Part 3 Flashcards
the major underlying cause of CVD is due to
ischemia
what is the direct effect of increased SNS stimulation on coronary vascular smooth muscle
thromboxane A2
what is most effective at preventing abnormal platelet plugs from blocking the vessel lumen
prostacyclin from endothelium
what substance acts as an anticoagulant by enhancing the action of antithrombin III
heparin
what is associated with most of the actual tissue damage following a MI
free radial damage
what effect does aspirin have on the production of thromboxane A2
blocks production
why does hemophilia occur almost exclusively in males
sex-linked on the X chromosome
coumarin acts as an anticoagulant through its action on what organ
liver
what cardiac muscle cells contract weakly and have fewer fibrils
purkinje fibers
what statement concerning intercalated discs is not true
is a major source of stored Ca
what best describes the change in membrane permeability for K
decreases at the onset of depolarization, decreases during repolarization
if ion channels are closed, an ion will be at its Nernst equilibrium potential
true
digitalis binds to and inhibits
Na/K pump
a longer relative refractory period in the AV nose and bundle serves what function
protects the ventricles from supraventricular arrhythmias
what is the normal range for ejection fraction
50-60
typically, what percentage of blood from the atria to ventricle moves passively
70-75%
hyperactivity of the SNS may impede what process
collateralization
what increases during the first half of ejection
LV volume
in an isolated heart lung preparation, an increase in venous return within physiologic limits will cause what response
increase in HR and stroke volume
what would create only a diastolic murmur
aortic insufficiency
elevation of what is an independent risk factor for CVD
homocysteine
thyroxine is a positive inotropic substance
true
a right axis deviation of the mean electrical axis may be due to
right bundle branch block
the major function of the AV node is
delay the wave of depolarization from entry into the ventricles
on an EKG, you notice a prolonged PR interval. nothing else is unusual. what can you conclude
first degree AV block
ischemia is associated with what changes on an EKG
inverted T wave
damaged myocardial cells are in what abnormal state electrically
depolarized
if the QRS in lead I is -10 mv and the QRS in lead AvF is +10 mv, the mean electrical axis is closest to
+135 deg-> lower left quadrant
