Past papers Histopath Flashcards
cancer develops in Barrett’s oesophagus
adenocarcinoma
mechanism GORD -> cancer
metaplasia
body of stomach in pernicious anaemia
atrophy
Hy pylori cancer
MALT (or lymphoma)
Coeliac cancer
Enteropathy-associated Tc lymphoma
Caribbean and Japanese
HTLV-1
Adult Tc leukaemia/lymphoma
cancer, mycosis fungoides
Cutaneous Tc lymphoma
commonest breast malignancy
invasive ductal carcinoma
non-specific breast cancer
invasive ductal carcinoma
E-cadherin cancer
invasive ductal carcinoma
E-cadherin -ve= invasive lobular carcinoma
cancer with high, intermediate and low grade
DCIS
fibro-epithelial tumour with abundant stromal elements
pyllodes tumour
UTI, acute costovertebral pain
pus and blood in urine
acut pyelonephritis
loin-groin pain, haematuria
pain at end of micturition
calculus
frank painless haematuria
renal cell carcinoma
2y/o palpable abdo mass
Wilm’s tumour
PMH - AF
fever, N+V, right flank pain
renal infarct
heroin renal problem
focal glomerulonephritis
60 y/o abdo pain to back, collapses
AAA
ex-smoker, HTN and MI, sudden chest pain, radiates to back
descending internal carotid thrombus
AF plus flank pain
renal infarct
MI 3 years ago
sample from pericardial layer, blood aspirated
ventricular rupture
portal HTN clinical finding
splenomegaly
cancer asbestos
mesothelioma
transitional cell cancer
bladder
itchy skin features in
hepatitis
common ovarian tumour
serous cystadenoma (columnar epithelium)
ulcers on mouth after drug
Steven-Johnson syndrome
vector transmits Trypanosoma brucei rhodesiense
Tsetse Fly
Leishmaniasis (also known as Kala Azar) vector
Sandfly
True positives divided by the total number who have the disease
Sensitivity
Hepatitis that doesnt lead to chronic Hep
Hep A
cancer is most likely in a person who is a non-smoker
adenocarcinoma
mallory bodies
alcoholic hepatitis
child nephrotic syndrome cause
minimal change disease
cancer of 50 y/o midshaft femur fracture
chondrosarcoma
>40
(whereas Ewing/ osteosarcoma young adults)
diarrhoea, wt loss, biopsy granulomata
Crohn’s
middle age F, biopsy liver - loss bile ducts and granulomas
PBC
ALL blood count
neutropenia
indications for dialysis
AEIOU A - intractible acidosis E - electrolyte disturbance I - intoxiant e.g. methanol O - fluid overload U - uraemia Sx (N, seizure, pericarditis, bleed)
subtypes endometrial cancer
endometrioid (E2)- 80%
non-endometrioid (papillary,serous,clear cell)
breast bloody discharge, benign change
ductal papilloma
Cancer from Barret’s
Adenocarcinoma
Mechanism of GORD -> cancer
metaplasia
Body of stomach in pernicious anaemia
atrophic gastritis
H. pylori cancer
Gastric MALT
Coeliac disease cancer
Enteropathy-associated MALT
E-cadherin +ve
ductal
IDC
enzyme if low, leads to hyperuricemia/rise in blood uric acid
HPGRT
enzyme rate limiting step in haem biosynthesis pathway
ALA synthase
enzyme is raised in osteomalacia
Alkaline phosphatase
enzyme is raised in mumps
Amylase-S
amylase-P high in pancreatitis
raised biomarker in rhabdomyolysis
Creatinine kinase
HGPRT Deficiency resulting in urate overproduction
self mutilating, choreiform movements, mentally limited and gout
Lesch Nyhan
transitional cell cancer organ?
bladder
bone cancer
onion skin appearance
young adult
Ewing sarcoma
bone cancer
sunburst appearance X ray
young adult
osteosarcoma (commonest primary bone ca)