Parasitology Flashcards
Duration of blood phase of p. Malariae
72 hrs
Duration of blood phase of P. Vivax , Ovale,and falciparum
48hrs
Incubation period of P. Falciparum
7-10 days
Prodromal (initial/quotidian signs) of malaria
- Chills
- Fever
- Nausea
- Vomiting
- Diarrhoea
Complications of malaria
- Hypoxic brain injury
Complications of malaria
- Kidney problems which lead to hemoglobinuria, acute renal failure and tubular necrosis.
Complications of malaria
Liver problems leading to hepatosplenomegally, abdominal pain,vomiting of bile etc.
On malaria test kit
T1- P.Falciparum
T2- P.Vivax
Malaria treatment drugsCombination therapies
- Artesunate- Amodiaquine
- Artemether- Lumefantrine
- Dihrdoxyartemisin- Piperaquine
- Sulphurdoxine- Pyrimethamine.
Secondary organs that are engaged during amoebiasis
Liver, lungs, brain, and heart
Must know
Trophozoites of amoeba divide in an anaerobic environment because they are killed by ambient oxygen
Treatment for amoebiasis
Trophozoites
- Metronidazole
- Tinidazole
- Chloroquine
Treatment for amoebiasis
Cyst
- Iodoquinol
- Paromomycin
- Diloxanide furoate
Mastigophora
Genital flagellate
Trichomonas vaginalis
Mastigophora
Hemoflagelates
- Leishmania donovani
- Trypanosoma
Mastigophora
Intestinal
Giardia Lamblia
Transmission of gardia lamblia
Ingestion of infective cyst
Treatment of Gardia
- Metronidazole
- Quinacrine hydrochloride
Trichomonas vaginalis
Life cycle = trophozite only
Trichomonas vaginalis
Treatment
🚇 metronidazole as a single dose fir 1 wk
2. Tinidazole
Leishmania exits in two forms during its life cycle
- Amastigote
- Promastigote
Species of leishmania that transmit leishmaniasis
- Phlebotomus
- Lutzomyia
Reservoir host for leishmaniasis
Wild and domesticated animals, and humans
Drugs for treatment of leishmaniasis
- Sodium stibogluconate
- Melamine antimonate
Alternative drugs - Amphotericin B
- Pentamidine
Hemoflagelates
Both wild and domestic animals serves as reservoir host.
Trypanosoma brucei gambiensis
Found in West 🌍 Africa
Nifurtimox
For treating trypanosoma cruzi