PART II Basic Flashcards
List the visual field defects associated with glaucoma:
Nasal step
Paracentral depressions
Arcuate defects
Ring scotoma
tunnel vision with central vision sparing
Steroid response raised IOP usually develops over
2-4 weeks
With intensive courses of topical steroid, raised IOP has been reported to occur over hours, but this is more rare. The IOP usually returns to normal after cessation of steroid but this is not universal.
phacoanaphylactic (phaco-antigenic) glaucoma
caused by an auto-immune granulomatous reaction to lens proteins in an eye with a ruptured capsule.
Phacolytic glaucoma
caused by high molecular weight lens proteins which have leaked through an intact capsule of a hypermature cataract and have blocked the trabecular meshwork. Findings include an open irido-corneal angle, corneal oedema and pseudo-hypopyon (lens material and macrophages).
Phacomorphic glaucoma
caused by secondary angle closure due to an intumescent lens and will demonstrate closed irido-corneal angles on gonioscopy.
Generalized myasthenia gravis (auto-antibody)
antibodies binding acetylcholine receptors
Anti-ACh receptor antibodies are found in 90% of patients with generalised myasthenia gravis.
Acanthamoeba keratitis Findings
small epithelial cysts (early)
a ring infiltrate corneal ulcer
suppurative ulceration with hypopyon (late)
prominent corneal nerves, because of perineural infiltration
grow best on non-nutrient agar overlaid with E. coli
confocal microscopy can be used to visualize the organisms in vivo
Acanthamoeba keratitis is characterised by: (clinical)
pain out of proportion to the clinical exam
risk factors:
contact lenses
cleaning contact lenses in tap water
trauma
direct exposure to soil
exposure to standing water (well water, ponds, lakes)
Acanthamoeba keratitis Treatment
polyhexamethylene biguanide
Cataract extraction in patients with pseudoexfoliation syndrome (challenging factors)
- incomplete pupillary dilation
- abnormally weak lens zonules
- a brittle anterior capsule
marginal keratitis
inflammatory reaction against staphylococcal antigens
Staph epidermis is most frequently associated with hypersensitivity marginal keratitis
most common cause of hyperacute purulent conjunctivitis is:
Neisseria gonorrhoeae conjunctivitis
Neisseria gonorrhoeae is the most common cause of hyperacute purulent conjunctivitis. If untreated, it can rapidly progress to corneal ulceration and perforation, since Neisseria gonorrhoeae can progress through intact corneal epithelium to cause ulceration, perforation and endophthalmitis.
salt and pepper appearance of fundus
TB
RP sine pigment
myotonic dystrophy
Ocular TB feature
uveitis
most common allergic features - phylectular keratoconjunctivitis
keratoconus most common refractive error
myopia with irregular astigmatism