Pasmeds Flashcards

1
Q

The expression of what substance is increased on endothelial cells after damage or oxidative stress

A

Vascular cell adhesion molecule 1
Binds to molecules on lymphocytes , monocytes and eosinophils to cause adhesion of these molecules to the endothelium

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2
Q

Does angina have infarction

A

No only ischaemia

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3
Q

What acute coronary syndrome has total occlusion

A

STEMI

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4
Q

SOCRATES

A

Site - central , left sister
Onset - sudden
Character - crushing
Radiation - left arm, neck and jaw
Associated symptoms - nausea, sweating , sob, clammy
Time- constant
Exacerbating / relieving - worsened by exercise better with gtn spray
Severity - often very severe

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5
Q

In what patients is no pain common for acs

A

Elderly
Diabetics

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6
Q

central crushing chest pain in a young patient with no cv risk factors or history

A

costochondritis

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7
Q

what medications carry a risk of heart block

A

beta blockers

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8
Q

When giving a combination of beta blockers and calcium channel blockers what is impoprtant

A

the latter is a dihydrpiridine

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9
Q

what is a contraindication to doing a ct coronary angiography

A

renal impairments

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10
Q

what conditions are needed for a patient with a stemi to have a pci

A

12hrs of symptom onset and 2 hours at hospital

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11
Q

ECG findings for STEMI

A

-ST-segment elevation > 1 mm in 2 contiguous limb leads OR > 2 mm in 2 contiguous chest leads; and
– NEW ONSET LEFT BUNDLE BRANCH BLOCK
-Hyperacute T-waves

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12
Q

Protective feature of aaa

A

Patients with dm

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13
Q

what would you see on ecg for aortic stenosis

A

Increased QRS complex voltage
Left axis deviation
Poor R-wave progression

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14
Q

Summary of mitral regurgitation

A

Pan systolic murmur radiates to apex
best heard 5th ic
S1 may be quiet

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15
Q

summary of aortic stenosis

A
  • systolic ejection murmur radiates to carotid
  • 2nd IC
  • sOFT S2 SOUND
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16
Q

Summary of aortic regurgitation

A
  • wide pulse pressure
  • collapsing pulse
  • early diastolic murmur
  • IE mxc
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17
Q

most common cause of aortic regurgitation

A

infective endocarditis

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18
Q

what connective tissue disorder is aortic regurgitation commonly associated with

A

marfans

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19
Q

CHADVASC2 SCORE

A

C: 1 point for congestive cardiac failure.
H: 1 point for hypertension.
A2: 2 points if the patient is aged 75 or over.
D: 1 point if the patient has diabetes mellitus.
S2: 2 points if the patient has previously had a stroke or transient ischaemic attack (TIA).
V: 1 point if the patient has known vascular disease.
A: 1 point if the patient is aged 65-74.
Sc: 1 point if the patient is female

20
Q

what is a common cause of afib

A

holiday heart syndrome - due to excess alcohol intake

21
Q

Why would you choose DCCV over oral beta blockers in afib

A
  • dccv if patient is haemodynamically unstable
22
Q

patients with a high chadvasc2 score should be anti coagulated with ?

A

novel oral anti coagultant

23
Q

no contraindication of beta blockers, haemodynically stable patient should be started with ……. for AF

A

BISOPROLOL

24
Q

first line therapy for atrial flutter in haemodynamically stable px

A

AV node blocking agents
oral verapamil

25
slurred upstroke of qrs complex suggests
Wolff parkinson white syndrome
26
common presentation of wolff parkinson white syndrome
Young patient with flutters and palpitations ECH shows sloped qrs complex
27
what medications can cause long qt syndrome
Amiodarone, Tricyclic Antidepressents Antibiotics, Fluconazole, Erythromycin, Metoclopramide, Quinidine, Haloperidol, Ondansetron, SSRIs
28
What alzheimer drug can lead to third degree heart block
Donepzil
29
Main difference between mobitz 1 and 2
Type 1 prolongation of pr until it drops Type 2 constant pr and p waves that are not often followed by qrs
30
Inheritance pattern for HOCM
Autosomal dominant
31
Typical presentation of HOCM
Young patient with syncope and chest palpitations , a parent died at a young age
32
What causes the ductus arteriosus to close
Decreased levels of prostaglandins
33
Egg on side CXR would indicate
Transposition of the great arteries
34
most common organism to cause infective endocarditis
s aureus
35
most common complication of IE and how it would show on ecg
S aureus prolonged pr interva;
36
St segment elevation in what leads what show lad occlusion
V1-V4
37
Common complication of pericarditis
Pericardial effusion
38
Chest pain relieved by sitting up and worse when lying down
Pericarditis
39
Name 4 defects in tetraology of fallot
- overriding aorta - pulmonary stenosis - right ventricular hypertrophy - ventricular septal defect
40
causes of secondary hypertension
- phaeochromocytoma - hyperaldosteronism - stress - renal artery stenosis - preeclampsia
41
what is kussmaul's sign
jugular venous pulse rises with inspiration.
42
patients with turners syndrome have htn due to ....?
Coarctation of the aorta distal to the left subclavian artery
43
fine bibasal crackles and a displaced apex beat are indicative of ?
Pulmonary oedema in HF
44
wells score
risk of dvt
45
ANN ARBOR staging ?
lymphoma staging
46
dukes criteria
IE likelihood