Pastest Orthopaedic For The MRCS Part A Flashcards
(248 cards)
Define seronegative Spondyloarthritis?
A group of disorders,characterised by
(1) Seronegative inflammatory arthritis or spondylitis
(2) primarily affect the spine and the sacroiliac joints.
True or False: Spondyloarthritis can lead to fusion of the spine.
True
Name one common symptom of Spondyloarthritis.
Chronic lower back pain and stiffness (sacroiliitis)
Fill in the blank: Spondyloarthritis is often associated with the _____ gene.
HLA-B27
What are the main types of Seronegative Spondyloarthritis?
Mnemonic;RAPE
(1) Ankylosing spondylitis,
(2) psoriatic arthritis,
(3) reactive arthritis, and
(4) enteropathic arthritis.
Multiple choice: Which of the following is NOT a characteristic of Spondyloarthritis?
A) Enthesitis
B) Dactylitis
C) Osteoporosis
D) Hyperuricemia
D) Hyperuricemia
What is the typical age of onset for Spondyloarthritis?
15-40 yrs in most Seronegative spondyloartheritis
True or False: Spondyloarthritis primarily affects women more than men.
False (males are 3-5 times more than females,i.e.,3-5 times more common in males)
What is enthesitis?
Inflammation of the entheses, the sites where tendons or ligaments insert into the bone.
Fill in the blank: Patients with Spondyloarthritis may experience _____, which is swelling of fingers or toes.
Dactylitis
What imaging technique is commonly used to assess Spondyloarthritis?
1st/ XRs
-Indications: (1) Sacroiliitis
(2) Inflammatory spinal pain
(≥ 3 months)
(3) Limited spinal movements
(4) Limited chest expansion
- Changes: in the following successive order
(1) Blurred joint margins
(2) Subchondral erosion
(3) Sclerosis or fusion of the sacroiliac joint
(4) Loss of lumbar lordosis ( Loss of lumbar lordosis with
restriction of movements in a young pt are highly
suggestive of ankylosing spondylitis)
(5) Bamboo spine ( the latest sign)
2nd/MRI
- Indications: Early stages of Ankylosing spondylitis (as changes may take many years to become evident on XRs)
Which medication class is commonly used for treating Spondyloarthritis?
Non-steroidal anti-inflammatory drugs (NSAIDs)
True or False: Spondyloarthritis can affect organs outside the musculoskeletal system.
True
What is the role of TNF-alpha inhibitors in Spondyloarthritis treatment?
1) reduce inflammation and
2) improve symptoms.
Multiple choice: Which condition is commonly associated with Spondyloarthritis?
A) Ulcerative colitis
B) Diabetes
C) Asthma
D) Hypertension
A) Ulcerative colitis
What is the primary genetic marker associated with Spondyloarthritis?
HLA-B27 antigen
Fill in the blank: Spondyloarthritis is characterized by _____ involvement and may lead to spinal stiffness.
Axial
What is reactive arthritis?
A form of Spondyloarthritis that occurs following an infection in another part of the body.
True or False: Spondyloarthritis can lead to cardiovascular complications.
True (aortic and non aortic valve disease,congestive heart failure,arrhythmias)
What lifestyle modification can help manage Spondyloarthritis symptoms?
1) Regular exercise and
2) physical therapy.
What is the significance of the Schober test in Spondyloarthritis?
It assesses lumbar spine mobility.
Multiple choice: Which of the following is a key feature of Ankylosing Spondylitis?
A) Asymmetric joint involvement
B) Bamboo spine
C) Rheumatoid nodules
D) Morning stiffness
B) Bamboo spine
What is the term for inflammation of the eye associated with Spondyloarthritis?
Anterior Uveitis
Fill in the blank: The presence of _____ is a diagnostic criterion for Ankylosing Spondylitis.
Sacroiliitis