pancreas quiz 5

Question 1

What is the #1 cause of acute pancreatitis?

Answer 1

gallstones (more common in women)

Question 2

1 cause of chronic pancreatitis?

Answer 2

alcohol (this is more common in men)

Question 3

labs for pancreatitis?

Answer 3

serum amylase and lipase 3 times higher than normal

Question 4

chronic pancreatitis

Answer 4

shrinks, fibrotic, fat necrosis

Question 5

what is most common type of pancreatic cancer?

Answer 5

pancreatic adenocarcinoma

Question 6

where does pancreatic adenocarcinoma arise from?

Answer 6

exocrine portion of pancreas
99% from pancreatic ducts
1% from acinar cells

Question 7

what is prognosis for pancreatic cancer?

Answer 7

bad

4th most common cause of death from cancer worldwide

Question 8

sequelae of acute/chronic pancreatitis?

Answer 8

pancreatic pseudocyst
infected necrosis
pancreatic abscess (infected pseudocyst)

Question 9

pancreatic pseudocyst

Answer 9

cyst in pancreas with fibrous capsule

• high concentration of pancreatic enzymes
• no epithelial lining on inside (no true epithelium)

Question 10

pancreatic abscess

Answer 10

infected pseudocyst or fibrous wall forms around fluid collections

• could rupture
• infected with gut bacteria

Question 11

where would be the worst area of pancreas to have a problem?

Answer 11

posterior inferior

Question 12

What area are you more likely to diagnose early with pancreas?

Answer 12

problems in head of pancreas because it causes earlier jaundice

Question 13

what can chronic pancreatitis lead to?

Answer 13

diabetes

increases risk for pancreatic cancer

Question 14

what bugs does pancreatic abscess contain?

Answer 14

e. coli, klebsiella, pneumoniae, etc

Question 15

malignant tumors of exocrine pancreas?

Answer 15

pancreatic adenocarcinoma

mucinous cystadenocarcinoma

Question 16

pseudopapillary tumors

Answer 16

benign
solid
well-demarcated
hemmorhagic on cut sections
associated mostly with women

Question 17

hist of pseudopapillary tumors

Answer 17

sheets of cells
uniform nuclei
cystic areas between tumor cells = “pseudo papillae”
PAS positive eosinophilic cytoplasmic inclusions

Question 18

most frequent cystic tumors of pancreas and 50% of all cystic tumors

Answer 18

mucinous cystadenoma

Question 19

second most common cystic tumor of pancreas. Honeycombed appearance. Benign

Answer 19

Serous cystadenoma

Question 20

What syndrome is are serous cyst adenomas associated with?

Answer 20

von-hippel-lindau syndrome: genetic condition with cysts in pancreas, liver, kidney and hemangiblastomas in cerebellum, spinal cord, etc

Question 21

what is pancreatic adenocarcinoma associated with?

Answer 21

Trousseau’s syndrome of hyper coagulability

Question 22

Does pancreatic adenocarcinoma affect endocrine system?

Answer 22

It is in ducts so it doesn’t effect endocrine function.