Pass the PSA Flashcards
TSH 0.3, what should you do to levothyroxine dose?
Decrease it
TSH 5.2, what should you do to levothyroxine dose?
Increase it
Cause of secondary hypothyroidism
Pituitary damage
Reduced TSH causing reduced TH
Secondary cause of hyperthyroidism
Pituitary tumour
1st line treatment of diabetic neuropathy
Duloxetine (SNRI)
Treatment of opioid overdose (low RR, drowsy)
Naloxone
Which pain killer can lower seizure threshold?
Tramadol
Which pain killer is good in renal failure because it isn’t really excreted?
Tramadol
Which drug do you give for first-line T2DM in BMI 18, creatinine 172?
Sulphonyurea e.g. gliclazide
First-line treatment of focal epilepsy
Lamotrigine
1st prescription for hyperkalaemia
10U actrapid with 100ml of 20% dextrose over 30 minutes
What interacts with warfarin to increase INR?
Erythromycin
Drugs to stop before surgery
I LACK OP Insulin Lithium Aspirin COCP K+ sparing diuretics Oral hypoglycaemics Perinopril (ACEi)
When should you ideally stop COCP before surgery?
4-6weeks!
What should you stop in haemoptysis and any bleeding?
Anticoagulants e.g. aspirin and enoxaparin
CYP450 inducers
PC BRAS Phenytoin Carbamazepine Barbiturates Rifampicin Alcohol (chronic excess) Sulphonyureas
CYP450 inhibitors
AODEVICE Allopurinol Omeprazole Dislfiram Erythromycin Valproate Isoniazid Ciprofloxacin Ethanol (acute)
When should you stop ACEi and K+ sparing diuretics before surgery?
The day of
Causes of hyperkalaemia
DREAD Diuretics (K+ sparing) and ACEi and dalteparin (LMWH) Renal failure Endocrine (Addison's) Artefact DKA!
Steroid side effects
Stomach ulcers Thin skin Edema Right heart failure Osteoporosis Infection Diabetes!!!!! Cushing's syndrome
NSAID contraindications
Clotting issues Heart failure Asthma Indigestion Renal failure
CHAIR
NSAID contraindications
Clotting issues Indigestion Renal failure Asthma! Heart failure
CHAIR
How much paracetamol in 30/500 tablet of co-codamol?
500mg
Typical maintenance fluid prescription in healthy individual
2 salty 1 sweet
1L bag of dextrose (8hr)
2L saline (8hr each)
Typical prophylactic LMWH for prophylaxis of blood clots in hospital
S/C 5000U dalteparin
Drug for nausea in heart failure
Metoclopramide
Drug for nausea in a normal patient
Cyclizine
Who shouldn’t get metoclopramide?
Parkinson’s patients
Drug causes of hypokalaemia
Loop diuretics
Thiazide diuretics
Side effects of ACEi
Cough
Worsen renal failure
Can trigger renal failure in renal artery stenosis
Hyperkalaemia
Rheumatoid pt on methotrexate, got a UTI and given trimethoprim, what should you do?
Stop the methotrexate (current infection)
Change trimethoprim because too much folate antagonism
Furosemide can lead to which electrolyte abnormalities?
Hyponatraemia
Hypokalaemia
Drugs to stop in hyperkalaemia
ACEi
Thiazide diuretics e.g. eplerone
Drug causes of neutropaenia
Clozapine
Carbimazole
Causes of microcytic anaemia
Iron deficiency
Thalassaemia
Sideroblastic