May Flashcards
Serum
Plasma minus clotting proteins
Hb + CO2
Carbaminohemoglobin
Hb + CO
Carboxyhemoglobin
Hypertonic solution
Crenation
RBC count
5million/ul
WBC count
4000-10000/ul
Hypotonic solution
Ghosting/lysis
Neutrophils granules
Hydrolases, myeloperoxidase, cathepsin g, collagenase, and elastase
Specific-Alk phos, lysozyme, collagenase
Also produce leukotrienes
Eosinophils granules
Specific- aryl sulfatase, histaminase, major basic protein and eosinophil cationic protein
Basophil granules
Specific- histamine, leukotrienes, SRS, heparin, eosinophil chemotactic factor, neutrophil chemotactic factor
Hemopoietic phases
Mesoblastic- 0-3 months
Hepatic- 1-10 months
Splenic- 2.5-6 months
Myeloid- 4 months on
CFU-S
GEMM Granulocytes Erythrocytes monocytes megakaryocytes
CFU-L
Lymphocytes
RBC development stages
Proerythroblast—Basophilic erythroblast—Polychromatophilic erythroblast—Orthochromatophilic erythroblast—-Reticulocyte—–RBC
Proerythroblast
1-2 nucleoli, basophilic, undergoes mitosis to make more
Basophilic erythroblast
More ribosomes with no nucleoli
Polychromatophilic erythroblast
Last stage of mitosis, obvious nuclear/cytoplasm nuclear changes
Granulocytopoiesis stages
Myeloblast—promyelocyte—myelocyte—-metamyelocyte—band—-mature
Myeloblast
Unable to tell between lineages, can undergo mitosis
Myelocyte
Where you can tell a difference between the lineages and is the last stage to undergo mitosis
Neutrophil kinetics
Medullary formation- Any that are developing
Medullary reserve- Ready to enter blood pool
Circulating pool
Marginal pool-Inner vessel walls
Metameylocyte
From here on, identify based on nuclear morphology
Primary nodule
Only present before birth
Secondary nodule
Germinal center present