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Pharma > CYP > Flashcards

CYP Flashcards

1
Q

A person who tests positive for HLA-B*5701 should not use which drug

A

Abacavir

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2
Q

A person who tests positive for HLA-B*5801 should not use which drug

A

Allopurinol

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3
Q

A person who tests positive for HLA-B*1502 should not use which drugs

A

CBZ,OCBZ , Phenytoin, Fosphenytoin

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4
Q

Phenobarbital is an enzyme inducer or inhibitor ?

A

Inducer

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5
Q

Rifampin is an enzyme inducer or inhibitor ?

A

Inducer

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6
Q

Phenytoin is an enzyme inducer or inhibitor ?

A

Inducer ( potent)

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7
Q

Ethanol is an enzyme inducer or inhibitor ?

A

Inducer

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8
Q

CBZ is an enzyme inducer or inhibitor ?

A

Inducer

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9
Q

Allopurinol is an enzyme inducer or inhibitor ?

A

Inhibitor

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10
Q

Chloramphenicol is an enzyme inducer or inhibitor ?

A

Inhibitor

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11
Q

Corticosteroids is an enzyme inducer or inhibitor ?

A

Inhibitors

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12
Q

Cimetidine is an enzyme inducer or inhibitor ?

A

Inhibitor

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13
Q

MAO-Is is an enzyme inducer or inhibitor ?

A

Inhibitors

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14
Q

Erythromycin is an enzyme inducer or inhibitor ?

A

Inhibitor

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15
Q

Ciprofloxacin is an enzyme inducer or inhibitor ?

A

Inhibitor

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16
Q

Drugs that are used for cancer that is HER2 receptor positive (breast cancer)

A

Trastuzumab , Pertuzumab

17
Q

In case of KRAS -ve cancer which drugs may be used

A

Cetuximab , Pantiumumab

18
Q

Thiopurine methyltransferase (TPMT) is an enzyme that breaks down (metabolizes) a class of drugs called?

A

Thiopurines ( Azathioprine)

19
Q

Dihydropyrimidine dehydrogenases (DPD) enzyme helps breakdown which drugs?

A

Capecitabine , Fluorouracil

20
Q

CYP of Clopidogrel

A

CYP2C19

21
Q

CYP of Warfarin

A

CYP2C9

22
Q

CYP of Irinotecan

A

UGU1A1

23
Q

Cyp of Rituximab

A

CD20

Pharma (4 decks)

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