Part 2 Flashcards

1
Q

platelets help in the repair of a damaged vessel wall by releasing what substance

A

growth factor

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2
Q

normally what prevents platelets from adhering to a normal endothelium

A

glycoproteins in the platelet wall

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3
Q

what function does thromboxane A2 play in activation of platelets

A

potentates platelet granule release

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4
Q

what is not a function of prostacyclin

A

acts as a vasoconstrictor

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5
Q

how does aspirin block the formation of both thromboxane A2 and prostacyclin production

A

blocks FA cyclooxygenase

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6
Q

which is capable of dissolving or liquifying a blood clot

A

plasmin

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7
Q

how does dicumarol function as an anticoagulant

A

inhibits liver clotting factors

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8
Q

what is the cause of a repercussion injury in the myocardium

A

free radical damage

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9
Q

what effect will occur if fast Na channels in a cardiac cell is blocked

A

the cell will depolarize at a slower rate

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10
Q

if EDV is 150 mL and ESV is 100 mL, what is the ejection fraction

A

33%

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11
Q

during isovolumic contraction to the left-sided valves are in what state

A

mitral closed, aortic open

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12
Q

most of the blood ejected from the ventricles is ejected in the first half of the ejection phase

A

true

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13
Q

what percent of blood that moves from atria to ventricles is actively pumped by the atria

A

25%

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14
Q

what is the major function of the AV node

A

delay the wave of depolarization from entering the ventricles

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15
Q

the stable resting polarized state in a typical cardiac muscle cell is due to

A

K at its Nernst equilibrium and an impermeable membrane to Na and Ca

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16
Q

under resting conditions, what % of oxygen is being extracted fro the arterial blood that is perfusing the myocardium

A

about 70%

17
Q

how does digitalis act to increase strength of contraction

A

decreases function of calcium exchange protein

18
Q

the first heart sound is associated with what event

A

closure of the AV valves

19
Q

a machinery murmur heard throughout the entire cardiac cycle is likely associated with what condition

A

patent ductus arteriosis

20
Q

a machinery murmur heard throughout the entire cardiac cycle is likely associated with what condition

A

patent ductus arteriosis

21
Q

a diastolic murmur would likely be associated with what condition

A

aortic insufficiency

22
Q

as systemic arterial blood pressure is increased, what happens to the strength of left ventricular contraction if the ANS effect on the heart is blocked

A

decrease in LV contractile strength

23
Q

what is the function of the papillary muscles in the wall of the RVs when they contract

A

prevents prolapse of the tricuspid valve

24
Q

which are dependent on ANS function

A

pressure induced homeometric autoregulation

25
Q

how does the stretch on the SA nose increase HR

A

by increasing membrane permeability to Na/Ca

26
Q

increase EC K levels 2-3X above normal will have what effect on myocardial performance

A

extreme weakness and flaccidity

27
Q

what effect would a fever of 100 degrees F have on resting HR

A

increased HR 10 bpm

28
Q

most of the energy consumed by the heart is associated with

A

the production of heat

29
Q

the principal energy source for cardiac output is

A

FAs

30
Q

increased stretch on the ventricular myocardium at the end of diastole is associated with

A

increase calcium influx

31
Q

PSNS activation can cause inhibition of NE release presynaptically

A

true

32
Q

what is most responsible for the all or none response of the cardiac myocardium

A

intercalated discs

33
Q

what is not a feature of the SA node

A

stable resting polarized state

34
Q

in a third degree AV block, what is true

A

the atria and ventricles are beating independently

35
Q

describe atrial repolarization

A

buried in the QRS complex

36
Q

what normally prevents cells other than SA nodal cells from firing spontaneously

A

purkinje cells

37
Q

if the net deflection of the QRS complex in lead I is negative 5 mm, and the net deflection in lead AvF is positive 5 mm, what can you say about the mean electrical axis

A

right axis deviation