Paper 3: PTSR, PHEBD Flashcards

1
Q

What are health determinants?

A

The many factors which shape and determine individual’s health
Complex interaction b/w individual characteristics, lifestyle and physical, social and economic environment

Economic hardship correlated w/ poor health
Inc. education strong and significant correlation improved health

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2
Q

Define health inequalities

A

Differences in health status or the distribution of health determinants b/w different popn. groups
Preventable and unjust differences experienced by certain groups
- low SES > chronic ill-health, die earlier cf high SES

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3
Q

Discuss inequalities in health determinants

A

SE, cultural, environmental

  • education, employment, living and working conditions
  • overcrowding, access, language and cultural barrier

Social and community networks
- social cohesion, isolation

Lifestyle

  • smoking, alcohol consumption
  • diet, physical activity
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4
Q

Social determinants of health

A
Poverty
Social exclusion 
Discrimination 
Poor housing
Unhealthy early childhood conditions
Low occupational status
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5
Q

Discuss social gradient in health and clustering of behaviours

A

Inequalities in health status are related to inequalities in social status
- life expectancy, chronic disease (CVD, DM, cancer)
Poorest have worst health
- health behaviours are socially patterned as social gradient within behaviours
- global phenomenon; affects everyone

Clustering

  • evidence of clustering of health behaviours and co-distribution
  • multiple risk factors are more common in some groups
  • more likely have poor health outcome
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6
Q

Discuss the life course approach of health inequalities

A

Biological, behavioural and social factors throughout life cumulatively impact health in adult hood

Environmental exposures may impact on development of chronic disease in later life by programming structure/function of organs/body systems

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7
Q

Factors affecting the life course approach

A

Accumulation of risk overtime
Chain risk model: sequence linked exposures raise risk
- 1 bad experience/exposure tends to lead to another
Critical periods: exposure during critical period of development
- potentially effect structure/function of organs/tissues/systems not modified in later life
Susceptibility
Time
Vulnerability

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8
Q

Discuss causes and importance of oral health inequalities

A

Causes
- main causes are social determinants (causes of causes)
- common risk factors for many chronic diseases (DM, CVD, mental illness, cancer)
— poverty, deprivation, employment, education
— diet, smoking, alcohol consumption
— injury
— hygiene

Importance
- quality of life; ability to eat, speak, socialise, sleep, smile
- psychological and social impact 
- costly to treat 
— Sweden 8% of health budget, UK 3.5%
- preventable
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9
Q

What is the common risk factor approach?

A

Method to tackle and prevent health inequalities by targeting shared risk factors of diseases
Non-communicable diseases (CVD, CRD, DM, cancer) biggest killers and have shared risk factors (tobacco, diet, inactivity, alcohol )
- prevent by tackling these risk factors; most effective

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10
Q

6 key areas for tackling health inequalities

A

Give every child best start in life
Enable everyone to max. capabilities and control their lives
Create fair employment and good work for all
Ensure healthy standard of living for all
Create and develop healthy and sustainable places and communities
Strengthen role and impact of ill health prevention

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11
Q

Define health promotion

A

Process of enabling individuals and communities to inc. control over health determinants thus improve their health

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12
Q

How has health promotion worked so far and how should this change?

A

Focused on downstream actions w/ limited effect

To be successful in changing behaviours need to change environments to ensure healthier choices are easier choices

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13
Q

5 action areas for health promotion outlined by Ottawa charter

A
  1. Building healthier public policies
  2. Creating supportive environments
  3. Strengthening community action
  4. Developing personal skills
  5. Reorientating health services towards prevention
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14
Q

5 approaches to health promotion

A
  1. Social change
    - recognises importance of SE and environmental factors in determining health
  2. Empowerment
    - support individuals in identifying concerns, priorities and developing skills to make change
  3. Preventive: clinicians deliver preventive advice/Tx
  4. Social change
    - encourage changing unhealthy behaviours to healthy ones
    - assumes if given knowledge will change behaviour
  5. Education
    - knowledge alone is insufficient to make change
    - need to develop skills and attitudes
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15
Q

Discuss up, mid and downstream approaches to health promotion

A

Upstream: legislative and fiscal policies

  • Ottawa: building healthy public policy + creating supportive environments
  • sugar tax, guidelines on sugar consumption
  • smoking ban in public places
  • free pre-school places to support parents and promote child development

Midstream: Training wider workforce on oral health
- Ottawa: strengthening community action + developing personal skills
- training community health champions
— deliver oral health advice, signpost community dental services
- healthy food policies in nurseries and schools

Downstream: 1ry care approaches

  • Ottawa: re-orientating health services towards prevention
  • implementation of prevention @ chair side using CRFA
  • DBOH: prevention toolkit
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16
Q

Discuss building healthier public policy and give examples

A

Mainly: legislation, fiscal measures, taxation organisational change

Subsidies for health related products
- staple foods to red. malnutrition and improve nutrition 
Tax and Tax Expenditures
- incl. excise and VAT; sugar, tobacco, alcohol 
- exemption from taxes
Reducing availability
- ban in schools
- limit no. on high street/area
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17
Q

