Corynebacterium diptheriae Flashcards

1
Q

What is ABCDEF-PP? haha, pee pee

A
A= ADP ribosylation
B= beta-prophage
C= corynebacterium
D= diptheria
E= EF-2 (what diphtheria messes with)
F= EF-2 (elongation factor 2)
P= pseudomembranous 
P= pharyngitis
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2
Q

Mech of diphtheria disease?

A

ADP ribosylation of EF-2 halts protein synthesis

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3
Q

Presentation?

A

NON-IMMUNIZED kid with pseudomembranous pharyngitis

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4
Q

Treatment?

A

Diptheria anti-toxin; penicillin/erythromycin

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5
Q

Can also effect what organs besides pharynx?

A

Brain & heart

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