Pasmeds Flashcards
The expression of what substance is increased on endothelial cells after damage or oxidative stress
Vascular cell adhesion molecule 1
Binds to molecules on lymphocytes , monocytes and eosinophils to cause adhesion of these molecules to the endothelium
Does angina have infarction
No only ischaemia
What acute coronary syndrome has total occlusion
STEMI
SOCRATES
Site - central , left sister
Onset - sudden
Character - crushing
Radiation - left arm, neck and jaw
Associated symptoms - nausea, sweating , sob, clammy
Time- constant
Exacerbating / relieving - worsened by exercise better with gtn spray
Severity - often very severe
In what patients is no pain common for acs
Elderly
Diabetics
central crushing chest pain in a young patient with no cv risk factors or history
costochondritis
what medications carry a risk of heart block
beta blockers
When giving a combination of beta blockers and calcium channel blockers what is impoprtant
the latter is a dihydrpiridine
what is a contraindication to doing a ct coronary angiography
renal impairments
what conditions are needed for a patient with a stemi to have a pci
12hrs of symptom onset and 2 hours at hospital
ECG findings for STEMI
-ST-segment elevation > 1 mm in 2 contiguous limb leads OR > 2 mm in 2 contiguous chest leads; and
– NEW ONSET LEFT BUNDLE BRANCH BLOCK
-Hyperacute T-waves
Protective feature of aaa
Patients with dm
what would you see on ecg for aortic stenosis
Increased QRS complex voltage
Left axis deviation
Poor R-wave progression
Summary of mitral regurgitation
Pan systolic murmur radiates to apex
best heard 5th ic
S1 may be quiet
summary of aortic stenosis
- systolic ejection murmur radiates to carotid
- 2nd IC
- sOFT S2 SOUND
Summary of aortic regurgitation
- wide pulse pressure
- collapsing pulse
- early diastolic murmur
- IE mxc
most common cause of aortic regurgitation
infective endocarditis
what connective tissue disorder is aortic regurgitation commonly associated with
marfans
CHADVASC2 SCORE
C: 1 point for congestive cardiac failure.
H: 1 point for hypertension.
A2: 2 points if the patient is aged 75 or over.
D: 1 point if the patient has diabetes mellitus.
S2: 2 points if the patient has previously had a stroke or transient ischaemic attack (TIA).
V: 1 point if the patient has known vascular disease.
A: 1 point if the patient is aged 65-74.
Sc: 1 point if the patient is female
what is a common cause of afib
holiday heart syndrome - due to excess alcohol intake
Why would you choose DCCV over oral beta blockers in afib
- dccv if patient is haemodynamically unstable
patients with a high chadvasc2 score should be anti coagulated with ?
novel oral anti coagultant
no contraindication of beta blockers, haemodynically stable patient should be started with ……. for AF
BISOPROLOL
first line therapy for atrial flutter in haemodynamically stable px
AV node blocking agents
oral verapamil