Discuss creating supportive environments, give examples

A

Socio-ecological approach; safe, stimulating, satisfying, enjoyable living and working conditions

Healthy Cities

  • address inequality in health and urban poverty
  • needs of vulnerable groups
  • governance
  • social, economic, environmental health determinants

Congestion and Pollution: London congestion charge

Health Promoting Schools; Sugar Smart (Jamie Oliver)

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18
Q

Discuss Health Promoting Schools

A

Environment: physical, cultural, policies

  • safe, well-designed buildings and playgrounds prevent injury
  • no smoking, healthy foods served, packed lunch checks
  • safe water and good sanitation
  • protocol for bullying and violent behaviour and interpersonal conflict

Practice: curriculum, teaching, learning

  • curriculum change; health education part of every subject
  • training staff

Partnership: students, families, community, business

  • work w/ central/local health service providers
  • support school/community-based health promotion actives (breakfast club)
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19
Q

Discuss strengthening community action

A

Empowerment of communities to achieve social and political changes to improve their own health and control destinies

Mobilising Community Assets: knowledge, skills, physical and social resource
Community Capacity Building
- inc. resources and attributes through inc. knowledge, skills and competencies
Peer Support and Volunteers
- trained volunteers to enhance knowledge and skills to promote health
- Health Champions: provide and signpost health services
- Breastfeeding cafe
Partnerships: local health and social care services
Improving access: obvious resource centre to provide help and advice

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20
Q

Discuss developing personal skills

A

Provide individuals w/ health education and enhancing life skills to make choices conductive to health

Setting: school, home, work, community as individuals/communities/popn.
Empowering individual/community to take control over health through building confidence and self-esteem
Inc. knowledge, awareness, skills to promote +ve health change
Improving health status by supporting and giving skills to manage long term chronic conditions

Delivering Better Oral Health

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21
Q

Discuss reorientation of health services; how it can be achieved and an example

A

Health services must be sensitive to and respect cultural needs

How
- organisational change supports health promotion environment and capacity building of health service staff
- engagement and training of staff to practice evidence based medicine and promote health
- partnership and collaboration w/ communities and organisations
— priorities of community are priorities of health service

Primary Health Care Approach
Principles
- equity in access to care
- prevention and promotion 
- community participation 
- multi-sectorial approach
- appropriate technology

Goals

  • red. exclusion and social inequalities in health
  • organising health services around needs and expectations
  • integrating health into all sectors
  • pursuing collaborative models of policy dialogue
  • inc. stakeholder participation
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22
Q

Compare health, disease and illness

A

Health: complete state of physical, mental, social well-being not merely absence of disease

Disease: named pathological entities diagnosed by clinical signs and symptoms

Illness: how person feels when unwell and effect on their normal everyday life

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23
Q

Define oral health

A

WHO
Being free from: facial + mouth pain; oral + throat cancer; infection + sores; PD disease; tooth decay/loss; and other diseases that limit capacity to chew/smile/speak/bite and psychological well-being

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24
Q

Types of need and how these are measured

A

Normative

  • defined by professionals using agreed criteria
  • exam, BPE, X-ray, index of orthodontic Tx need

Felt

  • what individual perceived as important to them
  • history taking

Expressed

  • arise when felt need turned into action
  • dental attendance

Comparative

  • comparing needs on one individual/group to antiheroes
  • variations in attendance by gender, age, region
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25
Q

How do we assess impact on disease on QoL?

A

Oral Health Impact Profile (OHIP)

  • questionnaire
  • 7 domains
  • condensed format has 2Qs/domain
  • rate: hardly ever, occasionally, fairly often, very often
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26
Q

Domains of the OHIP-14

A

Functional Limitation

  • speak properly
  • sense of taste

Physical Pain

  • painful aching
  • pain whilst eating

Psychological Discomfort

  • worried
  • tense
  • self-conscious

Physical Disability

  • unable to eat satisfactory diet
  • interrupt meals

Physiological Disability

  • embarrassed by teeth
  • unable to relax

Social Disability

  • unable to do normal jobs
  • irritable w/ others

Handicap

  • feel life in general unsatisfactory
  • unable to function
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27
Q

Define special care dentistry

A

GDC 2008
Improvement of OH of individuals/groups in society who have physical, sensory, intellectual, medical, emotional or social impairment or disability or, more often, a combination of these

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28
Q

Define impairment, disability and handicap

A

Impairment: any loss or abnormality of psychological, physiological or anatomical structure or function

Disability: any restriction or lack of ability to perform activity in manner or within range considered normal

Handicap: when an individual w/ impairment can’t fulfil normal life role

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29
Q

Do all pt w/ disability req. SCD? What is the hierarchy for this?

