Parkinson's Pharm

Question 1

• One is concerted to dopamine, the other prevents the breakdown of dopamine
• AE: Orthostatic hypotension
• Avoid high protein diets

Answer 1

Levodopa-Carbidopa (Sinemet)

Question 2

• Don’t use with St. John’s wart

- Avoid tyramine containing products (like cured meats/cheeses)

Answer 2

Selegiline

Question 3

Inhibits pathway which degrades levodopa

Used as an adjuvant

Answer 3

Tolcapone

Question 4

-Enhances coordinated motor mov’ts by activating postysynaptic dopamine receptors

Answer 4

Ergot derivatives (Bromocriptine)

Question 5

Block nerve impulses in control muscles of body. Decrease Ach levels more closely to match decreasing levels of PD

Answer 5

Anticholinergics