Parkinson Flashcards
What symptom if present is in favor por Parkinson disease rather than drug induced parkinsonism?
Tremors at rest
Main drugs that cause Dip?
1.Atypical antipsychotics ( phenothiazines ex chlorpromazine)
2.Haloperidol
others: Metoclopramide, cc bloquers, atypical antipsy, antiepileptic drugs.
What is Parkinson’s disease?
A neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia.
True or False: Parkinson’s disease primarily affects the peripheral nervous system.
False: It primarily affects the central nervous system.
What is the primary pathological feature of Parkinson’s disease?
The loss of dopaminergic neurons in the substantia nigra.
Fill in the blank: The major neurotransmitter affected in Parkinson’s disease is ______.
Dopamine.
What are the cardinal motor symptoms of Parkinson’s disease?
Tremor, rigidity, bradykinesia, and postural instability.
Which age group is most commonly affected by Parkinson’s disease?
Individuals over the age of 60.
What is the role of Lewy bodies in Parkinson’s disease?
They are abnormal aggregates of protein that are found in the brains of patients with Parkinson’s.
True or False: Parkinson’s disease can be diagnosed with a definitive laboratory test.
False: Diagnosis is primarily clinical based on symptoms and medical history.
What is the first-line treatment for motor symptoms of Parkinson’s disease?
Levodopa (L-DOPA) combined with carbidopa.
Multiple choice: Which of the following is NOT a common non-motor symptom of Parkinson’s disease? a) Depression b) Constipation c) Hyperactivity d) Sleep disturbances
c) Hyperactivity.
What is the mechanism of action of dopamine agonists in Parkinson’s disease treatment?
They stimulate dopamine receptors in the brain.
Fill in the blank: The ‘on-off’ phenomenon in Parkinson’s disease refers to ______.
Fluctuations in motor function during treatment.
What is the role of deep brain stimulation in Parkinson’s disease management?
It is a surgical treatment that can help alleviate motor symptoms in advanced cases.
True or False: Parkinson’s disease is a hereditary condition.
False: While genetics can play a role, most cases are sporadic.
What is the name of the scale commonly used to assess the severity of Parkinson’s disease?
The Unified Parkinson’s Disease Rating Scale (UPDRS).
Multiple choice: Which of the following therapies is NOT typically used in Parkinson’s disease? a) Physical therapy b) Occupational therapy c) Chemotherapy d) Speech therapy
c) Chemotherapy.
What is the effect of anticholinergic medications in Parkinson’s disease?
They help reduce tremors and muscle rigidity.
Fill in the blank: The term ‘bradykinesia’ refers to ______.
Slowness of movement.
What are some common psychiatric manifestations of Parkinson’s disease?
Depression, anxiety, and hallucinations.
True or False: Parkinson’s disease can lead to cognitive decline.
True: It can lead to dementia in some patients.
What role does genetic testing play in Parkinson’s disease?
It can identify mutations associated with familial forms of the disease.