A

No; most seen in GDP
If can’t be seen in 1ry care -> CDS -> hospital

Tier 1: seen by anyone w/ no specialist skills
Tier 2: additional complexity; hoist into dental chair
Tier 3: multi-disciplinary care; specialist or consultant

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30
Q

Main Tx modalities for SCD

A

LA
Sedation: IV or inhalation
GA: do need pre-medication/sedative?

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31
Q

Discuss Equality Act 2010 and impact for dental practice

A

Illegal to discriminate anyone w/ any form of disability

HCP must make reasonable adjustments to facilitate that attendance of individuals w/ disabilities to practice

  • hoists
  • ramp
  • handrails
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32
Q

4 key areas req. consideration when Tx special care pt

A
Access
- to dental service
- to chair 
- to mouth 
Valid consent 
Education: educate pt/carers on OH
Safety: pt, self, staff
- challenging behaviours
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33
Q

Discuss access to dental service for SCD

A

Awareness: do pt/carer know service exists
Support: req. transport getting to service?
Preparation: send pics to carers before, anything you can do to help?
Physical barriers: lifts, ramps
Info. provision
Extended services

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34
Q

Discuss how we can aid access to dental chair

A
Turntable: pt swivel into chair 
Hoist: attach pt to, move into chair
Diaco chair: wheelchair recliner
- more comfortable for pt
- better access
Bariatric chair: obese pt, support 180kg+
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35
Q

Discuss how to aid access to mouth in SCD

A

Physical support: hold pt if trained
Clinical holding
Positioning: often not ideal
Equipment design
Acclimatisation: good for Autism
- get pt outside, then into waiting room, then into surgery -> chair
Pharmacological management: sedation ease visit

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36
Q

What is valid consent?

A

Consent given freely
With all relevant information
Information is understood
Pt has capacity

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37
Q

Discuss the 5 key principles of the Mental Health Capacity Act 2005

A

Capacity presumed unless proven otherwise
Support pt decision making: communication aids
Respect right to unwise decision
Req. to act in pt best interest
Requisite to consider least restrictive option

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38
Q

How do we assess capacity?

A

2 stage test
Does pt have impairment/disturbance of mind/brain?
Is impairment sufficient that they lack capacity to make decision?

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39
Q

What are the criteria for someone to have capacity?

A

Must

  • understand info
  • retain info
  • weight up info
  • communication decision
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40
Q

What do we do if pt lacks capacity?

A

Tx in best interest: always get 2nd opinion, involve family

Consider
Advanced Directives
- had capacity + knew was going to lose
- dementia, Huntington’s
Lasting Power of Attorney 
- appoint someone to make decision on your behalf
- health, welfare or both 
Court Appointed Deputy
Independent Medical Capacity Advocate
- no family or friends
- involve to help make decision
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41
Q

What are possible communication differences/difficulties for SCD pt?

A

Anxiety: makes communication more difficult
Sensory: hearing, visual
Neurological deficit: following stroke
- Brocker’s aphasia: understand but lack vocabulary
- Verner’s: articulate but don’t understand
Muscular deficit
- articulation and phonation
- Multiple sclerosis: understand, voice muscles don’t work

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42
Q

Define challenging behaviours

A

Culturally abnormal behaviour of such intensity/freq./duration that physical safety of person or others is placed in serious jeopardy or seriously limits/denies access to community facilities

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43
Q

Define GA

A

Drug induced state of reversible, controlled unconsciousness during which pt not rousable

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44
Q

Indications for GA

A

General

  • anxious pt w/ OSA
  • multiple XLA/8s
  • failed sedation
  • maxfax

SC
- aspiration risk: instruments, saliva
— cerebral palsy: infection + pneumonia post surgery
- cognitive impairment w/ challenging behaviours
- multi-disciplinary care

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45
Q

Contraindications for GA

A

Allergy to drug
Social: no escort for sedation
Advanced cardio-respiratory disease

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46
Q

Factors important in medical and social history for GA

A

M

  • CV or respiratory disease
  • habitus
  • veins

S: does pt have support from friends/family/carers

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47
Q

Importance of previous GA and airway history for new GA

A

GA

  • suxamethonium apnoea (lack enzyme to metabolise)
  • malignant hyperthermia
  • adverse reaction/allergy

Airway

  • failed intubation
  • unstable cervical spine
  • specific syndrome: Treacher Collins
  • limited opening
  • acromegaly
  • ankylosing spondylitis
  • rheumatoid arthritis
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48
Q

Medical and dental considerations when considering pt for GA

A

M

  • liaise w/ anaesthetist, gastroenterologist, ENT
  • investigations: blood tests, ECG, echo

D
- CONSENT: pt best interest
- realistic Tx planning: not having multiple GA
- reasonable adjustments (facilitating access to care)
— multiple specialities working in 1 appt

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49
Q

Discuss aspects of intra-operative care during GA

A
Maintenance: sevoflurance, propofol
Analgesia: fentanyl, local analgesia 
Anti-emetic: cyclizine, ondansetron
Fluids: saline
Pt warming (prevent hypothermia)
Venous thrombosis prophylaxis: enoxaparin
- stocking, calf compressors 
Steroids
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50
Q

In the recovery of GA what is special consideration for SCD pt?

