Parkinson's Flashcards
which pathway facilitates movement?
direct
which pathway inhibit movement?
indirect
Name 2 medications for parkinson
levo dopa and carbidopa
why do you typically use levo dopa and carbidopa togeher?
prevent l dopa conversion prior to entering the brain
What does dopamine medication help with in parkinsons
bradykinesia/rigidity
what is parkinsons meds not as effective for
trempr and postural instability
side effects of parkinsons meds
DA receptors lose responsiveness
involuntary movements (dyskinesia)
On off phenomenon (on becomes shorter and shorter)
a precursor of dopamine (meds)
L dopa
combination of levodopa and carbidopa(meds)
sinemet
important dosage insrtuction
30 mins before bed
not right before bed
consistent timing is important
Common medication side effects
orthostatic hypotension
dyskinesia
confusion/memory loss
hallucinations (scary things)
HA, agitation, psychosis
hallmarks of PD
resting tremor
akinesia
rigidity
postural instability
TRAP
what is usually the first sign of PD
tremor
what is cogwheel / lead pipe rigidity?
cogwheel : rigidity over tremor
lead pipe–all aspects of movement are difficult (both directions)
Bradykinesia testing
rapid alternating movements (finger tapping, open close fist, pronation supination, toe typing)
BIG fast movements
look for: change in speed and amplitude
Observation/testing for tremor
resting – hands
postural tremor – shoulders flexed at 90 elbows straight / fingers wide
Kinetic Tremor:
rigidity testing
passive wrist circles, elbow flexion/extension
LE support knee flexion/ext or ankle circles
technique to activation maneuver (if meds are working or subtle)
gait and balance defecit tests
sit to stand
pull test (brisk pull back to see how recover)
gait: symmetry, reduced heel strike/foot clearance. turns, arm swing
common gait issues
increased knee flexion in stance
decreased hip and knee flexion early swing, decreased hip and knee ext in late swing
decreased clearance and pushoff
goot contact w entire foot
decreased trunk and pelvic rotation, armswing asymmetry
decreased stride length/walking speed
ROM and strength deficits in PD
STIFF: decreased trunk ext w thoracic kyphosis, trunk rotation, hip and knee extension
gradual weakening - atrophy of T2 fibers, hypertrophy in T1
weak ankle mm and quads…
non motor features of PD (6)
psych, cognitive disorders, sleep abnormalities, autonomic dysfunction (constipation, ortho hypotension!!!!!!), sensory–olfactory, misc (fatigue weight loss)
SLP issues with PD (3)
motor speech–coordination and weakness (forming words/quiet)
Cognition–repeat phrases, minimize distractions
Dysphagia– swallowing/timing with breathing and swallowing, positioning food in mouth
MSK changes in PD
BOS
everything flexed!
forward head, trunk,m rounded shoulders, kyphosis, down gaze,
short hip flexors/knee flexors, elbow flexors
strength–hip ext/PF…trunk ext
dec trunk pelvic rotation
Cardio pulm function in PD
Ortho Hypotension!
reconditioning
Flexed posture: restricted lung function due to decreased chest expansion (PNEUMONIA!)
4 measures of severity PD
Hoehn and Yahr stages of PD
UPDRS (rating scale)
MDS-UPDRS (movement disorder…rating scale)
PDQ-8 PDQ-39 (participation level)
Which stage of Hoehn & Yahr
tremor in one hand
rigidity
clumsy leg
one side face affected impacting expression
1