism then hypothyroidism
B. small increased risk of ca – follicular lymphoma. Marginal zone b-cell lymphoma, possible papillary thyroid carcinoma
C…

98
Q

29: Pituitary adenoma – what is NOT a feature

A. MEN 2
B. Micro more likely to be hormone secreting
C.

A

A. MEN 2

99
Q
  1. Least likely in twin pregnancy

A. Monozygotic with various combination?
B. fused DCDA INDICATES monozygotic
C. Risk of losing one of the two fetuses 1/8
D. DCDA means monozygotic

A

*LW:
DCDA doesn’t mean mono zygotic, monozygotic can occur in approx 20% of DCDA twins.

probably C. Risk of losing one of the two fetuses 1/8 more like 1/5
DCDA - more common in dizygotic- but can occur in monozygotic

Monozygotic twins can have any placentation type, depending on when zygote splits (single egg fertilised by single sperm)
Dizygotic always DCDA (two egoos fertilsed by two spermies)

WJI - b and d are both false. Fused appearing placenta and dcda can both be mono or dizygotic

100
Q
  1. BRCA 1 gene not likely

A. prostate ca
B. ovarian
C. pancreatic
D. choriocarcinoma

A

D. choriocarcinoma

SD:
BRCA1 mutation
breast cancer: ~65%
second primary breast cancer: ~30% at 5 years
male breast cancer: 1-2%
ovarian cancer: ~32.5%
prostate cancer: <30%
pancreatic cancer: ~2%
colorectal cancer: 5x increased risk if <50 years 4
101
Q
  1. Infection testes first but not epididymis
A. gonorrhoae 
B. TB 
C. Chlamydia 
D. E coli 
E. Syphilis
A

E. Syphilis - in robbins p974

Syphilis Saj: In a child - MUMPs can cause isolated orchitis
Crack the core -pg 114 vol 1

102
Q
  1. HSV

A. Haemorrhagic necrosis
B. HSV 1 more common in neonates
C. HSV 2 more is most common cause viral meningitis in adults

A

A. Haemorrhagic necrosis

103
Q
  1. 3 months post partum. Has gradually increasing headache and blurry vision? Most likely

A. Lymphocytic hypophysitis
B. Empty sella
C. Pituirary adenoma
E. Was it cranio?

A

A. Lymphocytic hypophysitis

Beware question that is immediate post-partum – Sheehan/apoplexy.
Lymphocytic hypophysitis is seen most frequently in women, with a F:M of ~ 9:1, and often in the postpartum period or the third trimester of pregnancy.

104
Q
  1. 3rd trimester bleeding, cord not attached to the placenta(was this RD?)

A. Succenturiate
B. Accessory
C. praevia

A

C. praevia

LJS - I think answer was something else, likely velamentous cord insertion - could look unattached?
Could also mean succinturiate lobe - no cord attached to the accessory lobe

105
Q
  1. Which is not a cause of moderate to massive splenomegaly?

a. Schistosomiasis
b. Sickle cell anaemia
c. Thalassemia major
d. Myelodysplasia
e. Burkitts lymphoma endemic and non-endemic

A

*LW: Favor Burkitts.

  • *LJS - agree
    https: //pubmed.ncbi.nlm.nih.gov/29460043/

a. Schistosomiasis: true (although cant find size breakdown)
b. Sickle cell anaemia: intially true
c. Thalassemia major: TRUE
d. Myelodysplasia: TRUE
e. Burkitts lymphoma endemic and non-endemic: I favor this to be the correct answer: per the following from UpToDate:
- -> Endemic (African) form presents as a jaw or facial bone tumor (picture 1) in 50 to 60 percent of cases. Primary involvement of the abdomen is less common. The primary tumor can spread to other extranodal sites, including mesentery, ovary, testis, kidney, breast, and meninges. Primary involvement of lymph nodes, mediastinum, and spleen are uncommon.
- -> non-endemic (sporadic) form usually has an abdominal presentation, most often with massive disease and ascites, involving the distal ileum, stomach (picture 2), cecum and/or mesentery, kidney, testis, ovary, breast, bone marrow, or central nervous system (CNS). Presenting symptoms can include those related to bowel obstruction or gastrointestinal bleeding, often mimicking acute appendicitis or intussusception. Approximately 25 percent of cases will have involvement of the jaw or facial bones. Lymphadenopathy, if present, is generally localized.

