Pancreatic Function Flashcards
What are the two morphologically and functionally different tissues within the pancreas?
Endocrine and exocrine tissues.
Digestive fluid within the pancreas contains a pancreatic fluid with an alkaline pH of 8.3. What causes the alkalinity of this fluid? What is its purpose?
High concentration of sodium bicarbonate; helps neutralize the hydrochloric acid within the gastric fluid.
Pancreatic fluid has about the same concentrations of which two electrolytes?
Potassium and sodium.
The digestive enzymes, or their proenzymes secreted by the pancreas, are capable of digesting which major classes of food substances?
Proteins, carbohydrates, and fats.
Pancreatic fluid contains which proteolytic enzymes?
Trypsin, chymotrypsin, elastase, collagenase, and leucine aminopeptidase.
Pancreatic fluid contains which lipid-digestive enzymes?
Lipase and lecithinase.
Pancreatic fluid contains which carbohydrate-splitting enzyme?
Amylase.
What is the purpose of nucleases (ribonuclease) in pancreatic fluid?
To separate the nitrogen-containing bases from their sugar-phosphate strands.
Pancreatic action is under hormonal control of which two hormones?
Secretin and cholecystokinin (CKK).
What is the function of secretin?
The production of bicarbonate-rich (alkaline) pancreatic fluid, which protects the lining of the intestine from damage.
What is the function of cholecystokinin (CCK)?
In the presence of fats or amino acids, it can cause cells to stimulate pancreas, intestinal motility, gallbladder, and stomach.
What enzyme in saliva is responsible for the breakdown of carbohydrates?
Amylase.
What enzyme in saliva is responsible for the breakdown of lipids?
Lipase.
What is the primary purpose of parietal cells?
Acts as an intrinsic factor for B12 absorption and HCl.
Chief cells within the stomach and intestine are responsible for which proenzyme? What is its purpose?
Pepsinogen; breakdown of proteins.
