Mutations Flashcards

1
Q

What is a Karyotype?

A

The Observed Characteristics of Chromosomes of an individual or species.

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2
Q

What Are Karyotypes Used For?

A
  • To Diagnose Chromosomal Aberrations
    (Abnormalities e.g. Missing/Extra
    Chromosome)
  • To Determine Gender
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3
Q

What Is The Karyotyping Procedure?

A
  1. Sample Collected + Tissue Cultured
  2. Cells Treated with Chemical To Arrest In
    Metaphase
  3. Hypotonic Solution Separates Chromosomes
    (Cause Swelling, Separating + Spreading)
  4. Chromosomes Fixed On Slide
  5. Chromosomes Stained
  6. Cell Photographed, Enlarged + Cut Out
  7. Chromosomes Matched By Banding Patterns
  8. Chromosomes Arranged By Size + Location
    Of Centromere
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4
Q
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5
Q
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