Previous answers:
b. Sickle cell anaemia may have Splenomegaly initially then infarcts.

e. Burkitts lymphoma endemic and non-endemic EJB thinks this one

  • Schistosomiasis causes splenomegaly with siderotic nodules and portal HTN
  • Burkitts listed as affecting solid abdominal organs in statdx but splenomegaly not specifically mentioned. Radiopedia mentions only kidneys/bowel
106
Q

signs of fetal demise on ultrasound

A

Ultrasound:

  • absent fetal heart beat
  • absent fetal movements
  • occasional findings:
    • overlapping of skull bones (Spalding sign)
    • gross distortion of fetal anatomy (maceration)
    • soft tissue oedema: skin >5 mm
    • echogenic amniotic fluid (fetal demise fragments)- uncommon findings
    • thrombus in fetal heart
    • gas shadow in fetal heart (Robert sign)​
107
Q
  1. Which is the least likely complication after acute myocardial infarction?

a. Acute mitral regurgitation
b. Acute aortic regurgitation
c. Fibrinous pericarditis
d. Pericardial tamponade
e. Left ventricular mural thrombus

A

b. Acute aortic regurgitation

108
Q
  1. Which is most correct?

a. Subacute bacterial endocarditis causes valvular destruction
b. Subacute bacterial endocarditis is complicated by emboli and aneurysms
c. Acute bacterial endocarditis….

A

*LW: maybe un recalled answer:
But A is technically correct, according to Robbins, but I would doubt it was the most correct option.

a. Subacute bacterial endocarditis causes valvular destruction: less valvular destruction than acute. Granulaiton tissue at bases. Pathoma states does not destroy valve.
b. Subacute bacterial endocarditis is complicated by emboli and aneurysms: known complication of acute bacterial endocarditis.

c. Acute bacterial endocarditis:
- friable bulky destructive vegetations
- Aortic and mitral most common
- Tricuspid in IVDU
-

probably b
a is right too

  1. Which is most correct?
    a. Subacute bacterial endocarditis causes valvular destruction but less so than acute
    b. Subacute bacterial endocarditis is complicated by emboli and aneurysms probably this one
    c. Acute bacterial endocarditis….
109
Q
  1. Which breast disease is most commonly associated with diabetes?

a. Fibroadenoma
b. PASH

A

Neither

SCS: Diabetic mastopathy?

110
Q

Which is most correct?

a. Pancreatic adenocarcinoma in the head of the pancreas is associated with normal parenchymal volume of the body and tail of the pancreas

A

usually atrophy

111
Q
  1. Which is not an indication for TIPS procedure?

a. Hepatorenal syndrome
b. Hepatopulmonary syndrome
c. Intractable ascites
d. Bleeding gastric varices
e. Fulminant liver failure

A

e. Fulminant liver failure

Good radiopaedia article. Along with right heart failure, sepsis, portal vein thrombosis.

**SCS: Hepatopulmonary syndrome is also a bit dubious. There are some papers reporting success but typical treatment is liver tx…. Fulminant liver failure is a (relative) contraindication.
HPS is not listed in the above radiopaedia article.

112
Q
  1. Which doesn’t involve the corpus callosum?

a. Lymphoma
b. Glioblastoma multiforme
c. Multiple sclerosis
d. Marchiafava-bignamie.
Can’t remember other option

A

– all the above do hahahahaha

113
Q
  1. Which is the most diagnostic feature of a GBM on histology?

a. Number of mitoses
b. Necrosis and vascular endothelial proliferation
c. Peripheral expansion beyond (?gross) tumour margins
d. Peri-lesional oedema extent

A

b. Necrosis and vascular endothelial proliferation

114
Q
  1. Which of the following does sarcoid not cause?

a. Glomerulonephritis

A

a. Glomerulonephritis

**SCS: sarcoid can cause interstitial nephritis.

115
Q
  1. Which of the following is not a feature of Wegeners?

a. Upper respiratory tract necrotizing granulomas
b. Lower respiratory tract necrotizing granulomas
c. Glomerulonephritis
d. Pulmonary arterial vasculitis
e. Renal arterial vasculitis

