Past q 19.12.16 Flashcards
Which medicine is useful for decreasing tubular reabsorption?
Both
Ascorbic acid
Sodium bicarbonate
Which statement is true?
After oral administration zinc can cause haemolysis, nephro- and hepato-toxicity
Which statement is true for non-steroidal anti-inflammatory drugs?
Both
Cats are highly susceptible to most of the NSAIDs
During metabolism they are conjugated with glucoronate and glycine
What kind of drugs can be used in the treatment of organochlorine poisoning
Diazepam
What is characteristic to urea?
Both
It’s application without prior adaptation can cause poisoning.
Ammonia is produced from it by ruminal micro-organisms.
Which mechanism of action is characteristic to snake venoms?
Beta-neurotoxins bind to the pre-synaptic membrane and inhibit nerve conduction.
What are the clinical signs of acute Buckwheat poisoning?
Excitement, hyper-motility
Which mechanism of action is characteristic to ochratoxin A?
It increases lipid peroxidation, and the level of reactive oxygen species.
What is the recommended dose of atropine in organophosphate poisoning?
0.2 – 0.5 mg/kg BW
Which substances show allergising effects?
Pesticides
Which statement is true for anti-coagulant rodenticides?
Neither
Neither:
Their toxicity is the same after single and multiple uptake nor
They are well absorbed from the skin
Which of the following mechanism of effect is characteristic to lead?
Binds to sulfhydryl groups of proteins.
Which clinical signs are caused by Larkspur spp.?
Muscle weakness, bloat in ruminants, sudden death
Which pathological alteration is characteristic to poisoning by cyanogenic glycosides?
Both
The rumen is distended with gas
Blood is bright cherry red and may not clot
Which clinical feature is characteristic to chorine gas toxicosis?
Spasm of the glottis
What is the recommended dose of sodium thiosulphate in cyanide poisoning?
500 – 1000 mg/kg BW
Which pathological alteration is characteristic in urea poisoning?
Both
Extreme bloating
Ammonia odour of ruminal content
What is not characteristic to phenocyacetic acid derivatives?
Very toxic substances
Characteristic:
They can increase the nitrate and cyanoglycoside content of plants
Can become contaminated by dioxins during the manufacture
They are herbicides with a stronger hormonal effect than auxins
Which clinical signs are caused by poisonous lizards?
Both
Tachycardia
Severe pain
Which statement is true?
Both
The water solubility is advantageous for absorption of the compounds in the alveolar space
Primarily the lipid soluble compounds can be absorbed from the skin
Which medicine is useful in the treatment of poisoning by Larkspur spp.?
Physostigmine
Due to their effect, the amount of ionized calcium is reduced in blood:
Alkalis
What is the most toxic part of Golden chain?
Seed
Which is a clinical feature of metaldehyde poisoning?
Both
Ataxia, tremors
Tachypnoe, dyspnoea
Which compounds or classes of compounds lead to the production of enhanced levels of superoxide
radicals in the lungs?
Paraquat
Which is characteristic to poisoning by a cyanogenic glycoside?
The blood is bright cherry red
Which clinical feature is characteristic to hydrogen sulphide toxicosis?
Neither
Neither:
Causing flow (reddish colour) on the face nor
Vomiting
Which of the following mechanism of effect is characteristic to arsenic?
Inhibits oxidative enzymes that are responsible for lipid and carbohydrate metabolism
What is a clinical characteristic of acute ntirophenol poisoning?
Both
Salivation, vomiting, diarrhoea, abdominal pain
Increased frequency of breathing and heartbeat
Which clinical sign is not characteristic to poisoning caused by household cleaners?
Respiratory distress Characteristic: Dermatitis Ulceration of stomach mucosa Necrosis of oesophageal mucosa
Which compound damages the cell membrane in a non-specific way
Paraquat
What kind of treatment would you apply in hydrogen sulphide toxicosis?
Both
Fresh air
Antitussives
Which mould fungi produce zearalenone?
Fusarium spp.
What is the consequence if a xenobiotic accumulates in the tissues?
Chronic poisoning
Which statement is true for salicylates?
Both
They are well absorbed from the stomach and small intestine.
They inhibit the aggregation of thrombocytes.
Which is not a clinical feature of phosphine toxicosis?
Bloody diarrhoea Are clinical features: Profuse vomiting Pulmonary oedema Strychnine-like convulsions