PARVO Flashcards
1
Q
Surface feature of capsid
*5-fold
*3-fold
*2-fold
A
- 5-fold - hollow cylinder
- 3-fold - protrusion
- 2-fold - depressions
2
Q
Give two proteins of ORF 1 and where are they located?
A
3’ end of genome
NS1 & NS2
3
Q
Give two proteins of ORF 2 and where are they located?
A
5’ end of genome
VP1 & VP2
4
Q
(1) function of NS1
A
binds to DNA and required for viral DNA replication
5
Q
function of NS2
A
formed by splicing, regulates viral gene expression
6
Q
NS1 mediates arrest of cell in the ____ phase of cell cycle
A
G1 phase
7
Q
(2) receptor binding of parvo
A
- Transferrin - CPV, FPV
- Sialic acid - rodent parvo
8
Q
intermediates in parvo
A
ds DNA intermediates
9
Q
FPV targets ____ in kittens infected in perinatal stage
A
cerebellum (hypoplasia)
10
Q
lesions in Duck Parvovirus (2)
A
- stunting
- feathering is delayed
11
Q
lesions in Goose Parvovirus
A
necrotizing hepatitis
12
Q
Continuously dividing cells in older animals (3)
A
- Hematopoietic precursors
- Lymphocytes
- Progenitor cells in intestinal mucosa
