part 4 Flashcards
__________ transmit signals by a mechanism whose beginning is similar to the action of acetylcholine, that is, they are absorbed on a receptor.
Monoamine messengers
Give examples of monamine messengers
-Dopamine
-Serotonin
-Epinephrine
-Histamine
A cascade of events through
which the signal of a neurotransmitter or hormone delivered to its receptor is
carried inside the target cell and amplified into many signals
Signal Transduction
give me effects of signal transduction
- protein modifications
- enzyme activation
- the opening of membrane
channels
what does manufacturing of cAMP result to?
electrical signals
What produces cAMP?
adenylate cyclase
What happens to Adenylate Cyclase when the neurotransmitter or the hormone separates from the receptor
stops the synthesis of cAMP
when the neurotransmitter or the hormone separates from the receptor, what destroys the cAMP that is already produced?
Phosphodiesterase
The _________ transduction signaling is not limited to monoamine
messengers.
G-protein- adenylate-cylase
give examples of neurotransmitters and hormones that uses the signalling path other then monoamine messengers
- glucagon
- vasopressin
- luteinizing hormone
- enkephalins
- P-protein.
In Adrenergic messengers, how does the body deactivate monoamines
Via Oxidation to an aldehyde
What enzyme catalyses the oxidation of an aldehyde in the deactivation of monoamines
Monoamine oxidases (MAOs)
What process is when Histamine is synthesized?
Decarboxylation
Histamine is synthesised from what?
His (Histidine)
This histamine receptor is involved in allergic reactions, and inflammation. It is found in the respiratory system
H1 Receptors