past paper q's

Question 1

basophilia is associated with?

Answer 1

CML

Question 2

what is it called when pregnant women has reduced platelets?

Answer 2

gestational thrombocytopenia

Question 3

what does myelodysplastic syndrome mean?

Answer 3

ineffective proliferation
differentiation

of abnormally maturing myeloid stem cells

Question 4

WBC - blood film findings
hypogranulated, hyposegmented neutrophils

Answer 4

myelodysplastic syndrome

Question 5

pseudo-pelger-huet anomaly?

Answer 5

myelodysplastic syndrome

Question 6

what is aplastic anaemia?

Answer 6

pancytopenia

hypocellular BM

Question 7

multiple myeloma kidney damage?

Answer 7

myeloma kidney - cast nephropathy most common

AL amyloid

Question 8

renal transplant patients have increased risk of which lymphoma?

Answer 8

ebv diffuse large b cell

Question 9

CLL tyrosine kinase inhibitor?

Answer 9

ibrutinib

Question 10

cll bcl2 inhibitor

Answer 10

venetoclax

Question 11

what is thrombin time?

Answer 11

Thrombin time is a measure of how long the blood’s plasma takes to form a clot

measures fibrinogen > fibrin

increased / prolonged in DIC

Question 12

sarcoidosis
granuloma is it caseating?

Answer 12

no
non caseating

also associated with hypercalcaemia

Hypercalcemia in sarcoidosis is due to the uncontrolled synthesis of 1,25-dihydroxyvitamin D3 by macrophages