PARKINSONS DISEASE

Question 1

Parkinsons’ affects the B.S , a group of structures that help coordinate movement.

Answer 1

BASAL GANGLIA

Question 2

It is a progressive neurological disorder that affects MOVEMENT.

Answer 2

Parkinson’s disease

Question 3

What causes Parkinsons’s disease?

Answer 3

It primarily results from the DEGENATION OF DOPAMINE- PRODUCING NEURONS IN THE substantia nigra

Question 4

A region of the brain that plays a critical role in CONTROLLING MOTOR FUNCTION.

Answer 4

Substantia Nigra

Question 5

_______ is essential for smooth, coordinated muscle movements so its loss leads the chara teristic symptoms of PD.

Answer 5

DOPAMINE

Question 6

It produces dopamine

Answer 6

Substantia Nigra

Question 7

Parkinsons affects autonomic nervous system structures, leading to symproms beyond motor control, such as changes in

Answer 7

Bp, hr, and digestive function

Question 8

The symptoms of Parkinson’s Disease can be divided into

Answer 8

MOTOR AND NON- MOTOR

Question 9

Motor Symptoms of PD

Answer 9

1. Tremor
2. Rigidity
3. Bradykinesia
4. Postural Instability

Question 10

Non - Motor Symptoms

Answer 10

1. Cognitive Decline
2. Mood Disorders
3. Autonomic Dysfunctiom
4. Sleep Disorders
5. Loss of Smell

Question 11

Motor symptoms - affect movent and control of muscles.

Answer 11

Non- Motor - affect other parts of the body and mind

Question 12

Neurodegenerative condition resulting from loss of dopaminergic neurons in the brain,characterized by associated motor symptoms

Answer 12

PARKINSON’S DISEASE

Question 13

Progressive , irreversible loss of neurons

Answer 13

NEURODEGENERATIVE

Question 14

Pathophysiology of PD

Answer 14

● motor signals generated by CEREBRAL CORTEX
● Travel along Motor Pathways
● Producing Movement

Question 15

Regulate motor signalling

Answer 15

Basal Ganglia

Question 16

What part of the brain is primarily affected in Parkinson’s Disease?

Answer 16

Substantia Nigra

Question 17

Which neurotransmitter is most significantly reduced in PD?

Answer 17

Dopamine

Question 18

What are Lewy Bodies?

Answer 18

Lewy bodies are clumps of abnormal protein found inside neurons and their presence is a hallmark of Parkinson’s disease

Question 19

How much dopamine -producing neurons in the substantia nigra are typically lost before motor symptoms appear kn Parkinsons’s disease?

Answer 19

Approx 60 - 80 %

Question 20

How does the loss of dopamine affect the basal ganglia

Answer 20

It causes overactivity in some areas and underactivity in others

Question 21

Loss of smell ( anosmia ) can be an early symptom of Parkinsons Diseasez often occuring before the more classic motor symptoms develop.

Answer 21

EARLY SYMPTOMS OF PD

Question 22

Refers to slowness of movement , which is a hallamrk symptoms of PD

Answer 22

BradyKinesia

Question 23

What type of symptoms are tremors in the PD ?

Answer 23

MOTOR SYMPTOMA

Question 24

SHAKING of one hand when at rest

Answer 24

Tremor ( Motor Symptom )

Question 25

Antiviral ( Generic ) treatment of IDIOPATHIC and Drug- induced Parkinsonism in adults.

Answer 25

AMANTADINE

Question 26

Drug of choice for treatment of Focal SEIZURES AND TONIC-CLONIC SEIZURES; TREATMENT FOR TRIGEMINAK NEURALGIA, BIPOLAR DISORDER

Answer 26

CARBAMAZEPINE

Question 27

Treatment of Depression, OCDs, social anxiety disorder, PTSD, panic disorders , PMDD

Answer 27

SERTRALINE ( ZOLOFT)