Parasitology Flashcards

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1
Q

What is obligate parasite

A

completely dependent on the host during a segment or all of its life cycle, e.g. Plasmodium spp.

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2
Q

What is facultative parasite

A

exhibits both parasitic and non-parasitic modes of living; hence does not absolutely depend on the parasitic way of life, but is capable of adapting to it if placed on a host. e.g. Naegleria fowleri

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3
Q

What is accidental parasite

A

when a parasite attacks an unnatural host and survives. e.g. Hymenolepis diminuta (rat tapeworm).

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4
Q

What is erratic parasite

A

is one that wanders in to an organ in which it is not usually found. e.g. Entamoeba histolytica in the liver or lung of humans.

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5
Q

What is a zoonotic parasite

A

Zoonotic parasite- primarily infects animals and is transmittable to humans, e.g. Fasciola species

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6
Q

What is Permanent parasite

A

lives in or on its host without leaving it e.g. lice.

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7
Q

What is opportunistic parasite

A

Causes illness when the immune system of organism is impaired. HIVAiIds can cause impairment
E.g. Toxoplasma gondii

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8
Q

What is a paratenic host

A

Host that serves as temporary refuge and vehicle for reaching bad obligate host eg plasmodium in mosquito

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9
Q

What may produce a negative host response and what are he responses

A

physical presence of a parasite and its metabolic waste products can stimulate a negative host response, eg production of alkaline phosphatase, corticosteroids, etc.

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10
Q

What are the two stages of amoeba

A
  • Trophozoite – actively motile feeding stage.

* Cyst – quiescent, resistant, infective stage.

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11
Q

True/false

Parasites in the ‘wrong host’ are in general more pathogenic

A

True

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12
Q

What are the four classes of protozoans

A

Sporozoans(Plasmodium)

Ciliophora( Ciliates)

Mastigophora( Flagellates )

Sardonica (Amoeba)

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13
Q

Pathogenesis if amoeba read

A

Pathogenesis
•Trophozoites divide and produce extensive local necrosis in the large intestine.
•Invasion into the deeper mucosa with extension into the peritoneal cavity may occur.
•This can lead to secondary involvement of other organs, primarily the liver but also the lungs, brain, and heart.
•Extraintestinal amebiasis is associated with trophozoites.
•Amoebasmultiply rapidly in an anaerobic environment, because the trophozites are killed by ambient oxygen concentration.

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14
Q

What is the treatment of amoeba infection in cyst and trophozytes

A
Trophozoites:
•metrondiazole,
•tinidazole
•chloroquine
•Cysts:
•iodoquinol,
•diloxanide furoate,
•paromomycin
•The cysticidal agents are commonly recommended for asymptomatic carriers who handle food for public use
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15
Q

•it is a pear-shaped organism with a central nucleus and four anterior flagella

A

Trychomona

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16
Q

What is the life cycle of truchomona

A

Trophozoite stage only

17
Q

What are heamoflagellates and their egs

A

Live in the blood, lymph & tissue spaces
transmitted by blood-feeding arthropods

Leishmania spp.
Trypanosoma spp

18
Q

What are the two forms of life cycle that Leishmania spp exhibit

A

amastigote (aflagellar) and

•promastigote (flagellated).

19
Q

What transmits heamoflagellates

A

Transmitted by Phlebotomus and Lutzomyia species of sandflies

20
Q

What does L.donovani cause

A

Veseral leishmaniasis

Symptoms (fever, malaise, weight loss, anaemia) and swelling of the spleen, liver, and lymph nodes.

21
Q

What does L. aethiopica cause

A

Cutaneous leishmaniasis

22
Q

What are the drugs for leshmenia diseases

A
Sodium stibogluconate.
• meglumine antimonate
Alternative drugs
•Amphotericin B
•pentamidine
23
Q

What causes African sleeping sickness

A

Trypanosoma brucei gambiense

24
Q

What causes chaga’s disease or American sleeping sickness

A

Trypanosoma cruzi

25
Q

What treatment is used for sleeping sickness

A

Pentamidine
•Melarsoprol
•Suramin

[Nifurtimox is effective for Chaga’s disease only (Trypanosoma cruzi)]

26
Q

What are the four species of malaria, the latest and the deadliest

A

Plasmodium vivax, P. ovale, P. malariae, P. falciparum
•A new (fifth) species has evolved: P. knowlesii
•P. falciparum is the most deadly and dominant species in West Africa.

27
Q

Egs of commmensalism

A

Florals in human body