A

Reasonable adjustment as soon as ready let them go as may be traumatising keeping them longer than req.

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51
Q

Risks + side effects of GA

A
Nausea, vomiting 
Sore throat/nose
Shivering
Trauma to dentition 
- tooth dislodged by oropharyngeal scope 
- check before + after 
Corneal abrasions
Chest infection 
Delirium/cognitive dysfunction 
Anaphylaxis: 1:15000
Awareness: 1:15000
Nerve damage 
Death: 1:100000
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52
Q

Important blood tests to check for medically compromised pt

A
Hb: 13-17g/dL
- GA/sedation: <8x10^9/L
Neutrophil: 2-7x10^9/L
- low = infection susceptibility 
Platelets: 150-400x10^9/L
- low = bleeding
- infiltration: 20
- IDNB: 30
- XLA: 50
- surgical: 75
INR: 0.9-1.1
- higher = bleeding
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53
Q

Discuss the implications of weight for Tx SCD pt

A
Overweight
- airway management + handling issues
- bariatric chair?
- co-morbidities
— CVD
— DM
— fatty liver disease

Underweight

  • anaemia
  • bradycardia, hypotension
  • psychiatric: diabulimia
  • osteoporosis
  • reflux
  • dental implications: erosion
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54
Q

Discuss respiratory disease considerations for SCD

A
Asthma
- how well controlled?
- poorly: extra care
— have been hospitalised?
— how many steps before difficulty breathing?
- Rx condition on Tx day 
- bring inhalers w/

COPD: emphysema, bronchitis

  • most undiagnosed airway condition
  • productive cough + U airway sensitivity
  • low baseline O2 saturation; esp. smokers
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55
Q

Discuss medications used to Tx COPD

A

Pt using medication further down indicates poorly controlled at some point

Salbutamol (short acting B2 agonist)
Beclometasone (glucocorticoid)
Salmeterol (long acting B2 agonist)
Theophylline

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56
Q

Compare T1 and T2 DM

A

T1: IDDM

  • younger popn.
  • lack insulin thus pt on insulin
  • more difficult to control

T2: IIDM

  • older
  • Afro-Caribbean
  • insulin resistance (rarely on insulin)
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57
Q

Common complications of poorly controlled DM

A

Eyes: retinopathy, leading cause of blindness
Heart: atherosclerosis -> TIA, MI, angina
Kidney: nephropathy -> chronic kidney disease
Feet: infections, paraesthesia (polyneuropathy)

58
Q

Discuss medications used for Tx of DM

A

T1: insulin
T2
- metformin
- + sulphonyurea (gliclazide) or DPP-4 inhibitor (sitagliptin)
- + thiazolidinediones: pioglitazone
- + insulin = poorly controlled @ some point

59
Q

What is glycated Hb? How is it used?

A

Hb1Ac: measure of glycosylated Hb in blood over 3/12
Low = well controlled

<42mmol/mol = normal
42-47: prediabetes
>48: diabetes

60
Q

Discuss cardiac risk groups and implication for AB cover

A

Groups

  • cardiomyopathies
  • valve disease w/ stenosis/regurgitation
  • valve replacement
  • congenital HD
  • previous Hx IE

Cover

  • NICE: no one needs cover
  • previous IE: cultures isolated? Oral bacteria?
  • consult cardiologist
61
Q

Discuss anticoagulant medications and implications for dental Tx

A

Warfarin

  • VitK dependent CFs: 2, 7, 9, 10
  • INR<4 for Tx/XLA

LMWH: enoxaparin, dalteparin, tinzaparin

  • CF2, 10
  • kidney pt on dialysis
NOACs
- dabigatran: thrombin inhibitor 
— skip morning dose
- apixaban: CF10A inhibitor 
— skip morning dose
- rivaroxaban: CF10A
— 1/day
— delay morning dose until 4h post-haemostasis
62
Q

Signs of pt w/ bleeding disorder

A
Bleeding gums
Previous bleeding post-op
Easy bruising 
Haemaethrosis: bleeding into joints 
Petechiae: skin bleeding
Heavy periods
63
Q

Signs of renal failure/disease

A
Lemon tinge to skin 
Halitosis 
Peritonitis
Hypertension
Anaemia: EPO (hormone) prod. RBC
Bone pain: VitD, Ca2+ regulation 
Proteinurea 
Itchy skin
64
Q

Dental Tx implication for renal pt

A

Access
- if on haemodialysis must see day after dialysis
- given heparin + will be lethargic
Risk assess chance of bleeding

65
Q

Signs of liver disease

A
Encephalopathy 
Bleeding: CD 2/7/9/10
Jaundice: bilirubin 
Dry mouth/excessive thirst
Gynecomastia
Infections: dec. macrophages
Ascites
Telangiectasia 
Dupuytren’s Contracture
Hepatocellular carcinoma 
Resting tremor
66
Q

