Part 3 Flashcards

1
Q

the major underlying cause of CVD is due to

A

ischemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the direct effect of increased SNS stimulation on coronary vascular smooth muscle

A

thromboxane A2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is most effective at preventing abnormal platelet plugs from blocking the vessel lumen

A

prostacyclin from endothelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what substance acts as an anticoagulant by enhancing the action of antithrombin III

A

heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is associated with most of the actual tissue damage following a MI

A

free radial damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what effect does aspirin have on the production of thromboxane A2

A

blocks production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

why does hemophilia occur almost exclusively in males

A

sex-linked on the X chromosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

coumarin acts as an anticoagulant through its action on what organ

A

liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what cardiac muscle cells contract weakly and have fewer fibrils

A

purkinje fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what statement concerning intercalated discs is not true

A

is a major source of stored Ca

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what best describes the change in membrane permeability for K

A

decreases at the onset of depolarization, decreases during repolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

if ion channels are closed, an ion will be at its Nernst equilibrium potential

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

digitalis binds to and inhibits

A

Na/K pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

a longer relative refractory period in the AV nose and bundle serves what function

A

protects the ventricles from supraventricular arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the normal range for ejection fraction

A

50-60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

typically, what percentage of blood from the atria to ventricle moves passively

A

70-75%

17
Q

hyperactivity of the SNS may impede what process

A

collateralization

18
Q

what increases during the first half of ejection

A

LV volume

19
Q

in an isolated heart lung preparation, an increase in venous return within physiologic limits will cause what response

A

increase in HR and stroke volume

20
Q

what would create only a diastolic murmur

A

aortic insufficiency

21
Q

elevation of what is an independent risk factor for CVD

A

homocysteine

22
Q

thyroxine is a positive inotropic substance

A

true

23
Q

a right axis deviation of the mean electrical axis may be due to

A

right bundle branch block

24
Q

the major function of the AV node is

A

delay the wave of depolarization from entry into the ventricles

25
Q

on an EKG, you notice a prolonged PR interval. nothing else is unusual. what can you conclude

A

first degree AV block

26
Q

ischemia is associated with what changes on an EKG

A

inverted T wave

27
Q

damaged myocardial cells are in what abnormal state electrically

A

depolarized

28
Q

if the QRS in lead I is -10 mv and the QRS in lead AvF is +10 mv, the mean electrical axis is closest to

A

+135 deg-> lower left quadrant