Papulosquamous diseases Flashcards
What is the gold standard for the diagnosis of tinea versicolor?
KOH (hydrogen peroxide) stain
What is the treatment for tinea versicolor?
Topical antifungal medications (selenium sulphide, fluconazole, ketoconazole).
What is tinea versicolor?
It is a fungal skin infection which interferes with the normal pigmentation of the skin.
What is the name of the organism that causes tinea versicolor?
Malassezia Pityrosporum
What are the most common drug eruptions?
- Urticarial drug eruption
- Morbilliform drug eruption
- Fixed drug eruption
- Lichenoid drug eruption
What are the causes of Morbilliform drug eruption?
- amoxicillin
- beta- lactam antibiotics
- sulphonamides
- allopurinol
What is type of reaction is morbilliform?
Type IV hypersensitivity reaction and it occurs 2 weeks after the drug is started.
What is the definition of Lichenoid drug eruption?
- Purple, pruritic, polygonal plaques. (4 P’s)
- May be seen in the nails but not in the oral mucosa
- It occurs 2 months after starting medication
What are the causes of Fixed drugs eruptions?
- paracetamol
- sulphonamides
- tetracycline antibiotics
What is the definition of fixed drug eruption?
Circular, erythematous rashes containing a blister usually pigmentation remains after healing.
What type of reaction is urticarial?
Type I hypersensitivity reaction
What is the definition of urticarial eruption?
Itchy, red wheals with angio - edema that can change form. Diagnoses is made with skin prick test and management with anti histamines.
What are the causes of urticarial eruption?
NSADs, beta - lactam antibiotics, ACE - I, opiates.
What are the causes of Lichenoid eruption?
- ACE- I
- BBs
- Thiazides
- antimalarials
- penicillamine
What is psoriasis?
Psoriasis is a non contagious, chronic, autoimmune inflammation characterized by erythematous SCALY plaques.
How is proriasis diagnosed?
Skin biopsy
Which drug is a precipitant of psoriasis?
Lithium
What is the most commonly prescribed topical corticosteroid?
Hydrocortizone
What is the treatment for pityriasis rosea?
Reassure and discharge.
What is the presentation of pityriasis rosea?
Herarld patch - a single large discoid erythematous patch, few days later a widespread rash appears across the trunk consisting of smaller, erythematous, scaly patches. These patches are distributed in a Christmas tree fashion.
How do you treat erythroderma?
Admit and ABCDE with IVF
What are the signs of lichen planus?
- Burning sensation when eating
- Irregular Purple plaques in the palmar aspect of the wrist lined with white lacy lines
Name the 6P’s of lichen planus.
- Pruritus
- Purple
- Polygonal
- Planar (flat)
- Plaques
- Papules
Where in the body can lichen planus present?
- Flexor compartment of the wrist
- Nails
- Oral mucosa