Implications of liver disease on dental Tx

A

Poor OH: Dupuytren’s contracture, resting tenor, encephalopathy
Caries: above + dry mouth
Infections
Bleeding

Do clotting screen pre-Tx

67
Q

Common immunosuppressant drugs

A
Tacrolimus: interaction w/ erythromycin 
Cyclosporin: gingival swelling 
Mycophenolate mofetil
Prednisolone: how long?
Monoclonal Abs: fewer side effects
68
Q

Dental impact of pt on immunosuppressants/transplant

A
No Tx for 1st 3/12: rejection likely
Prevention is key 
Review regularly 
Infections
- Candida 
- HSV
- oral hairy leukoplakia 
- ulcers

No AB cover
Steroid cover if req.

69
Q

What is graft v host disease? Dental relevance?

A

Immune condition where graft immune cells attack host tissue

Dental: most likely to be 1st clinician to see

  • ulcers
  • hyperkeratotic patches
  • mucosal atrophy
  • lichenoid changes
  • erythema
70
Q

Pre-Tx checks for HIV pt

A
How long have had HIV?
What medications on?
- atripla 
- combivir
- kaletra
Bloods
- CD4 >200: immune response 
- VL <40: infectivity
- platelets: inc. likelihood thrombocytopenia (low)
71
Q

Discuss psychiatric disorders and dental relevance

A
Under-diagnosed + inc. (esp. young)
May not disclose 
Clues: MH + drugs
- typical: clozapine, haloperidol
- atypical
— olanzaline
— risperidone
— amisulpride
— ariprazole
- side effects: pancytopenia (red. WBC, WBC, platelets)

Dental

  • anxiety
  • eating disorder: erosion
  • dementia
  • bleeding, infections
72
Q

Dental management for thalassaemia and sickle cell disease pt

A
Inhalation sedation generally safe
- care w/ GA
Avoid
- hypoxia: O2 for 5 mins pre-appt
- hypothermia: give blanket 
- hypovolaemia: ensure drink plenty water 
Red. dental related stress
Tx infections aggressively
- post-op ABs for all surgeries 
Avoid high dose aspirin
73
Q

General signs and symptoms of oncology pt

A
Malaise
Fever
Lymphadenopathy 
Bleeding gums
Weight loss
Haematurea
Infections
VTE/PE
74
Q

Importance of chemo and radiotherapy for oncology pt and dental relevance

A

Tx modality

Chemotherapy
- leads to pancytopenia
— low neutrophils -> infections
— low platelets -> bleeding
— low RBC -> anaemia 

Radiotherapy

  • osteoradionecrosis
  • must know RT fields + sites
  • dose?
75
Q

Dental impact of chemo-radiotherapy

A
Mucositis: inflammation and ulceration of mucosa
Loss of taste
Dry mouth: immediate and long term
Caries
Trismus
76
Q

What is osteonecrosis? Aetiology and pathophysiology

A

Exposed bone for >2/12 (in irradiated site for ORN)
Aetiology
- trauma: XLA, biopsy, ill fitting denture
- spontaneous: mylohyoid ridge
Pathophysiology
- endarteritis (inflammation of artery)
— dec. vascularity, abnormal fibroblast activity, red. osteocytes
— = red. bone turnover

77
Q

Signs of ONJ

A
Erythema
Swelling
Discharge 
Pain
Exposed bone
Oro-cutaenous fistula
Pathological #
78
Q

Issues w/ caring for older pt

A
MH
- safety
- ability to accept Tx
- prioritisation 
Attitude towards Tx
79
Q

Dental and mucosal changes seen w/ ageing

A

Dental

  • calcification
  • inc. mineralisation
  • wear

Mucosa

  • red. mucosal thickness
  • loss of vascularity
  • red. cell turnover
80
Q

Pathological changes seen in OH w/ ageing

A

Red. saliva flow: normal physiological + poly-pharmacy

Alveolar bone restoration

  • following XLA/loss
  • physiologically accelerated in some pt
  • WHO: severely red. ridge = disability

Loss of muscle tone + strength

  • red. bite force
  • mobility issues
  • access: chair transfer
81
Q

Discuss chronic dental disease and older pt ability to self care impact on OH

A

Chronic disease

  • progressive PDL loss (mobility, loss)
  • extensive, complex restorations
Self Care
- frailty: stroke, Parkinson’s, arthritis
— unable to brush 
- dementia: completely dependent
- depression, social isolation
82
Q

Link b/w OH and medical health esp. in older pt

A

Aspiration pneumonia

  • poor OH + PD disease contribute
  • plaque acts as bacterial reservoir
  • hospital/care home pt have poor OH + 48% of infections care home pt

DM

  • well established risk for PD disease
  • PD inflammation associated w/ impaired glucose tolerance

CVD + Stroke

  • some evidence of PD disease link
  • PD disease may be risk factor for CVD
83
Q

What habits do older pt tend to have which impact oral health?