A

e. Renal arterial vasculitis

116
Q
  1. Hypocalcaemia is most likely in which of the following?

a. Parathyroid adenoma
b. Parathyroid carcinoma
c. Primary hyperparathyroidism
d. Secondary hyperparathyroidism
e. Tertiary hyperparathyroidism

A

d. Secondary hyperparathyroidism

Hypocalcaemia is the cause of increased PTH in this condition
-primary hyperparathyroidism
parathyroid adenoma (~80%)
multiple parathyroid adenomas (4%)
parathyroid hyperplasia (10-15%) 2,5
parathyroid carcinoma (1-5%)
-secondary hyperparathyroidism
caused by chronic hypocalcemia with renal osteodystrophy being the most common cause (others include malnutrition, vitamin D deficiency)
results in parathyroid hyperplasia
-tertiary hyperparathyroidism
autonomous parathyroid adenoma caused by the chronic overstimulation of hyperplastic glands in renal insufficiency

117
Q
  1. HPV causes which of the following?

a. Vocal cord polyps
b. Laryngoepiglottitis
c. Juvenile papillomatosis

A

**LJS - Vocal cord nodules/polyps - occur on true cords in singers/smokers due to chronic irritation, NOT HPV related. 9th Ed Rob p739

HPV lesions include:

  • Laryngeal papilloma/”squamous papilloma”. Benign neoplasm on true VC. Due to low risk HPV subtypes
  • Juvenile laryngeal papillomatosis - multiple papillomas, due to HPV (can be acquired at birth)

“Juvenile papillomatosis” is also the breast, not related to HPV

preferred option is C. juvenile papillomatosis.

118
Q
  1. Which feature is most likely to be seen in ulcerative colitis rather than Crohn’s disease?

a. Colonic pseudopolyps
b. Cholelithiasis

A

a. Colonic pseudopolyps

An inflammatory pseudopolyp is an island of normal colonic mucosa which only appears raised because it is surrounded by atrophic tissue (denuded ulcerative mucosa). It is seen in long-standing ulcerative colitis.

119
Q

Which is most correct regarding colonic fistulas to the urogenital tract?

a. Colo-vesical fistulae are more common in women
b. The most common cause is diverticulitis
c. Something about colo-vaginal fistula (?colovaginal fistula the connection can always be seen on CT)

A

b. The most common cause is diverticulitis

**SCS: Radiopaedia [colovesical fistula article]: Diverticulitis (60%). Colon cancer (~20%), Crohn Dis ( 10%). Other RTx, appendicitis, trauma.

120
Q
  1. CADASIL, which is least correct?

a. Infarcts are large and haemorrhagic
b. Something about predilection for frontal and temporal lobes?
c. Something about white matter involvement

A
  • LW:
    a. Infarcts are large and haemorrhagic: usually lacunar infarcts, with adjacent white matter changes. Can be haemorrhagic but less common.

*SCS:
CADASIL = cerebral autosomal dominant arteriopathy with Subcortical infarcts.
Distribution: anterior temporal pole, external capsule, paramedian frontal lobe (highly sens/spec). [StatDx].
NOTCH 3.

121
Q
  1. Which of the following causes and irregular uterine contour?

a. Leiomyomas
b. Adenomyosis
c. Endometrial
d. adenocarcinoma

A

a. Leiomyomas most common

Adenomyosis can also on HSG….

122
Q
  1. Risk factors for SCC and adenocarcinoma of oesophagus, which one do they have in common?

a. Tobacco
b. Alcoho
c. Hot drinks

A

a. Tobacco
b. Alcoho (and also this)

*LW:
UTD (which our exam is not) states the following regarding Adenocaricnoma of the oesphagus:
–> A meta-analysis of 20 case-control and four cohort studies including a total of 5500 cases concluded that there was no association between alcohol drinking and esophageal AC risk, even at higher levels of consumption.
So if correct recall, I would prefer smoking.

*AJL - Robbins says smoking and alcohol. If this was a correct recall, the most correct answer would be alcohol. Smoking can involve more than just tobacco technically….

