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Toxicology > past q 06.05.15 > Flashcards

past q 06.05.15 Flashcards

1
Q

What is the effect of the venom of viperid snakes?

A

Both
 Cardiotoxic
 Neurotoxic

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2
Q

Which compound is found in bee venom?

A

Both
 Histamine
 Hyaluronidase

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3
Q

The bites of which ant species cause more severe species?

A

Solenopsis spp.

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4
Q

What is the most toxic part of Poinsetta?

A

Both
 Sap
 Leaf

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5
Q

What is not characteristic to the pharmacokinetic properties of organochlorines?

A

Quick elimination with the urine.
Characteristic:
 Excellent absorption from the skin and mucous membranes.
 Accumulation in the fat tissue.
 Good distribution, penetration through the blood-brain barrier.

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6
Q

Which statement is true of the allergic effect?

A

The allergic effects are independent of dose.

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7
Q

In which type of cells can mutation develop?

A

Both
 Somatic cells
 Germ cells

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8
Q

What is the consequence if a xenobiotic accumulates in the tissues?

A

Chronic poisoning

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9
Q

Which clinical feature is characteristic to sulphur dioxide toxicosis?

A

Both
 Bronchospasm
 Coughing, hard breathing

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10
Q

Which clinical signs are caused by Bleeding heart?

A

Both
 Opisthothonus
 Hyperexcitability

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11
Q

Which antidote is not used in acute organophosphate toxicosis?

A 
Fomepizole
Used:
 Pralidoxim
 Atropine
 Obidoxim
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12
Q

Which is a clinical feature of NSAID toxicosis?

A

Both
 Vomiting, faintness
 Black faeces with melanoma

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13
Q

Which mechanism of effect is characteristic to metaldehyde?

A

Damaging the neurotransmitter in the nerve synapse.

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14
Q

Which statement is true of anatomical differences?

A

The skin of cat is more permeable than that of dog

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15
Q

Which statement is true to nitrate-nitrite?

A

Both
 Methaemoglobin results from the presence of nitrite.
 Monogastric animals are less sensitive to nitrates.

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16
Q

Which solution is useful for increasing of glomerular filtration?

A

Both
 Mannitol solution
 Glucose solution

17
Q

Which antidote is useful in mercury poisoning?

A

Succimer

18
Q

Which statement is true?

A

Neither
Neither:
 Selenium has no physiological role in the body, it causes toxicosis also in very small amount nor
 Anaphylactoid reaction can be caused by oral iron administration.

19
Q

Which parameter is the ratio of LD50 and ED50?

A

Therapeutic index

20
Q

Which mechanism of action is characteristic to diquat?

A

Fluid loss causes disturbance in the water homeostasis of the organism.

21
Q

Which statement is true for methaldehyde?

A

The gastric acid facilitates its decomposition.

22
Q

How would you treat xylitol toxicosis in animals?

A

Infusion containing glucose

23
Q

What is the consequence if a xenobiotic accumulates in the tissues?

A

Chronic poisoning

24
Q

Antidote in poisoning with diazinon and fenthion

A

Atropine

25
Q

Which laboratory result is characteristic to haematuria form of Bracken fern poisoning?

A

Both
 Prolonged clotting time
 Increased levels of albumin and calcium in serum

26
Q

Which antidote is not used in acute organophosphate toxicosis?

A 
Fomepizole
Used:
 Pralidoxim
 Atropine
 Obidoxim
27
Q

Which is a clinical feature of NSAID toxicosis?

A

Both
 Vomiting, faintness
 Black faeces with melanoma

28
Q

Which mechanism of effect is characteristic to metaldehyde?

A

Damaging the neurotransmitter in the nerve synapse.

29
Q

Which substance or group of substances causes hypertrophy and hyperplasia of the thyroid gland?

A

Dithiocarbamates

30
Q

Which statement is true of metabolic differences?

A

In swine, the glucuronic conjugation is more efficient than the sulphate reaction.

31
Q

Which clinical signs are caused by Golden chain?

A

Both
 Vomiting
 Diarrhoea, incoordination

32
Q

Which mechanism of action is characteristic to nitrate-nitrite?

A

It causes dilation of blood vessels via nitrogen monoxide liberation.

33
Q

Which animal species is sensitive to ochratoxin?

A

Both
 Poultry
 Swine

34
Q

Which is not a clinical feature of chronic copper toxicosis?

A 
 CNS signs
Clinical features:
 Haemolytic crisis
 Icterus
 Haemoglobinuria

Toxicology (8 decks)

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