parkinson's disease Flashcards
1
Q
what is it
A
neuro-degenerative disease which results from progresive death of dopaminergic neurons
2
Q
pt prep
A
withold parkinson meds for 12 hours prior
-premedicate wuth 150 mg carbidopa i hr prior to inj of f18 fluorodopa
3
Q
carbidopa prevents body from
A
breakdown of fluorodopa into dopamie which cannot cross BBB
4
Q
putamen=
A
comma
5
Q
f-18 fluoro-DOPA can see
A
a decrease in putamen of basal ganglia
6
Q
f-18 fdg can see a decease
A
in caudate of basal ganglia
7
Q
disadv of dopa
A
complex procedure to prep and synthetic yields are poor