ACNE AND ROSACEA

Question 1

disorder of the pilosebaceous apparatus
characterized by comedones, papules, pustules, cysts and
scars

Answer 1

ACNE

Question 2

epdimiology of acne

Answer 2

It affects the sexes equally (12-14 y)
The peak age for severity in
_Females - 16–17y
Males 17–19 y
Associated with
Disfigurement/ Pain/ Loss of confidence/ Depression

Question 3

subacious gland secrete Sebum which consist
***its androgen dependant

Answer 3

mixture of:
Triglycerides/ Fatty acids/Cholesterol

Wax esters
Squalene

Question 4

acne 4 etiologies

Answer 4

1-bacterial colonization
2-poral occlusion keratinization
3-increased sebum production {ocp,puberty}
4-dermal inflammation

Question 5

Drug-induced acne
Dominated by papulopustules rather than
comedones

Answer 5

g corticosteroids, lithium,
anticonvulsants, barbiturates. androgenic
and anabolic steroids, gonadotrophins, oral
contraceptive

Question 6

Late onset qcne features

Answer 6

Mainly in womenOften limited to the chin
Nodular and cystic lesions predominate

Question 7

Bacterial infection of the hair follicle, appears in
patients in case of long time treatment with
doxycycline because it kills skin normal flora, high
risk of other gram negative to growth

Answer 7

Pyogenic folliculitis

Question 8

Any acne (even infantile)associated with
virilization (such as muscle bulk, body hair, and deep
voice) needs investigation to exclude an androgen- secreting tumor of the: adrenals, ovaries or testes &
to rule out congenital adrenal hyperplasia caused
by 21-hydroxylase deficiency.

Question 9

Concomitant eczema is a contraindication to their use

Answer 9

Tretinoin (Retin A), Adapalene (Differin), Tazarotene
(Tazorac

Question 10

Bactericidal effect on P.acnes
Adverse effects
 Irritation
 Bleaches clothing and hair
 Allergic contact dermatiti

Answer 10

benzoyel peroxide

Question 11

bacteriostatic for P. acnes
safe for pregnency and breast feeding

***used in darker skin patients as it may help to lighten
post-inflammatory hyperpigmentation

Answer 11

azelaic acid

Question 12

AB s in mild vs moderate to severs

Answer 12

mild :topical
Erythromycin, Clindamycin
moderate to severe|:systemic{Tetracyclin, Doxycyclin, Minocyclin}

Question 13

DOXYCYCLINE adverse effect

Answer 13

phototoxic skin
reactions
stained teeth and dental hypoplasia.
bone deformity