Corynebacterium diptheriae Flashcards
1
Q
What is ABCDEF-PP? haha, pee pee
A
A= ADP ribosylation B= beta-prophage C= corynebacterium D= diptheria E= EF-2 (what diphtheria messes with) F= EF-2 (elongation factor 2) P= pseudomembranous P= pharyngitis
2
Q
Mech of diphtheria disease?
A
ADP ribosylation of EF-2 halts protein synthesis
3
Q
Presentation?
A
NON-IMMUNIZED kid with pseudomembranous pharyngitis
4
Q
Treatment?
A
Diptheria anti-toxin; penicillin/erythromycin
5
Q
Can also effect what organs besides pharynx?
A
Brain & heart