Acute Heart Failure Treatment

Question 1

Aim

Answer 1

Dec congestive symptom

Inc contractility

Question 2

Diuretics in ahf

Answer 2

Dec preload and congestion

Question 3

Diuretics preferred ahf

Answer 3

Loop - furosemide bumetanide

Question 4

Pulmo edema use of diuretic ahf

Answer 4

Venodilation

Question 5

Tolerance for diuretics ahf

Answer 5

Use thiazide or spironolactone along with it

Question 6

Only thiazide that dec mortality ahf

Answer 6

Spironolactone

Question 7

Intro pic drugs used for short term management in ahf

Answer 7

DONUTAMINE
DOPAMINE
INODILATORS
CARDIAC GLYCOSIDES

Question 8

DObUTAMINE

Answer 8

Selective beta 1 ago
Hence inc cardiac contractions
Iv infusions
Half life 2 min

Question 9

Dopamine action

Answer 9

B and a receptors based on conc
1-2 renal vasodilation
2-10 beta 1 stim
Grtr than 10 vasoconstriction of vesses

Question 10

Cardiac glycosides content

Answer 10

Sugar, non sugar moiety

Question 11

Ex of cardiac glycosides

Answer 11

Digoxin
Digitoxin
Strophanthin
Ouabain

Question 12

Cardiac glycosides

Answer 12

Don’t change mortality

Question 13

Cardiac glycosides used in which heat conditions

Answer 13

Acute chf
Aflutter
Afib
Psvt

Question 14

Only in Inotropic drug given orally

Answer 14

Digoxin

Question 15

Digitalis time off action

Answer 15

Slow acting drug

Question 16

Afib moa of digitalis

Answer 16

Inc refractoriness if av nodal pathway

Question 17

Mc and characteristic rhythmic effect of digitalis

Answer 17

Ventricular bigrminy / trigeminy

Question 18

Mild digitalis toxicity

Answer 18

K but if major then lignocaine

Question 19

For bradyarryhtmia

Answer 19

Atropine

Question 20

Astaroxamine moa

Answer 20

Inhibits nak and inc ca entry as well

Question 21

Digoxin contraindicated in

Answer 21

CONTRAINDICATED IN Weak HEART

CARDITIS
INC CA
WPw
Hypokalemia
Elderly
Av block
Renal failure
Thyroid

Question 22

When can digitalis be used in mi

Answer 22

Only when it is associated with heart failure and afib

Question 23

Digitalis and wpw

Answer 23

Contraindicated

Question 24

Digitalis and ccb and quinidine

Answer 24

Shouldn’t be given to gather since digitalis toxicity occurs

Question 25

Digitalis side effects

Answer 25

Gynecomastia yellow vision
Ventricular bigeminy
Non paroxysmal supraventricular tachycardia

Question 26

Inotropic drugs not used in

Answer 26

Right heart failure

Question 27

Right heart failure mostly uses

Answer 27

Diuretics and vasodilators

Question 28

Right heart failure and inodilators

Answer 28

Can be used. Since they have both properties

They are pd inhibitors

Question 29

Inodilator examples

Answer 29

Inamrinone
Milrinone
Enoximone
Vesnarinone

Question 30

Inamrinone is

Answer 30

Inodilator

Question 31

Milrinone is

Answer 31

Inodilator

Question 32

Inodilator action

Answer 32

Pde 3 inhibitor inc camp

Question 33

Indications of inodilators

Answer 33

Short term use in sever refractory chf

Question 34

Inamrinone side effect

Answer 34

Thrombocytopenia

Question 35

Why is Milrinone preferred over enamrinone

Answer 35

Doesn’t cause thrombocytopenia

Question 36

Levosimendan use

Answer 36

Sensitises myocardium to ca by binding to troponin c

Opens k channels to cause vasodilation

Question 37

Bnp medical drug name

Answer 37

Nesiritide

Question 38

Bnp helps in differentiating

Answer 38

Pulmonary and cardiac dyspnoea

Question 39

Indication of nesiritide usage

Answer 39

Acute chf and dyspnoea at rest

Question 40

Limiting factor of nesiritide

Answer 40

Neutral endopeptidase

Question 41

Neutral endopeptidase inhibitor

Answer 41

Sacubitril

Question 42

Sacubitril is used in combo with which drug

Answer 42

Valsartan