Papulosquamous Disorders Flashcards
after sore throught
Reactivation of either human herpes virus 7 or human herpes
virus 8.
not contagious
Pityriasis Rosea
Pityriasis rosea course
one
plaque apper (the ‘herald/mother’
plaque) before the others.
It is larger (2–5 cm in diameter)
than later lesions,
and is rounder, redder and
more scaly.
*eruption lasts 2-10w then displaced by hyperpigminted lesions that fade slowly
ddx for Pityriasis rosea
guttate psoraisis
fungal infection
most common presinting symptoms in pts
itchimg and burning sensation
Tx
NO tx is needed just symptomatic relieve using calamine lotion
not contagious chronic inflammatory skin disorder related to HCV pts
Lichen Planus
lichen planus etiologies 5
*1-idiopathic
2-genetic susceptibility
3-mercury
4-amaglam (dental filling )
5-drugs {bb-thiazide-anti-malarial-ACEi}
basal keratinocyte apoptosis is characteristic of
lichen planus.
if basal layer get damaged there is no stem cell to regenerate which cause thining in comparison to other DDx
T-lymphocytes in lichen planus target the
dermoepidermal *
junction
6P:
*
Planar
* Polygonal
* Papular
* Plaque
* Purple or Orange
pruritic
Wickham’s striae is
white streaky pattern on
the surface of
papules
*can be the sole manifistaion of this disease
complication
hair and nail loss ——
oral ulcers can devolops into ——
permenantly
squamous cell carcinoma
Tx
based on the definition adn presintaion
1-topical steroids
2-oral steroids {if sever :1-nail destruction 2-severe oral ulceration}
3-photochemotherapy{psoralen with uva with narrowband uvb }
4-ciclosporin and acitretin in refracrive cases
5-calcinurin and corticosteroids in Mucousmembrane lesions
