PASSMEDICINE

Question 1

Is Rhd +ve a dominant or a recessive gene?

Answer 1

Dominant so at least one parent need to be Rh +ve for the child to have Rh +ve

Question 2

When would you give Anti-D and how many doses

Answer 2

• Not needed if both parents are Rh-ve
• Advised when mother is Rh-ve and father is RH +ve
• First dose is administered at 28 weeks
• Second dose should be administered within 72 hours of birth if baby is Rh+ve
• Also indicated post first trimester loss

Question 3

How do we determine the cause of a fever post-surgically

Answer 3

0-2 hours: most likely transfusion related
24hrs: Hospital acquired infection
Delayed/ 1 week: surgical site infection

Question 4

What happens if you have megaloblastic, microcytic anaemia but you start therapy for folate deficiency without checking whether it is due to folate/ B12 deficiency

Answer 4

Might have B12

Need IV B12 to prevent/ correct neurological damage

Question 5

At what temperature should RBCs be stored

Answer 5

4/6 degrees

Question 6

What does tranexamic acid block?

Answer 6

Plasmin

Question 7

Which MSK condition is commonly associated with thrombocytopenia?

Answer 7

RA

Question 8

What do the cells in Iron deficiency anaemia look like?

Answer 8

Pencil cells

Question 9

causes of a vitamin B12 deficient diet?

Answer 9

• pernicious anaemia: most common cause
• post gastrectomy
• vegan diet or a poor diet
• disorders of terminal ileum (site of absorption): Crohn’s, blind-loop etc
• metformin (rare)

Question 10

Blue lines In gingiva + normocytic anaemia=

Answer 10

Lead poisoning

Question 11

What cells is Hodgkins lymphoma commonly associated with?

Answer 11

Reed- stem berg cells

Question 12

Which type of cell is increased in a patient with a viral infection?

Answer 12

Lymphocytes

Question 13

A patient is transfused -ve group blood 0 and developed: swollen lips, tachycardia, loud sounding breathing and has previously had atopy. what do they have?

Answer 13

IgA deficiency