Pancreatic Disease Flashcards

1
Q

Describe the exocrine pancreas and it’s function:

A

Exocrine panc = 85% of total panc.

Secretes digestive enzymes into duodenum

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2
Q

What are some causes of pancreatitis?

A

Hypoxia
Mini Schnauzers with fat metabolism issues
Trauma
Infection

most times we do not know

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3
Q

T/F: Pancreatitis is believed to be the fault of pancreatic auto-digestion due to the over-activation of digestive enzymes

A

True

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4
Q

Acute vs Chronic pancreatitis:

A

Acute = need to be aggressive with tx, fully reversible

Chronic = irreversible, more vague signs

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5
Q

Common CS of pancreatitis:

A

V+
D+
Anorexia
Abdominal pain

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6
Q

How can we diagnose pancreatitis? What enzymes do we look @?

A

Bloodwork: hyperglycemia, hypoK, hypoCa

Enzymes: TLI/PLI

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7
Q

Describe TLI enzyme:

A
  • pancreas-specific
  • decreases in EPI
  • better to use it in acute vs chronic pancreatitis
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8
Q

Which enzyme may be better in chronic pancreatitis?

A

PLI

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9
Q

How can we treat pancreatitis?

What kind of food can we give?

A
Fluids
Antacids/antiemetics
Abx
Antioxidants 
Analgesia

Food = low fat in dogs

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10
Q

Prognosis for acute vs chronic pancreatitis:

A

Acute can be life-threatening

Chronic may have fair prognosis

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11
Q

What is triaditis?

A

Pancreatic inflammation+hepatitis+GIT inflammation

most times we see 2/3

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12
Q

Which breeds commonly get EPI?

A

Rough collies

GSD

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13
Q

What is EPI?

A

Maldigestive disorder due to pancreatic acinar atrophy

**remember the acini secrete digestive enzymes normally*

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14
Q

T/F: Chronic pancreatitis can lead to EPI:

A

True

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15
Q

CS of EPI:

A

Weight loss - can’t digest
Poor coat - B12 deficient
D+/Steatorrhea - greasy

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16
Q

How do we diagnose EPI?

A

Fecal

Bloodwork - assess TLI [will be low]

17
Q

Treatment for EPI:

A

Pancreatic enzyme supplementation
B12 supplementation
Diet
Abx

18
Q

Describe the pancreatic enzyme supplementation tx method:

A
  • we usually use power but this can cause oral mucosal irritation
  • can also use fresh pancreas from butcher but this is raw = salmonella
19
Q

Describe EPI diet:

A

Highly digestible [because they can’t digest!!]

AVOID high fat/fiber

20
Q

What is a major paraneoplastic syndrome of primary pancreatic neoplasias?

A

Alopecia

Steatitis = very painful fat inflammation

21
Q

Is mass removal done in pancreatic neoplasias? Is chemo?

A

We can try to remove the mass if it compressing other organs
Chemo/radiation is not useful