part 3 Flashcards
Because ACh enables ion channels to open and propagate signals, the channels themselves are called __________.
ligand-gated ion channels
nicotine in low doses is a _______
stimulant
nicotine does what as a stimulant?
an agonist. enhancing the receptors response
nicotine in high doses is a _______
deppresant
nicotine does what as a depressant?
an antagonist. it blocks the receptors.
What happens when ACh is not released or there is an impairment of synthesis
ACh concentration is reduced and Nerve transmission is impaired
what are chemicals in the brain that promote the transmission of signals between nerve cells
Excitatory neurotransmitters
Give examples of excitatory neurotransmitters
-Glu
-Asp
-Cys
Are chemicals that reduce neurotransmission
Inhibitory neurotransmitters
Give examples of inhibitory neurotransmitters
-Glu
-Taurine
-B-Alanine
-Y-Aminobutyric Acid
How many subclasses of receptors does Glu have
five
The gate of the Glu ion channel is closed by what ?
Mg2+ ion
What type of ion channel is the NMDA receptor?
ligand-gated ion channel
what is the best known receptor of glu
N-methyl-D-aspartate (NMDA) receptor.
Glu is removed by _______, which is facilitated by __________
- Reuptake
- Transporter molecules