123
Q
  1. BRCA-1 mutation is least likely to be associated with?

a. Pancreatic cancer
b. Male breast cancer although less common than BRCA 2
c. Prostate cancer
d. Endometrial cancer

A

d. Endometrial cancer

124
Q
  1. Regarding mesothelioma, which is most correct?

a. Can appear histologically (?and morphologically) identical to adenocarcinoma
b. Does not involve the visceral pleura
c. Association with smoking
d. Time lag is between 5-15 years
e. Despite being more common in asbestos exposure, Incidence still remains low in asbestos exposure (<0.01% ??)

A

a. Can appear histologically (?and morphologically) identical to adenocarcinoma

arises from either the visceral or the parietal pleura.
The lifetime risk of developing mesothelioma in heavily exposed individuals is as high as 7% to 10%.
There is a long latent period of 25 to 45 years for the development of asbestos-related mesothelioma, and there seems to be no increased risk of mesothelioma in asbestos workers who smoke. (SCS: note asbestos increases risk of primary lung cancer as well as mesothelioma. Is synergistic w smoking)

Microscopically, malignant mesotheliomas may be epithelioid (60%), sarcomatoid (20%), or mixed (20%). This is in keeping with the fact that mesothelial cells have the potential to develop as epithelium-like cells or mesenchymal stromal cells. The epithelioid type of mesothelioma consists of cuboidal, columnar, or flattened cells forming tubular or papillary structures resembling adenocarcinoma (Fig. 15-52A). Immuno­ histochemical stains are very helpful in differentiating it from pulmonary adenocarcinoma.

SCS: radiopaedia says hard to distinguish from METASTATIC adenocarcinoma.
‘The cytological and histological diagnosis can be difficult, with mesothelial hyperplasia and metastatic adenocarcinoma appearing similar’

125
Q
  1. Which cystic kidney disease is most commonly associated with RCC?

a. Acquired cystic renal disease
b. Autosomal recessive polycystic kidney
c. Autosomal dominant polycystic kidney

A

a. Acquired cystic renal disease
a. k.a. dialysis associated.

Patients with end-stage renal disease who have undergone prolonged dialysis sometimes show numerous cortical and medullary renal cysts. The cysts measure 0.1 to 4 cm in diameter, contain clear fluid, are lined by either hyper­ plastic or flattened tubular epithelium, and often contain calcium oxalate crystals. They probably form as a result of obstruction of tubules by interstitial fibrosis or by oxalate crystals. Most are asymptomatic, but sometimes the cysts bleed, causing hematuria. There is a 12- to 18-fold increased risk of renal cell carcinoma, which develops in 7% of dia- lyzed patients observed for 10 years.

126
Q
  1. Which syndrome commonly causes caecal/ascending colon carcinoma?

a. Gardners syndrome
b. Cowdens syndrome
c. Lynch syndrome
d. Peutz-Jeghers

A

c. Lynch syndrome

a. Gardners syndrome no predilection
b. Cowdens syndrome doesn’t increase risk of GI malignancy. LJS - get multiple hamartomas of skin, GIT
Breast cancer 30% ,lhermitte duclos ,5% follicular thyroid cancer ,multiple hamartomas including small and large bowel
c. Lynch syndrome 70% r sided
d. Peutz-Jeghers no predilection, hamartomas, often small bowel. **LJS - incr risk multiple malignancies including colonic adenocarcinoma, though polyps themselves not premalignant

127
Q
  1. Stomach and small bowel adenomas are associated with what?

a. Peutz-Jeghers
b. Familial adenomatous polyposis

A

b. Familial adenomatous polyposis

Pj are hamartomatous not adenomatous

128
Q
  1. Which is most correct?

a. 50% of Familial adenomatous polyp patients have carcinoma of the colon by age 30 and 100% by 50

A

yes

129
Q
  1. Which radiologically guided biopsy will be sent for flow cytometry?

a. Thymic carcinoma
b. Chloroma
c. ? neuroendocrine tumour

A

b. Chloroma (myeloid sarcoma)

130
Q
  1. Which one of these needs a core biopsy rather than an FNA?

a. Lymphoma in a lymph node
b. A secondary deposit in a lymph node
c. Thyroid carcinoma
d. Lung carcinoma

A

a. Lymphoma in a lymph node

131
Q
  1. ABC – most correct?

a. Is metaphyseal in > 50%
b. Is associated with giant cell tumour in ? %15

A

a. Is metaphyseal in > 50%

*AJL (addtional info)
ABCs are secondary in 1/3 of cases.
GCTs coexist with ABC 14% of the time (on GCT page of RP)

*wji agree a. Most correct 70-90% -but statdx says 1/3 abc secondary and 20-40% secondary is in gct so this is pretty much true also.

