PASSMED Flashcards

1
Q

Main role if IL1

A

Induce fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What cytokine is responsible for hypotension

A

IL1-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

main immunoglobin in breast milk

A

Iga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

effects of il1

A
  • increase expression of adhesion on endothelium
  • release of NO
  • vasodilator
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what IG provides localised protection on mucous membranes

A

Iga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ACID- EGG-T

A

Type 1 Anaphylactic
Type 2 Cytotoxic
Type 3 Immune complex
Type 4 Delayed type

IgE
IgG
IgG
T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

First immunoglobulin secreted in response to infection

A

Igm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

IL-2 is mainly secreted by……..

A

Th1 cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which cell surface marker quantifies total T cell count?

A

CD3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What part of immunoglobulin is responsible for antigen affinity

A

Variable region

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Receptor for Epstein Barr virus

A

Cd21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What cell mediated organ rejection

A

B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Immunological changes seen in HIV

A

Reduction in CD4, IL2, NK function, hypersensitivity response
Increase in b cell activation, b2 microglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In the context of T cell development, what is the purpose of negative selection?

A

To eliminate T cells that react strongly with self-antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the primary target of the autoantibodies involved in the pathophysiology of myasthenia gravis?

A

Postsynaptic acetylcholine receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pernicious anaemia is an autoimmune condition caused by ….

A

Autoantibodies against gastric parietal cells and or / intrinsic factor

17
Q

Which of the following describes the function of T-helper 2 (Th2) cells?

A

Encourage B-cell antibody production

18
Q

Role of il3g

A

Stimulates differentiation and proliferation of b cells

19
Q

Role of IL5

A

Stimulate production of eosinophils

20
Q

what immunoglobulin activates b cells

21
Q

what ig leads to mast cell degranulation

22
Q

mechanism of anakinra

A

IL1 receptor antagonist

23
Q

helper t cells reocognise antigens presented by..

A

MHC CLASS 2

24
Q

what IL induce fever

A

1L1 and IL6

25
CHEMOTAXIS of neutrophils is what IL
il8
26
What do th2 producee
IL 4,5,6,10
27
macrophages produce what cytokine
IL1,6,
28
What does IL10 DO
inhibit th1 cytokine production
29
role of IL4
proliferation of b cells
30
what Ig provides immunity to helminths and worms
Ige