CYP

Question 1

A person who tests positive for HLA-B*5701 should not use which drug

Answer 1

Abacavir

Question 2

A person who tests positive for HLA-B*5801 should not use which drug

Answer 2

Allopurinol

Question 3

A person who tests positive for HLA-B*1502 should not use which drugs

Answer 3

CBZ,OCBZ , Phenytoin, Fosphenytoin

Question 4

Phenobarbital is an enzyme inducer or inhibitor ?

Answer 4

Inducer

Question 5

Rifampin is an enzyme inducer or inhibitor ?

Answer 5

Inducer

Question 6

Phenytoin is an enzyme inducer or inhibitor ?

Answer 6

Inducer ( potent)

Question 7

Ethanol is an enzyme inducer or inhibitor ?

Answer 7

Inducer

Question 8

CBZ is an enzyme inducer or inhibitor ?

Answer 8

Inducer

Question 9

Allopurinol is an enzyme inducer or inhibitor ?

Answer 9

Inhibitor

Question 10

Chloramphenicol is an enzyme inducer or inhibitor ?

Answer 10

Inhibitor

Question 11

Corticosteroids is an enzyme inducer or inhibitor ?

Answer 11

Inhibitors

Question 12

Cimetidine is an enzyme inducer or inhibitor ?

Answer 12

Inhibitor

Question 13

MAO-Is is an enzyme inducer or inhibitor ?

Answer 13

Inhibitors

Question 14

Erythromycin is an enzyme inducer or inhibitor ?

Answer 14

Inhibitor

Question 15

Ciprofloxacin is an enzyme inducer or inhibitor ?

Answer 15

Inhibitor

Question 16

Drugs that are used for cancer that is HER2 receptor positive (breast cancer)

Answer 16

Trastuzumab , Pertuzumab

Question 17

In case of KRAS -ve cancer which drugs may be used

Answer 17

Cetuximab , Pantiumumab

Question 18

Thiopurine methyltransferase (TPMT) is an enzyme that breaks down (metabolizes) a class of drugs called?

Answer 18

Thiopurines ( Azathioprine)

Question 19

Dihydropyrimidine dehydrogenases (DPD) enzyme helps breakdown which drugs?

Answer 19

Capecitabine , Fluorouracil

Question 20

CYP of Clopidogrel

Answer 20

CYP2C19

Question 21

CYP of Warfarin

Answer 21

CYP2C9

Question 22

CYP of Irinotecan

Answer 22

UGU1A1

Question 23

Cyp of Rituximab

Answer 23

CD20