132
Q
  1. Pagets disease of the nipple

a. 50% have DCIS in the underlying breast
b. 50% have macroscopic changes in the nipple
c. 50% …… have idc

A

c. 50% …… have idc

133
Q
  1. Coeliac disease least accurate?

a. Proximal small bowel affected more than distal small bowel
b. Causes steatorrhoea
c. Causes villous atrophy with something or other

A

all true

134
Q
  1. Varices, which is least correct?

a. Linear filling defects parallel to the long axis of the oesophagus
b. Round sessile filling defect in the oesophagus
c. Can be caused by SVC obstruction
d. Can be caused by cirrhosis

A

b. Round sessile filling defect in the oesophagus

135
Q
  1. Which is most correct of prion diseases?

a. Present with rapidly progressive dementia and motor abnormalities
b. Prions contain mostly protein with a small amount of DNA and RNA
c. ? something about haemorrhage
d. In the early stage predominantly affects white matter
e. In the early stage predominantly affects basal ganglia and cortex
f. ? something about temporal lobes

A

a. Present with rapidly progressive dementia and motor abnormalities
e. In the early stage predominantly affects basal ganglia and cortex

CJD is thought to be mediated via prions, a type of protein, which manifests in sheep as the disease scrapie, and in cows as bovine spongiform encephalopathy. Prions are considered infectious in the sense that they can alter the structure of neighbouring proteins. CJD leads to spongiform degeneration of the brain, which is thought to be caused by the conversion of normal prion protein to proteinaceous infectious particles that accumulate in and around neurons and lead to cell death.

136
Q
  1. Carcinoid, which is least correct?

a. Neuroendocrine rests in a scar are unremarkable (??)
b. Atypical and typical carcinoid can’t be differentiated on histology
c. Carcinoid arises from metaplastic bronchial epithelial cells
d. All are malignant

A

*LW:
Both B and C are incorrect.
**LJS - agree

a. Neuroendocrine rests in a scar are unremarkable (??): TRUE
**LJS - agree
Tumourlets - small hyperplastic nests of neuroendocrine cells in scars/chronic inflammation - no clinical significance
Continuum of pulmonary NET: Benign tumourlets - typical carcinoid - atypical carcinoid - large cell neuroendocrine tumour - small cell carcinoma

b. Atypical and typical carcinoid can’t be differentiated on histology: FALSE, they can be.
* *LJS - Limited ability to differentiate on FNA but not on histology. Previous recalls have said FNA

c. Carcinoid arises from metaplastic bronchial epithelial cells: False arise from Kulchistsky cells / neuroendocrine cells that line bronchial mucosa.
d. All are malignant: I think true

137
Q
  1. Which structure is worst affected by Huntingtons disease?

a. Caudate nucleus
b. Hippocampus and ….

A

a. Caudate nucleus

138
Q
  1. Thyroid

a. In hyperthyroidism nuclear med scan should be the first investigation
b. In hyperthyroidism ultrasound should be the first investigation

A

a. In hyperthyroidism nuclear med scan should be the first investigation

139
Q
  1. Anti-smooth muscle antibodies are mostly likely positive in which condition?

a. ? psoriasis
b. ? Primary sclerosing cholangitis
c. ? primary biliary cirrhosis

A

*LW:
UpToDate: states anti smooth muscle antibodies are seen in PSC, (along with auto immune hepatitis) in up to 75% of patients, while pANCA seen in upto 80% of patients with PSC.
So….Based on options provided, I would chose PSC.

  • *LJS - agree LW
    https: //onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2036.2012.05223.x

Psoriasis - ?dunno
PSC - pANCA
PBC - AMA

Previous answer:
c. ? primary biliary cirrhosis

140
Q
  1. Which is the most correct finding to distinguish an exostosis from chondrosarcoma

a. Thickness of the cartilage cap
b. Pointing away from the joint
c. Medulla continuous with the medullary cavity of the origin bone

A

a. Thickness of the cartilage cap