Patel Flashcards
Strep A
Abrupt onset of sore throat Tonsillopharyngeal erythema and exudate Tender, enlarged anterior cervical LAD Winter and early spring peak incidence Dx: rapid test/ throat culture
Mono
Petechiae of palate Tonsillar enlargement Tender inguinal, axillary, or posterior auricular LAD Splenomegaly Adolescents and adults up to age 30
HSV
Gingivostomatitis and Pharyngitis together
Systemic illness with anorexia, & myalgia
Exudative, ulcerative lesions on pharynx.
Dx: culture from scrapping of the ulcer base.
EBV
Tender inguinal, axillary, or posterior, auricular LAD, Petechiae of palate, Tonsillar enlargement, Splenomegaly
Adolescents and adults up to age 30
Dx: Heterophile (“spot”)test, EBV anti-VCA IgM,IgG,IBNA test
HIV acute
symptoms, lasting up to 2 weeks
Painful mucocutaneous ulcerations on oral mucosa, penis, or anus
Nontender axillary, cervical, and
occipital LAD between 7 and 14 days
Nonpruritic, maculopapular
exanthem generalizing from face, chest to extremities—including palms and soles
Intravenous drug use, unprotected sexual intercourse, or other HIV exposure risks
Monospot
Positive for only acute infections
EBV and EA
Acute and reactivation positive
EBV and EBNA
Not positive in acute
EBV tx
Suportive care, prednisone for airway
No contact sports- 4 weeks
Regular sports- 3 weeks
M-trophic vs T-trophic HIV attachment
M- CCR5
T- CXCR4
Acute HIV
Long systemic flu like symptoms, rash, N/V
HIV testing
Eliza for gp120/140
Western for gp41/p24Ab for confirmation
HIV false negative
Early ART Partial seroconversion in acute HIV Advanced HIV with decline in p24 Ab. Infection with HIV-2 Immunosuppresion due to malignancy or medications.
HIV false positives
Alloantibody from pregnancy, other collagen vascular disease
Receipt of experimental HIV vaccine
4th gen elisa
p24 Ag used
