Past q 19.12.16

Question 1

Which medicine is useful for decreasing tubular reabsorption?

Answer 1

Both
 Ascorbic acid
 Sodium bicarbonate

Question 2

Which statement is true?

Answer 2

After oral administration zinc can cause haemolysis, nephro- and hepato-toxicity

Question 3

Which statement is true for non-steroidal anti-inflammatory drugs?

Answer 3

Both
 Cats are highly susceptible to most of the NSAIDs
 During metabolism they are conjugated with glucoronate and glycine

Question 4

What kind of drugs can be used in the treatment of organochlorine poisoning

Answer 4

Diazepam

Question 5

What is characteristic to urea?

Answer 5

Both
 It’s application without prior adaptation can cause poisoning.
 Ammonia is produced from it by ruminal micro-organisms.

Question 6

Which mechanism of action is characteristic to snake venoms?

Answer 6

Beta-neurotoxins bind to the pre-synaptic membrane and inhibit nerve conduction.

Question 7

What are the clinical signs of acute Buckwheat poisoning?

Answer 7

Excitement, hyper-motility

Question 8

Which mechanism of action is characteristic to ochratoxin A?

Answer 8

It increases lipid peroxidation, and the level of reactive oxygen species.

Question 9

What is the recommended dose of atropine in organophosphate poisoning?

Answer 9

0.2 – 0.5 mg/kg BW

Question 10

Which substances show allergising effects?

Answer 10

Pesticides

Question 11

Which statement is true for anti-coagulant rodenticides?

Answer 11

Neither
Neither:
 Their toxicity is the same after single and multiple uptake nor
 They are well absorbed from the skin

Question 12

Which of the following mechanism of effect is characteristic to lead?

Answer 12

Binds to sulfhydryl groups of proteins.

Question 13

Which clinical signs are caused by Larkspur spp.?

Answer 13

Muscle weakness, bloat in ruminants, sudden death

Question 14

Which pathological alteration is characteristic to poisoning by cyanogenic glycosides?

Answer 14

Both
 The rumen is distended with gas
 Blood is bright cherry red and may not clot

Question 15

Which clinical feature is characteristic to chorine gas toxicosis?

Answer 15

Spasm of the glottis

Question 16

What is the recommended dose of sodium thiosulphate in cyanide poisoning?

Answer 16

500 – 1000 mg/kg BW

Question 17

Which pathological alteration is characteristic in urea poisoning?

Answer 17

Both
 Extreme bloating
 Ammonia odour of ruminal content

Question 18

What is not characteristic to phenocyacetic acid derivatives?

Answer 18

 Very toxic substances
Characteristic:
 They can increase the nitrate and cyanoglycoside content of plants
 Can become contaminated by dioxins during the manufacture
 They are herbicides with a stronger hormonal effect than auxins

Question 19

Which clinical signs are caused by poisonous lizards?

Answer 19

Both
 Tachycardia
 Severe pain

Question 20

Which statement is true?

Answer 20

Both
 The water solubility is advantageous for absorption of the compounds in the alveolar space
 Primarily the lipid soluble compounds can be absorbed from the skin

Question 21

Which medicine is useful in the treatment of poisoning by Larkspur spp.?

Answer 21

Physostigmine

Question 22

Due to their effect, the amount of ionized calcium is reduced in blood:

Answer 22

Alkalis

Question 23

What is the most toxic part of Golden chain?

Answer 23

Seed

Question 24

Which is a clinical feature of metaldehyde poisoning?

Answer 24

Both
 Ataxia, tremors
 Tachypnoe, dyspnoea

Question 25

Which compounds or classes of compounds lead to the production of enhanced levels of superoxide radicals in the lungs?

Answer 25

Paraquat

Question 26

Which is characteristic to poisoning by a cyanogenic glycoside?

Answer 26

The blood is bright cherry red

Question 27

Which clinical feature is characteristic to hydrogen sulphide toxicosis?

Answer 27

Neither Neither:  Causing flow (reddish colour) on the face nor  Vomiting

Question 28

Which of the following mechanism of effect is characteristic to arsenic?

Answer 28

Inhibits oxidative enzymes that are responsible for lipid and carbohydrate metabolism

Question 29

What is a clinical characteristic of acute ntirophenol poisoning?

Answer 29

Both  Salivation, vomiting, diarrhoea, abdominal pain  Increased frequency of breathing and heartbeat

Question 30

Which clinical sign is not characteristic to poisoning caused by household cleaners?

Answer 30

```  Respiratory distress Characteristic:  Dermatitis  Ulceration of stomach mucosa  Necrosis of oesophageal mucosa ```

Question 31

Which compound damages the cell membrane in a non-specific way

Answer 31

Paraquat

Question 32

What kind of treatment would you apply in hydrogen sulphide toxicosis?

Answer 32

Both  Fresh air  Antitussives

Question 33

Which mould fungi produce zearalenone?

Answer 33

Fusarium spp.

Question 34

What is the consequence if a xenobiotic accumulates in the tissues?

Answer 34

Chronic poisoning

Question 35

Which statement is true for salicylates?

Answer 35

Both  They are well absorbed from the stomach and small intestine.  They inhibit the aggregation of thrombocytes.

Question 36

Which is not a clinical feature of phosphine toxicosis?

Answer 36

```  Bloody diarrhoea Are clinical features:  Profuse vomiting  Pulmonary oedema  Strychnine-like convulsions ```