Part 2 Flashcards
What is the possible late complication of measles infection (several years after the acute infection)?
SSPE – subacute sclerosing panencephalitis
What is the portal of entry of the viruses belonging to Paramyxoviridae?
Respiratory tract – aerosol infection
Which virus is the most common cause of severe viral lower respiratory tract infections in infants and small children?
respiratory syncitial virus (RSV)
What are the possible complications of adulthood mumps virus infection? Specify at least 2 of them!
Orchitis, meningitis, pancreatitis
What is the route of infection of rabies virus? How does rabies virus spread in the infected body?
By the bite of a rabid animal, (rarely by infectious aerosol) spread of the virus in the host – along the axons
What medication does a person need after exposure to rabies virus?
Active immunization – human diploid cell vaccine (killed virus) and passive immunization – rabies immune globulin
What is the portal of entry of polioviruses? Which areas of the central nervous system are affected by poliovirus infection?
oropharynx and gastrointestinal tract
damage in motor neurons in the anterior horn of the spinal cord + brain stem
Which human viruses belong to the Enterovirus genus?
Polioviruses, coxsackie viruses, echoviruses, enteroviruses 68 - 71
Mention at least 4 diseases caused by Coxsackie viruses!
febrile rashes, herpangina, myocarditis, pericarditis, meningitis, pleurodynia, hand-foot-and-mouth disease
What disease do rotaviruses cause? At which age?
gastroenteritis in young children
List the 3 antigens of hepatitis B virus against which antibodies may develop during or after the acute phase of infection?
HBsAg, HBeAg, HBcAg
Which hepatitis B-specific antibody is almost never present in chronic hepatitis?
Anti-Hbs
What are the main modes of transmission of HBV (hepatitis B virus) infection?
Sexual contact; perinatally from mother to newborn; by blood or blood products
What are the 2 serological markers that are necessary and sufficient to prove acute hepatitis B virus infection?
HBsAg, Anti-HBc IgM
Describe the active and passive prophylaxis against hepatitis B!
active immunization: recombinant HBsAg vaccine
passive immunization: HBIG (hepatitis B immune globulin)