Passmed/Pastest/Capsule Flashcards
what are features of Still’s Disease
arthralgia
elevated serum ferritin
rash: salmon-pink, maculopapular
pyrexia
typically rises in the late afternoon/early evening in a daily pattern and accompanies a worsening of joint symptoms and rash
lymphadenopathy
rheumatoid factor (RF) and anti-nuclear antibody (ANA) negative
how do you manage Still’s Disease
NSAIDs - should be used first-line to manage fever, joint pain and serositis, they should be trialed for at least a week before steroids are added.
steroids may control symptoms but won’t improve prognosis
if symptoms persist, the use of methotrexate, IL-1 or anti-TNF therapy can be considered
what is Simmonds test
patient lies facing down with leg below knee hanging off the end of the bed with foot in dorsiflexion, calf is squeezed and if there is no plantarflexion movement of the foot then the achilles tendon is damaged - +ve = damage
what test should you do in a patient presenting with discitis
echocardiography - may have IE
what should you suspect in a patient with signs of sepsis and developing lower limb neuropathy, particularly if there is no pain
lumbar epidural abscess
whats leriche syndrome
Type of Peripheral Arterial Disease
Classically, it is described in male patients as a triad of symptoms:
- Claudication of the buttocks and thighs
- Atrophy of the musculature of the legs
- Impotence (due to paralysis of the L1 nerve)
what antibiotic is not recommended for prescription in patients taking methotrexate + why
trimethoprim due to it causing myelosuppression and fatal pancytopenia
what antibiotic is most associated with achilles tendon disorders
ciprofloxacin
what should be done before commencing someone on hydroxychloroquinine
opthalmology review due to retinopathy risk
what is Sheurmans disease
self-limiting skeletal disorder of childhood, where the vertebrae grow unevenly with respect to the sagittal plane; that is, the posterior angle is often greater than the anterior.
what is brown-sequard syndrome
rare neurological condition characterized by a lesion in the spinal cord which results in weakness or paralysis (hemiparaplegia) on one side of the body and a loss of sensation (hemianesthesia) on the opposite side.
what is mallet thumb
injury to the end of a finger that forces it to flex inwards
what test is used to diagnose menisceal tears + what is it
Thessaly’s test . The patient is supported by doctor and is asked to stand on the affected leg, flexed to 20 degree. The test is positive if there is pain on twisting knee
what FRAX score warrants a DEXA scan
10% or higher
what results are consistent with osteomalacia
low calcium, low phosphate, high ALP
what is lesch-Nyhan syndrome
inherited enzyme deficiency also known as ‘juvenile gout’. It is also linked with self injuring behaviour, cognitive impairment and nervous system impairment.
what is lesch-nyhan syndrome linked with
gout
In Gout, what are drug contraindiations for a Gout prescription
azathioprine, as this causes myelosuppression
in a scaphoid fracture what is the neurovascular structure that is most at risk
Dorsal carpal branch of the radial artery
what should be checked before starting azathioprine
thiopurine methyltransferase deficiency - causes myelosuppression
what is the imaging modality of choice when viewing the achilles tendon
ultrasound
what is a Hill-Sach lesion
a cortical depression in the posterolateral head of the humerus. It results from forceful impaction of the humeral head against the anteroinferior glenoid rim when the shoulder is dislocated anteriorly.