Pasteurella Flashcards
Bacterial Resp Diseases IV
Structure ?
Gram-, rod or coccobacilli, facultative anaerobic, oxidase + (set them apart from other families)
“morse code” appearance of dots and dashes in Gram stain
some species produce toxins
have capsule and adhesins
Transmission ?
airborne direct transmission
environmental contamination and ingestion
infected bites, licks and scratches
Pathogenesis
3 manifestations of disease
1. resp tract (URT and pneumonia)
2. septicemia
3. trauma-associated
Diagnosis ?
CS and PM
lab tests on nasal swabs, tracheal washes or lung biopsy (culture, serology, serotyping, PCR, LAMP)
Immunity ?
after infection, there is a circulating antibody significant for protection
Control ?
regular testing
good environmental conditions
reservoir control
biosecurity
vaccines (variable efficacy)
Treatment
supportive (NSAIDs)
antibiotics (increasing rates of resistance)
Bovine Respiratory Disease (BRD), aka “shipping fever”. give
- pathogenesis
- detection method
- gross appearance
- histology
Pathogenesis involved stress factors interacting to suppress host defence mechanisms, leading to proliferation
farm staff evaluate stock health subjectively based on appearance and behaviour (limited sensitivity)
severe bronchopneumonia with areas of RBC lysis
no normal airway present, congestion and infiltrating neutrophils present, fibrin deposition of fibrin
Atrophic Rhinitis
- two types
- CS
- grading system
non-progressive (mild and transient, little effect)
progressive (toxigenic strain, severe and permanent)
- poor growth
- sneezing, coughing, inflammation of lacrimal duct
- nasal haemorrhage
- lateral deviation or shortening of the jaw
- turbinate atrophy
inflammation of the nares and atrophy (due to toxins) can be graded (0-4) in terms of increasing severity
Rabbit pasteruellosis key points
eye, ear and resp infection
see “snuffles” - mucopurulent rhinosinusitis
also see torticollis (“wry neck”)
Dog/Cat pasteruellosis key points
wide range of diseases
may cause a fatal pneumonia
Avian cholera key points
systemic infection
really nasty if in chronic form
Name the key species of pasteurella
P. multocida !!
also Mannheimia haemolytica, histophilus somni