A

Sugar: inc. amount + freq.
OH: less brushing 2x daily

84
Q

3 main methods of prevention for older pt

A

Fluoride
Plaque control/OH
Diet modification

85
Q

Discuss provision of F for older pt

A
High conc. toothpaste (Duraphat): 2800/5000ppm
Use weekly rinse (0.2%) daily 
- only if will spit 
H2O fluoridation 
FV: every 3/12, 22600ppm
86
Q

Issues w/ + methods of plaque control for older pt

A

Dexterity problems

  • modified brush: putty to shape handle
  • electric brush
  • chlorhexidine: adjunct

Dependency: training of carers (effect short lived likely due to turnover of carers)

HCP: regular hygiene appt

Interdental aids

87
Q

Signs of learning disability

A

Speech impairment

  • verbal limitation
  • use alternatives: sign language, written

Poor OH
- severe LD hate having things in mouth

IQ

  • profound <20
  • severe <35
  • mod 35-49
  • mild 50-69

Mortality 28x higher
LE 4x lower

88
Q

Types, Dx and Tx for Down’s syndrome

A

Types

  • trisomy 21 93%
  • translocation trisomy 21
  • mosaicism

Dx: USS; width of head
Tx: SALT, physio

89
Q

Facial features of Down’s syndrome

A

Mongoloid appearance
Brachycephaly
Mid-face hyperplasia

90
Q

Denture features of Down’s syndrome

A
Microdontia
Hypodontia
Macroglossia
Malocclusion 
Fissured tongue 
PD disease + caries
91
Q

Signs of Down’s syndrome

A
Learning difficulty: 100% pt
Dementia: 55%
Leukaemia: 10-20x higher 
Brushfield’s spots/cataracts
Clinodactyly
Simean crease 
Short neck
Atlanto-axial instability 
Joint flexibility 
ASD/VSD: 53%
Hypothyroidism: 27% -> weight gain + obesity 
Short stature
Hearing impairment
92
Q

Discuss autism

A

Aetiology unknown: possibly chromosome 15
Spectrum of disorders

Triad of impairments 
- social communication 
- social imagination 
- social isolation 
Possibly accompanied by challenging behaviour 
Desire for sameness/routine
93
Q

Signs of autism

A
Hate eye contact
Learning disability 
Challenging behaviour: possible GA
Self harm
Fixation w/ numbers 
Repetitive movements 
Mood disorder
Dislike physical stimuli
94
Q

Aetiology of cerebral palsy

A

Prenatal

  • maternal infection: acute (rubella), chronic (syphilis, herpes)
  • maternal dysfunction: DM, hypertension
  • drugs: alcohol, recreational

Neonatal

  • prematurity
  • difficult/prolonged labour
  • hypoxia (most common)
  • birth injury

Postnatal

  • trauma, brain tumour
  • infection: meningitis, encephalitis
  • toxins: Pb, hydrocarbons
95
Q

Types of cerebral palsy

A

Spastic (50-60%): cortical motor area

  • exaggerated movements, inc. muscle tone, hyperreflexia
  • inc. spasticity, contracture

Athetoid (20-35%): basal ganglia
- writhing, wormlike movements

Ataxic (7-15%): cerebellum
- lack coordination (hand to eye), balance problems (gait)

96
Q

Signs of cerebral palsy

A

Epilepsy (30%)
Learning disability
Sensory impairment: hearing, visual, speech
Uncontrolled movements

97
Q

Oral features of cerebral palsy

A
Malocclusion: class 2 div 1 (lack muscle tone)
High palatal vaults 
Tongue thrust, mouth breathing 
Drooling
- Botox injection + anticholinergic patches -> xerostomia 
Xerostomia: caries 
Narrow arch
Enamel hypoplasia
Bruxism 

PD disease 3x higher

98
Q

What is Parkinson’s disease?

A

Motor neurone disease caused by degeneration of dopaminergic cells in substantia nigra

99
Q

Aetiology of Parkinson’s

A

Multifactorial

Genetics
Idiopathic
Drug: neuroleptics (reserpine, phenothiazines)
Post-viral encephalitis, other degenerative
Diffuse brain disease causing generalised cerebral damage: Alzheimer’s

100
Q

Tx of Parkinson’s

A

Physio +

Levodopa
- dopamine precursor; replenish dopamine
Adverse: hallucinations, confusion, dystonia, xerostomia
Use w/ dopa decarboxylase inhibitor to allow lower dose w/ inc. dopamine conc. centrally

101
Q

Signs of Parkinson’s

A

Mask-like face
Facial rigidity
Red. spontaneous blinking
Speech slurring

Bradykinesia: slow movements + hesitant initiation
Dyskinesia: involuntary movement
Pill-rolling Tremor

Limb rigidity
Shuffling gait

102
Q

Dental implications of Parkinson’s

A

Accommodation: on + off days/times
Give pt time for communication

Disease: xerostomia, dietary supplements (high sugar), red. dexterity

103
Q

What is multiple sclerosis? Aetiology?

