Part 2

Question 1

Treatment for quick relief of asthma (acute cases)

Answer 1

SABA (salbutamol or albuterol)
Systemic corticosteroids (prednisone, Prednisolone , Methylprednisolone)
Anticholinergics (Ipratropium)

Question 2

Side effects of SABA

Answer 2

Tremor, Tachycardia, Hypokalemia

Question 3

1st line DOC in chronic asthma?

Answer 3

Inhaled corticosteroids

Beclomethasone, Fluticasone, Mometasone, Budesonide

Question 4

Side effect of inhaled corticosteroids

Answer 4

Oropharyngeal candidiasis

Question 5

LABA drugs

Answer 5

Formoterol Salmeterol

Question 6

Long acting Anti-cholinergic drug?

Answer 6

Tiotropium

Question 7

Drug’s contraindicated in asthmatic patients

Answer 7

Beta Blockers, LABA alone , Aspirin

Question 8

Mineral corticosteroids

Answer 8

Fludrocortisone, Deoxy-corticosteroid, Aldosterone

Question 9

Most potent corticosteroid

Answer 9

Dexamethasone

Question 10

Least potent corticosteroid

Answer 10

Hydrocortisone

Question 11

What’s the maximum Prednisone dose in asthmatic patient

Answer 11

60 mg/kg

Question 12

Function of alpha-1-antitrypsin in lung

Answer 12

Protect the lungs from neutrophils elastase & enhance alveolar exchange

Question 13

Indapamide used in

Answer 13

Pulmonary edema and essential hypertension

Question 14

MOA of Cromolyn

Answer 14

Mast cell stabilizer

Question 15

Patient with respiratory depression from anesthesia

Answer 15

Picrotoxin

Question 16

Hepatotoxicity of paracetamol due to ?

Answer 16

Glutathione depletion

Question 17

Why is Lactulose used in Hepatic Encephalopathy?

Answer 17

To decrease ammonia levels in blood

Question 18

Hb1 genotype hepatic patient treatment?

Answer 18

Interferon , Ribavirin

Question 19

Fat, soluble, vitamins, important for liver

Answer 19

Vit A,D,E,K

Question 20

Precursor of bile?

Answer 20

Cholesterol

Question 21

Vitamins involved in fatty acids synthesis

Answer 21

B5 B3 B2

Question 22

Neuromuscular blocker used in renal or hepatic failure

Answer 22

Atracurim

Question 23

When a patient has high amylase+lipase it’s called?

Answer 23

Pancreatitis

Question 24

High liver enzyme and normal bilirubin?(what is it called)

Answer 24

Cirrhosis

Question 25

High liver enzyme and high bilirubin?(what is it called)

Answer 25

Stenosis

Question 26

Flow of bile Decreased or Blocked ( high Bilirubin)

Answer 26

Cholestasis

Question 27

Chloramphenicol liver inhibitor MOA?

Answer 27

Decrease metabolism and increase response

Question 28

Hepatotoxicity drug should be discontinued if?

Answer 28

LFT > 3 folds than the upper limit

Question 29

Nucleoside/Reverse transcriptase inhibitors (NRTI) contraindicated in which conditions?

Answer 29

Lactic acidosis, Sever hepatomegaly with stenosis, HBV exacerbation

Question 30

Why is NAPQI produced?

Answer 30

Due to paracetamol oxidation

Question 31

Detoxification of NAPQI

Answer 31

Glutathione conjugation

Question 32

Precursor of Vit D?

Answer 32

7 DHC (Dihydrocholestarol)

Question 33

GFR is measured by?

Answer 33

Inulin

Question 34

In healthy kidney protein binding and albumin should not pass the filter True or false?

Answer 34

True

Question 35

4 indications for dialysis?

Answer 35

High potassium level Overload and no filtration Acidosis Uremia ( high uric acid in blood)

Question 36

Kidney failure diuretic DOC?

Answer 36

Loop diuretics ( Furosemide) Because it decreases the potassium

Question 37

Treatment of kidney failure + Hyperkalemia

Answer 37

Calcium gluconate or CaCl2

Question 38

Anticoagulant with dialysis

Answer 38

Heparin

Question 39

Drug’s contraindicated in kidney failure

Answer 39

Aminoglycosides , potassium sparing diuretics, Metformin

Question 40

Vit D that is used in CKD

Answer 40

1,25-dihydroxycholecalciferol

Question 41

Treatment of anemia with CKD

Answer 41

Epoiten

Question 42

Anemia in CKD with iron deficiency treatment

Answer 42

Darbepoetin

Question 43

Patient on dialysis and has anemia , he is taking Epoetin, hemoglobin level should be?

Answer 43

Less than 11 If it increases more than 11 it will cause cardiovascular disease

Question 44

Patient on dialysis and taking Sevelmer and is feeling face numbness what’s the reason?

Answer 44

Sevelmer causes hypophospatemia which causes face numbness

Question 45

Normal potassium level?

Answer 45

3.5-5

Question 46

Deficiency of Vit A causes?

Answer 46

Night blindness

Question 47

Deficiency of Vit D causes?

Answer 47

Rickets, Osteomalacia

Question 48

Deficiency of Vit E causes?

Answer 48

Thalassemia, infertility

Question 49

Deficiency of Vit K causes?

Answer 49

Bleeding

Question 50

Deficiency of Vit B1 ( thiamin) causes?

Answer 50

Beri-Beri

Question 51

Deficiency of Vit B2 (Riboflavin) causes?

Answer 51

Ariboflavinosis

Question 52

Deficiency of Vit B3 (Niacin) causes?

Answer 52

Pellagra

Question 53

Deficiency of Vit B5 causes?

Answer 53

Paresthesia

Question 54

Deficiency of Vit B6 causes?

Answer 54

Neurological symptoms

Question 55

Deficiency of Vit B7 causes?

Answer 55

Alopecia , Dermatitis

Question 56

Deficiency of Vit B9 causes?

Answer 56

Megaloblastic anemia, Neutral tube defect

Question 57

Deficiency of Vit B12 causes?

Answer 57

Megaloblastic anemia, pernicious anemia

Question 58

Deficiency of Vit C causes?

Answer 58

Scurvy, ginivitis

Question 59

Unfractionated Heparin has shorter half life which causes?

Answer 59

Heaprin induced thrombocytopenia (HIT)

Question 60

Low molecular weight heparin(Enoxaparin) dose?

Answer 60

1mg/kg/day BID or 1.5mg/kg/day OD If GFR <30 , 1mg/kg/day OD Hip replacement prophylaxis 40mg/day OD

Question 61

Direct thrombin inhibitors ?

Answer 61

Oral : Dabigatran Parental: Argatroban

Question 62

Treatment of heparin induced thrombocytopenia

Answer 62

Arganotroban

Question 63

Direct factor Xa inhibitors?

Answer 63

Oral : Rivaroxaban ,Apixaban Parenteral : Fondaparinux