estrogen receptor imaging

Question 1

f-18 fluoroestradiol

Answer 1

a synthetic estrogen analog which is take up into estrogen receptor cells

Question 2

breast cx =

Answer 2

positive estrogen receptors

Question 3

indicated for

Answer 3

ER+ lesions in patients with recurrent or metastatic breast cancer

Question 4

froedtert doesnt use bc

Answer 4

only shows estrogen positive

Question 5

normal distribution

Answer 5

hepatobiliary system, sm and lg intestines, heart wall, blood, kidneys, uterus and bladder

Question 6

what may reduce the uptake of f-18 fluoroestradiol

Answer 6

ER modulators and down regulators block ER thus reducing uptake

Question 7

pt prep

Answer 7

hydrate prior to and after inj and void freq first few hours to avoid excess rad burden

Question 8

dose

Answer 8

3-6 mCi IV over 1-2 min

Question 9

what time after inj to scan

Answer 9

80 min

Question 10

time range to scan

Answer 10

20-80 min

Question 11

scan where

Answer 11

skull base to mid thigh

Question 12

can ER+ cancer cells be other places of the body

Answer 12

yes like ovaries and uterus

Question 13

avoid breast feeding for _____

Answer 13

4 hrs after injection

Question 14

what percent of inj dose remains after 2 hours

Answer 14

5%