Parasitology Flashcards

1
Q

What is a Parasite?

A

Organisms that Occupies Host + Draws Nutrients Directly From Them

  1. Parasite Offers Nothing to Relationship
  2. Benefits at expense of Host
  3. Arrangement is Neutral/Harmful, never +tive
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2
Q

What Are The 2 Main Parasite Groups?

A

Protozoa:
Single-cell Eukaryotic Micro-organisms
Found in Water, Soil

Helminths:
Multicellular Parasitic Worms
Obligate parasites

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3
Q

What Are The Parasitic Stages?

A

Protozoa

Active: Trophozoite causes disease

Infective: Cyst, a resistant transmissible form, survives for extended time periods

Helminths

Active: (Worms, Larvae) Cause Disease

Infective: (Eggs) a resistant transmissible form, survives for extended time periods

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4
Q

What Is A Parasite Host?

A

An Organism that Provides Nourishment and Shelter

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5
Q

What Are The 2 Types Of Hosts?

A

Definitive Host:

Supports sexually mature, reproducing adult parasite

Intermediate Host:

Supports immature/non-reproductive forms of parasite

Some parasites use definitive host only
Other parasites utilize 1/more Intermediate Host Before Maturing In Definitive Host

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6
Q

What Are The General Characteristics of Protozoa?

A
  1. Unicellular
  2. Eukaryotic (Membrane Bound
    Organelles)
  3. Asexual Reproduction: produces
    Daughter Cells with DNA Identical To
    Parents Protozoan
  4. Forms Cysts (Dormant Form,
    Consumed By Host)
  5. Classified According to Locomotive
    Apparatus
    (Movement with Specialize Structures)
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7
Q

How Do Protozoa obtain Nutrition?

A

Via:

  • Pinocytosis
  • Engulfing
  • Cytosome
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8
Q

List Some Protozoa.

A
  • Amoeba
  • Apicomplexans
  • Ciliates
  • Flagellants
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9
Q

Give An Example of a Medically important Amoeba.

A

Entamoeba Histolytica

  • Causes Amoebiasis
  1. invades intestinal lining, can spread to
    liver
  2. Causes Ulcers, Tissue Destruction,
    Bloody Diarrhea, Abdominal Pain
  3. Mimics Other Diseases (Symptom
    Overlap)
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10
Q

What is Balantidium Coli?

A
  1. Largest protozoan Parasite Of
    Humans
  2. Only Ciliate Pathogenic To Humans
  3. Commonly found In Pigs/Cattle
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11
Q

What Is Giardia Intestinalis?

A

Waterborne Protozoan parasite Causing Giardiasis, Diarrheal Disease

Colonizes Small Intestines of Humans + Animals

2 Forms:

Trophozoite:

Pear Shaped, motile feeding stage with 8 flagella + ventral suction disk

Cyst:

Infectious, dormant stage with protective wall, shed in feces

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12
Q

What Is Toxoplasma Gondii?

A

Obligate Intracellular Protozoan Parasite

Causes Toxoplasmosis

3 Infectious Stages:

Tachyzoites:

Rapidly Dividing, invasive form during acute infection

Bradyzoites:

Slow-Growing, Dormant Form In Tissue Cysts

Oocysts: Environmentally resistant
Spores

Definitive Host: Cats

Intermediate Hosts: Humans, Birds, Rodents, Livestock

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13
Q

What Are the 3 Main Categories Of Helminths?

A

Nematodes (Roundworms)
Cestodes (Tapeworms)
Trematodes (flukes)

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14
Q

What Are The General Characteristics of Nematodes?

A

Eukaryotic/Multicellular Cylindrical Parasites with a Complete Digestive Tract

They are Dioecious (Male + Female)

They Are Transmissional via Ingestion of Eggs or Larval Penetration Through Skin

Undergo 4 Moults + 4 Larval Stages To Reach Adult Stage

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15
Q

Give An example Of a Medically Important NEMATODE.

A

Enterobius Vermicularis (PINWORM):

Nematodes (Roundworm) that use Eggs (Infective Stage) on Human (Definitive Hosts)

Mechanism:

  1. Eggs Ingested Via Contaminated Hands/Food
  2. Eggs Hatch In Small Intestine ➜ Larvae
    Released
  3. Larvae Move ➜ Large Intestine ➜ Mature
    Into Adult Worms
  4. Pinworms Mate In Large intestine
  5. Female Worms Travel + Lay Eggs in Anal
    Region
  6. Egg Hatching ➜ Causes Itching/Irritation
  7. Itching ➜ Eggs Transferred under
    Fingernails, Onto Hands
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16
Q

What Are The general Characteristics Of Cestodes (Tapeworms)?

A
  1. Scolex (Head with Suckers/Hooks to Attach
    To Intestinal Wall)
  2. Tegument: No Digestive System (Nutrient
    Absorption Directly Through Tegument)
  3. Hermaphroditic (Male + Female
    Reproductive Organs)
  4. Require Intermediate Host (Which
    Consumes Eggs)
  5. Segmented
  6. Have Organs
17
Q

Describe Taenia saginata (Beef Tapeworm)

A
  1. Eggs Excreted ➜ Passed In Environment
  2. Embryonated Eggs Ingested By Cattle
  3. Eggs Hatch ➜ Penetrate intestinal Wall
  4. Circulate to Musculature in Cattle
  5. Infection From Undercooked/Infected Beef
18
Q

What Are The General Characteristics Of Trematodes (Flukes)?

A
  1. Flat, Oval/Leaf Shaped
  2. Hermaphroditic
  3. Tegument (Protection, Nutrient Absorption +
    Immune Evasion)
  4. Primitive DS: Actively Digests Host
    Tissues/Blood

Life Cycle Involves:

Multiple Intermediate hosts
Various Sexual + Asexual Development Stages

19
Q

Give An Example Of A Trematode.

A

Fasciola hepatica (Fluke)

  1. Unembryonated eggs passed in feces →
    Released into the environment
  2. Eggs Embryonate In Water (Develop Into
    Miracidia)
  3. Miracidia Hatch In Water → Actively
    Penetrate Snail Tissue (Intermediate Host)
  4. In The Snail:
    • Miracidia → Sporocysts → Rediae →
      Cercariae (asexual reproduction)
  5. Cercariae Exit Snail → Encyst as
    Metacercariae on aquatic vegetation
  6. Definitive host (e.g., sheep, humans) eats
    vegetation
  7. Metacercariae excyst in intestine → Migrate
    To Liver → Develop Into Adult flukes In Bile
    Ducts