Part two - transplantation Flashcards
Define isograft
Organ or tissue from genetically identical twin
Define allograft
Organ or tissue transplanted from one individual to another
Define xenograft
Graft between different species
Define orthotopic graft
Graft palced in normal anatomical site
Heterotopic graft
Graft placed in site different from where it is usually located
Alloantigen
Transplant antigen
Alloantibody
Transplant antibody
HLA
Human leukocyte antigen - the main trigger of graft rejection
ABO blood groups and transplantation
A -> can receive A or O
B -> can receive B or O
AB -> can receive AB only
O -> can receive O only
Child-Pugh score and operative mortality
A - 10%
B - 30%
C - 60%
Child-Pugh score and survival
A - 80% / 40% / 30%
B - 60% / 20% / 10%
C - 40% / 20% / 0%
For 1-, 5- and 10-year survival
MELD score
The Model of End-stage Liver Disease
Uses age, creatinine, bilirubin, INR and frequency of haemodialysis into a logarithm formula