✅Parasitology Flashcards
Simple life cycle is defined as
Having one host only
Free living organism that passes through the digestive tract without infecting the host
Spurious parasite
Types of hosts. Define each.
Definitive or final host - parasite attains sexual maturity
Intermediate hosts - harbors asexual or larval stages
Paratenic hosts - parasite does not develop further to later stages
Reservoir hosts - allow life cycle to continue and become addl sources of human infections
Types of vectors. Describe each.
Biologic - transmits parasite only after it has completed its development
Mechanical or phoretic vector - transmits only the parasite
E. Histolytica trophozoites secrete ____ which digest cellular material
Cysteine proteases
T. gambiense mechanism if immune evasion
Antigenic variation (surface protein variation)
Example of a facultative parasite
Strongyloides stercoralis
T gambiense evades the immune system by
Antigenic variation
E granulosus evades the immune system by
Carrying blood group antigens
Toxoplasma evades the immune sysem by
Multiplying inside macrophages
E histolytics produces suppressor factor that
Inhibits monocyte movement.
Kingdim protozoa is divided into
Sarcodina
Sporozoa
Mastigophora
Ciliata
Helminths (metazoa) are divided into
Nemathelminthes (roundworms)
Platyhelminthes (flatworms)
- – trematoda (flukes)
- – cestoda (tapeworms)
Movement of entamoeba
Pseudopods
Brownian movement
Infective stage of entamoeba histolytica
Mature cysts
Virulence factors of entamoeba
Lectin - mediates adherence
Amebapores - penetration
Cyseteine proteases
Spectrum of disease of entamoeba
Cyst carrier
Amebic colitis - dysentery without fever
Ameboma - assoc with dysentery
Amebic liver abscess
Most common extraintestinal form of entamoeba
Amebic liver abscess
Morphology of ulcers in amebic colitis
Flask shaped
Treatment of amoeba in cyst carrier state, amebic colitis and amebic liver abscess
Cyst carrier state - diloxanide furoate
Amebic colitis and amebic liver abscess - metronidazole
Add percutaneous drainage for non responders in amebic liver abscess
3 protozoans that can be treated wity metronidazole
Entamoeba
Giardia
Trichomonas
Luminal agents in amoebiasis include
Diloxanide furoate
Iodoquinol
Paromomycin
Protozoan
Old’s man’s face
Falling leaf motility
Giardia lamblia
Infective stage of giardia
Cyst
Diagnostic stage of giardia
Cysts and trophozoites
Most common cause of backpacker’s diarrhea
Giardia lamblia
Main pathophysiology of giardia infection
Malabsorption
Symptoms of giardiasis -acute
Ab pain
Diarrhea
EXCESSIVE FLATUS SMELLING LIKE ROTTEN EGGS
Parasitic cause of Diarrhea In HIV
Cryptosporidium parvum
Infective and diagnostic stage of cryptosporidium parvum
Thick walled oocysts
Urogenital protozoan
Trichomonas vaginalis
Protozoan with no cyst stage
Trichomonas vaginalis
Characteristic transmission of trichomonas
Ping pong transmission
Sexual intercourse
Characteristic cervic in trichomonas
Strawberry cervix
Disease presentation of trichomoniasis
Watery foul smelling greenish vaginal discharge accompanied by itching and burning
Strawberry gallbladder
Cholesterolosis
Berry aneurysms
Investigate for
SAH
ADPKD
COARCTATION
Mulberry molars
Congenital syphilis
Mulberry tumor
Tuberous sclerosis
Blueberry muffin baby
Congenital rubella
CMV
Disseminated neuroblastoma
Grape like vesicles
Hydatidiform mole
Grape like odor
P. aeruginosa
Banana shaped gametocytes
Plasmodium falciparum
Banana shaped left ventricle
Hypertrophic cardiomyopathy
Orange cast skin
Leptospirosis
Orange colonies
N. asteroides
Pear shaped trophozoites
Giardia
Trichomonas
Pear shaped organ
Prostate
How is trichomonas vaginalis treated?
Single dose oral metronidazole 2grams (4 -500mg tab)
Most impt parasitic disease in man
Malaria
Definitive host of plasmodium
Mosquito
Malaria is transmitted by -_____
Anopheles flavirostris minimus
Infective stage of malaria
Sporozoites
Dormant form of plasmodium vivax and ovale in the liver are called
Hypnozoites
To treat hypnozoites, treat with
Primaquine
Malarial schizonts released from the blood
Merozoites
Partial immunity called ____ is seen in individuals who completely recover from falciparum malaria
Preminition