A

Neurodegenerative disease caused by damage to myelin sheath of brain + spinal cord

Aetiology: unknown

104
Q

Types of multiple sclerosis

A

Benign (20%): few mild attacks then complete recovery
Relapsing/Remitting (25%): symptomatic + asymptomatic periods -> 15y
2ry progressive (40%): begin as R/R, symptoms more freq. + worse
1ry progressive (15%): early onset, worsen over T w/ period of remission

105
Q

Signs of multiple sclerosis

A

Fatigue
Sensory impairment: visual, verbal (articulation)
Breathing: shortness of breath, coughing, difficulty
Uncontrolled movements + spasticity

106
Q

Oral features of multiple sclerosis

A

Xerostomia

Caries

107
Q

Tx of multiple sclerosis

A

Disease modifying drugs: red. no. relapses + slow progression
No Tx for 1ry progressive
Physio + steroids to speed recovery b/w attacks

Drugs: anti-incontinence, cannabis (pain)

108
Q

Dental implications and management for pt w/ multiple sclerosis

A

Implications

  • cannabis -> caries (munchies)
  • dry mouth
  • trigeminal neuralgia: don’t know cause of pain as communication difficult

Tx

  • consent: pt understands!! Find way to communicate
  • aspiration risk later stages: RD
  • prevention
109
Q

Aetiology of Huntington’s disease

A

Neurodegenerative

Autosomal dominant
Faulty gene on chromosome 4
- causes cerebral atrophy + mutated huntingtin protein

110
Q

Signs of Huntington’s disease

A
Speech impairment 
Uncoordinated, jerky movements
Lack of coordination
Unsteady fair
Suicide risk
Dementia 
Mood + cognition changes 
swallowing difficulty p
111
Q

What is a stroke? Risk factors

A
Sudden neurological deficit, vascular in origin lasting >24h
Risk factors 
- DM, obesity
- smoking 
- hyperlipidaemia 
- heart failure
- carotid artery stenosis
- ischaemic heart disease
- Afib
112
Q

Differentiate b/w 2 types of stroke

A

Haemorrhagic: weak/diseased blood vessel ruptures, blood leaks into brain

Ischaemic: blood clot prevents blood flowing to brain

113
Q

Tx of stroke

A

Initial

  • thrombolysis: only ischaemic
  • surgery: stent, hemicraniectomy

Prevention: anticoagulation (ischaemic)

Rehab: SALT, OT, physio

114
Q

Complications of stroke

A

Paralysis, muscle weakness
Incontinence
Social isolation
Dementia

Dysphasia
Agnosia: inability to process sensory info
Dyspraxia: poor coordination
Dysarthria: poor articulation (slurred)
Aphasia (difficulty understanding)/Dysphasia (difficulty generating)
Loss of language

115
Q

Dental features and implications for Tx for stroke pt

A

Features

  • xerostomia
  • caries: B/root
  • facial paralysis
  • PD disease

Tx
- access: wheelchair recliner, hoist
— domiciliary care, pt transport
— poor attendance
- position + handling: leaning to 1 side; cushion/support
- aspiration risk
- OH: toothbrush/denture modifications aid cleaning
- dentures: help put in, adjust to accommodate loss of muscle

116
Q

What is dementia? Aetiology

A

Progressive and irreversible impairment of cognitive function
Alzheimer’s most common

Aetiology

  • unknown
  • no. of possible causes, nothing conclusive
117
Q

Signs of dementia

A
Memory loss
- initially short term, then long term
Orientation: where they are, movements
Understanding: language, confusion 
Language: lack
Personality + behavioural changes
118
Q

Management of dementia

A

No cure, maintain QoL
Drugs
- slow progression
- manage associated behaviour/depression

119
Q

Impact of dementia on dental care + Tx

A

Care

  • cooperation: confusion, aggression, forgetfulness
  • OH: dependent on others, train carers
  • consent: check continually as progresses -> best interests
Tx
Early
- major Tx
- clear + simple communication 
- LA + TLC
- clinical holding 
Moderate
- Least traumatic, similar surroundings 
- IVS/GA if medically stable + cooperative 
— slow, careful administration 
Advanced
- as above +
— palliative care
— pain management
120
Q

Aetiology of anxiety + possible reasons for dental anxiety

A

Aetiology

  • last threats
  • lack of control
  • previous learning
  • classical conditioning
  • cultural: films/torture

Dental
- hierarchy of dental Tx related-anxiety: XLA > LA > filling
- anticipation
- triggers
— visual: instruments
— auditory: sound of drill
— olfactory: smell of practice/medicaments

121
Q

Behavioural and physiological signs of anxiety

A

Behavioural

  • verbal abuse
  • excessive talking (delay)
  • cancelling/late/missing appts

Physiological

  • pallor, sweating
  • dry mouth
  • knotted stomach
  • flushed face
  • extreme muscle tension
  • fainting, hyperventilation
  • inc. HR + BP
122
Q

