Pasmeds Flashcards

1
Q

The expression of what substance is increased on endothelial cells after damage or oxidative stress

A

Vascular cell adhesion molecule 1
Binds to molecules on lymphocytes , monocytes and eosinophils to cause adhesion of these molecules to the endothelium

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2
Q

Does angina have infarction

A

No only ischaemia

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3
Q

What acute coronary syndrome has total occlusion

A

STEMI

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4
Q

SOCRATES

A

Site - central , left sister
Onset - sudden
Character - crushing
Radiation - left arm, neck and jaw
Associated symptoms - nausea, sweating , sob, clammy
Time- constant
Exacerbating / relieving - worsened by exercise better with gtn spray
Severity - often very severe

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5
Q

In what patients is no pain common for acs

A

Elderly
Diabetics

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6
Q

central crushing chest pain in a young patient with no cv risk factors or history

A

costochondritis

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7
Q

what medications carry a risk of heart block

A

beta blockers

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8
Q

When giving a combination of beta blockers and calcium channel blockers what is impoprtant

A

the latter is a dihydrpiridine

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9
Q

what is a contraindication to doing a ct coronary angiography

A

renal impairments

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10
Q

what conditions are needed for a patient with a stemi to have a pci

A

12hrs of symptom onset and 2 hours at hospital

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11
Q

ECG findings for STEMI

A

-ST-segment elevation > 1 mm in 2 contiguous limb leads OR > 2 mm in 2 contiguous chest leads; and
– NEW ONSET LEFT BUNDLE BRANCH BLOCK
-Hyperacute T-waves

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12
Q

Protective feature of aaa

A

Patients with dm

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13
Q

what would you see on ecg for aortic stenosis

A

Increased QRS complex voltage
Left axis deviation
Poor R-wave progression

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14
Q

Summary of mitral regurgitation

A

Pan systolic murmur radiates to apex
best heard 5th ic
S1 may be quiet

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15
Q

summary of aortic stenosis

A
  • systolic ejection murmur radiates to carotid
  • 2nd IC
  • sOFT S2 SOUND
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16
Q

Summary of aortic regurgitation

A
  • wide pulse pressure
  • collapsing pulse
  • early diastolic murmur
  • IE mxc
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17
Q

most common cause of aortic regurgitation

A

infective endocarditis

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18
Q

what connective tissue disorder is aortic regurgitation commonly associated with

A

marfans

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19
Q

CHADVASC2 SCORE

A

C: 1 point for congestive cardiac failure.
H: 1 point for hypertension.
A2: 2 points if the patient is aged 75 or over.
D: 1 point if the patient has diabetes mellitus.
S2: 2 points if the patient has previously had a stroke or transient ischaemic attack (TIA).
V: 1 point if the patient has known vascular disease.
A: 1 point if the patient is aged 65-74.
Sc: 1 point if the patient is female

20
Q

what is a common cause of afib

A

holiday heart syndrome - due to excess alcohol intake

21
Q

Why would you choose DCCV over oral beta blockers in afib

A
  • dccv if patient is haemodynamically unstable
22
Q

patients with a high chadvasc2 score should be anti coagulated with ?

A

novel oral anti coagultant

23
Q

no contraindication of beta blockers, haemodynically stable patient should be started with ……. for AF

A

BISOPROLOL

24
Q

first line therapy for atrial flutter in haemodynamically stable px

A

AV node blocking agents
oral verapamil

25
Q

slurred upstroke of qrs complex suggests

A

Wolff parkinson white syndrome

26
Q

common presentation of wolff parkinson white syndrome

A

Young patient with flutters and palpitations
ECH shows sloped qrs complex

27
Q

what medications can cause long qt syndrome

A

Amiodarone,
Tricyclic Antidepressents
Antibiotics,
Fluconazole,
Erythromycin,
Metoclopramide,
Quinidine,
Haloperidol,
Ondansetron,
SSRIs

28
Q

What alzheimer drug can lead to third degree heart block

A

Donepzil

29
Q

Main difference between mobitz 1 and 2

A

Type 1 prolongation of pr until it drops
Type 2 constant pr and p waves that are not often followed by qrs

30
Q

Inheritance pattern for HOCM

A

Autosomal dominant

31
Q

Typical presentation of HOCM

A

Young patient with syncope and chest palpitations , a parent died at a young age

32
Q

What causes the ductus arteriosus to close

A

Decreased levels of prostaglandins

33
Q

Egg on side CXR would indicate

A

Transposition of the great arteries

34
Q

most common organism to cause infective endocarditis

A

s aureus

35
Q

most common complication of IE and how it would show on ecg

A

S aureus
prolonged pr interva;

36
Q

St segment elevation in what leads what show lad occlusion

A

V1-V4

37
Q

Common complication of pericarditis

A

Pericardial effusion

38
Q

Chest pain relieved by sitting up and worse when lying down

A

Pericarditis

39
Q

Name 4 defects in tetraology of fallot

A
  • overriding aorta
  • pulmonary stenosis
  • right ventricular hypertrophy
  • ventricular septal defect
40
Q

causes of secondary hypertension

A
  • phaeochromocytoma
  • hyperaldosteronism
  • stress
  • renal artery stenosis
  • preeclampsia
41
Q

what is kussmaul’s sign

A

jugular venous pulse rises with inspiration.

42
Q

patients with turners syndrome have htn due to ….?

A

Coarctation of the aorta distal to the left subclavian artery

43
Q

fine bibasal crackles and a displaced apex beat are indicative of ?

A

Pulmonary oedema in HF

44
Q

wells score

A

risk of dvt

45
Q

ANN ARBOR staging ?

A

lymphoma staging

46
Q

dukes criteria

A

IE likelihood