past q 06.05.15 Flashcards
What is the effect of the venom of viperid snakes?
Both
Cardiotoxic
Neurotoxic
Which compound is found in bee venom?
Both
Histamine
Hyaluronidase
The bites of which ant species cause more severe species?
Solenopsis spp.
What is the most toxic part of Poinsetta?
Both
Sap
Leaf
What is not characteristic to the pharmacokinetic properties of organochlorines?
Quick elimination with the urine.
Characteristic:
Excellent absorption from the skin and mucous membranes.
Accumulation in the fat tissue.
Good distribution, penetration through the blood-brain barrier.
Which statement is true of the allergic effect?
The allergic effects are independent of dose.
In which type of cells can mutation develop?
Both
Somatic cells
Germ cells
What is the consequence if a xenobiotic accumulates in the tissues?
Chronic poisoning
Which clinical feature is characteristic to sulphur dioxide toxicosis?
Both
Bronchospasm
Coughing, hard breathing
Which clinical signs are caused by Bleeding heart?
Both
Opisthothonus
Hyperexcitability
Which antidote is not used in acute organophosphate toxicosis?
Fomepizole Used: Pralidoxim Atropine Obidoxim
Which is a clinical feature of NSAID toxicosis?
Both
Vomiting, faintness
Black faeces with melanoma
Which mechanism of effect is characteristic to metaldehyde?
Damaging the neurotransmitter in the nerve synapse.
Which statement is true of anatomical differences?
The skin of cat is more permeable than that of dog
Which statement is true to nitrate-nitrite?
Both
Methaemoglobin results from the presence of nitrite.
Monogastric animals are less sensitive to nitrates.
Which solution is useful for increasing of glomerular filtration?
Both
Mannitol solution
Glucose solution
Which antidote is useful in mercury poisoning?
Succimer
Which statement is true?
Neither
Neither:
Selenium has no physiological role in the body, it causes toxicosis also in very small amount nor
Anaphylactoid reaction can be caused by oral iron administration.
Which parameter is the ratio of LD50 and ED50?
Therapeutic index
Which mechanism of action is characteristic to diquat?
Fluid loss causes disturbance in the water homeostasis of the organism.
Which statement is true for methaldehyde?
The gastric acid facilitates its decomposition.
How would you treat xylitol toxicosis in animals?
Infusion containing glucose
What is the consequence if a xenobiotic accumulates in the tissues?
Chronic poisoning
Antidote in poisoning with diazinon and fenthion
Atropine
Which laboratory result is characteristic to haematuria form of Bracken fern poisoning?
Both
Prolonged clotting time
Increased levels of albumin and calcium in serum
Which antidote is not used in acute organophosphate toxicosis?
Fomepizole Used: Pralidoxim Atropine Obidoxim
Which is a clinical feature of NSAID toxicosis?
Both
Vomiting, faintness
Black faeces with melanoma
Which mechanism of effect is characteristic to metaldehyde?
Damaging the neurotransmitter in the nerve synapse.
Which substance or group of substances causes hypertrophy and hyperplasia of the thyroid gland?
Dithiocarbamates
Which statement is true of metabolic differences?
In swine, the glucuronic conjugation is more efficient than the sulphate reaction.
Which clinical signs are caused by Golden chain?
Both
Vomiting
Diarrhoea, incoordination
Which mechanism of action is characteristic to nitrate-nitrite?
It causes dilation of blood vessels via nitrogen monoxide liberation.
Which animal species is sensitive to ochratoxin?
Both
Poultry
Swine
Which is not a clinical feature of chronic copper toxicosis?
CNS signs Clinical features: Haemolytic crisis Icterus Haemoglobinuria