Discuss the modified dental anxiety scale

A

Measurement of severity of anxiety

5Qs, 5 responses
Score = sum of responses
- 19+ = high anxiety
Quick, easy

123
Q

Management options for pt w/ anxiety

A

Behaviour techniques + psychological methods

Pharmacological

  • GA
  • conscious sedation: IVS, IHS, oral
124
Q

Discuss midazolam: t1/2, pharmacodynamics

A
Distribution t1/2: 6-15min
Elimination t1/2: 1-3h
- ~8-12h before cleared 
Relatively inactive metabolites 
High therapeutic index: wide margin of safety 

Pharmacodynamics

  • anxiolysis
  • muscle relaxant
  • anterograde amnesia
  • sedation
125
Q

Midazolam mechanism of action

A

Benzodiazepine receptor agonist

BZD R associated w/ GABAA R
Midazolam inc. effect GABA on GABAA R causing influx of Cl- resulting in cell inhibition

126
Q

Discuss flumazenil

A

Competitive antagonist @ BZD R (prevent midazolam binding)
Used as BZD antidote
- reverses all effects of midazolam except anterograde amnesia
Elimination t1/2: 1-1.5h (shorter)
- during this re-sedation won’t occur

127
Q

Discuss anterograde amnesia effect of midazolam

A

Benefit: red. pt’s memory of Tx
Unhelpful
- difficult to wean pt away from sedation Tx
-misinterpreted by pt: ‘put to sleep’
Most profound effect
- immediately after induction
- variable loss of short term memory: hrs-next day

128
Q

Discuss muscle relaxant effect of midazolam

A

Generally unhelpful except mouth opening

Difficulty
- standing
- walking
- maintaining balance
Airway obstruction in over-sedated + pt w/ snoring/OSA
- obliteration of oropharynx by tongue falling back
Loss of protected gag reflex

Helpful for pt w/ gag reflex

129
Q

Discuss respiratory depression effect of midazolam

A

Usually mild

Mechanisms
- respiratory muscles relax causing dose-related red. rate + depth of breathing
- red. sensitivity of central CO2, O2 chemoreceptors
— red. ability respiratory centre to inc. respiratory drive in presence of high CO2/low O2

Monitoring w/ pulse oximeter mandatory

130
Q

CV effects of midazolam

A

Few significant effects

Dec.

  • mean arterial pressure
  • cardiac output
  • stroke vol.
  • systemic vascular resistance

Present as small fall in arterial BP

131
Q

Indications for IHS

A
Children 
Mild/mod. anxiety 
Needle phobia 
Other sedation C/I
Medical condition 
Long cases (no sedation window)
132
Q

Properties of NOx + mechanism

A

Odourless, colourless, nonirritant gas
Low blood solubility
Easy titration
Rapid recovery

Mechanism: unknown
- diffuses into blood, conc. in tissues w/ high blood flow

133
Q

Systemic effects of NOx

A

CVS: vasodilation
Resp.: red. rate + depth
GI/liver/kidney: N/A
Haematopoietic: bone marrow suppression

134
Q

Normal distribution of pts’ response to sedation

A

Hyporesponder

  • effective @ max dose
  • abuse of CNS-mediated drug

Hyperresponder

  • effect @ low doses
  • red. CNS mediation (older)

Paradoxical effects: young, old

135
Q

Compare titration regime for health adult, elderly and overweight pt

A

Healthy adult

  • 2mg/30s
  • pause: 60-90s
  • further: 1mg every 30s

Elderly

  • 1mg/30s
  • pause 120-240s
  • further: 0.5mg every 30s

Overweight

  • 2mg/30s
  • pause 60-90s
  • further: 0.5mg every 30s
136
Q

Req. for level of conscious sedation

A

Level so pt

  • remains conscious
  • retains protective reflexes
  • able to understand + respond to verbal command
137
Q

Describe sedated pt and clinical signs

A

Sedated pt

  • relaxed
  • cooperative
  • dec. awareness of surroundings
  • demonstrate diminished response to stimuli

Clinical

  • resp: normal 12-20/min
  • eye: follow finger (slower)
  • protective reflexes intact
  • eyelid reflex: intact (conscious), absent (over-sedated)
138
Q

Signs of over sedation

A

Unconsciousness
Irregularly respiratory pattern
Hyperactive reflex

139
Q

Discuss management of over-sedation

A

Small amount
- uncooperative (refuse to open mouth)
— delay Tx start
- waiting few mins usually resolves

Gross

  • profound respiratory depression or apnoea
  • immediately stop Tx, maintain airway, ventilate if req.
  • reverse sedation
140
Q

Discuss titration regime for flumazenil reversal of sedation

A

Initial dose: 0.2mg/15s
Further: 0.1mg every 60s; max 1mg
Usually 0.3-0.6mg