Partial Fatty Acid Oxidation Inhibitor

Question 1

Drug which dec fatty acid oxidation in heart

Answer 1

Trimetazidine

Question 2

Purpose of trimetazidine usage

Answer 2

Glucose more efficient source of v energy and Lester production of free radicals

Question 3

RANOLAZINE MOA

Answer 3

BLOCKS NA ENTRY WHICH FACILITATED CA ENTRY THROUGH NCX CHANNEL
HENCE CA DOESNT GET TO ENTER

Question 4

Ex of first line chronic angina drug

Answer 4

Ranolazine

Question 5

RANOLAZINE hr and BP

Answer 5

No effect on both

Question 6

RANOLAZINE and sildenafil

Answer 6

Can be used togather

Question 7

NCX channel inhibitors causing qt prolongation

Answer 7

RANOLAZINE

Question 8

RANOLAZINE and anti arrythmics

Answer 8

Contraindicated when class 1 and 3 are used

Question 9

RANOLAZINE and

CYP 450 3a inhibitors

Answer 9

Contraindicated

Question 10

RANOLAZINE and AFIB

Answer 10

dec occurance

Question 11

RANOLAZINE in significant liver and kidney disease

Answer 11

Contraindicated

Question 12

RANOLAZINE and acute angina

Answer 12

Contraindicated

Question 13

Funny current blocker

Answer 13

Ivabradin

Question 14

Ivabradin is tachycardia or bradycardia inducing

Answer 14

Bradycardiac agent

Question 15

Side effect of Ivabradin

Answer 15

Visual disturbance

Question 16

Rhokinase inhibitor

Answer 16

Fasudil

Question 17

Role of Rock

Answer 17

ROCK vasoconstriction and cardiac remodelling

Question 18

Fasudil usage

Answer 18

Angina and cerebral vasospasm