Paramyxoviruses

Question 1

What are the 3 viruses in the category of paramyxovirus?

Answer 1

RSV, hMPV, hPIV

Question 2

What is the microbiology of all three viruses?

Answer 2

Enveloped, non-segmented, negative RNA

Question 3

Are these viruses systemic or do they stay in the respiratory tract?

Answer 3

Stay in respiratory tract

Question 4

What virulence factor plays a role in virus entry and fusion of adjacent cells to form syncytia?

Answer 4

Fusion protein

Question 5

What virulence factor allows binding of hMPV and hPIV to host cells?

Answer 5

HN protein. Cuz hMPV and hPIV must bind to host sialic acid

Question 6

This is the protein to which RSV binds

Answer 6

G protein on GAGs

Question 7

1 cause of pneumonia in infants?

Answer 7

RSV

Question 8

2 cause of pneumonia in infants?

Answer 8

hPIV

Question 9

How do the paramyxoviruses transmit?

Answer 9

Human to human via cough droplets.. Very seasonal (fall and spring)

Question 10

Are RSV infections common in adults too?

Answer 10

yes.. dont think that it only infects kids