Pancreas Histology Flashcards

1
Q

Where are the adrenal glands located?

A

Perirenal fat at superior poles of kidneys

retroperitoneal

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2
Q

What is the function of the adrenal glands?

A

Secrete steroids and catecholamines

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3
Q

Innervation to the adrenal glands?

A

Sympathetic - preganglionic extend all the way to medullary chromaffin cells

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4
Q

Medullary chromaffin cell germ line?

A

Neural crest cells

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5
Q

Adrenal cortex germ line?

A

Mesoderm

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6
Q

What part of the adrenal gland secretes steroids?

A

Cortex

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7
Q

What part of the adrenal gland secretes catecholamines?

A

Medulla

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8
Q

The inner part of the adrenal gland is the _____

A

medulla

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9
Q

What are the three zones of the adrenal cortex?

A

Zona Glomerulosa
Zona fasciculata
Zona reticularis

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10
Q

This zone of cortex sits adjacent to the capsule (the most superficial part)

A

Zona glomerulosa

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11
Q

This zone of cortex sits closest to the medulla

A

Zona reticularis

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12
Q

What will the cells of the zona glomerulosa look like?

A

Round, basophilic nuclei
Eosinophilic cytoplasm
Abundant smooth ER
Sparse lipids

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13
Q

What does the zona glomerulosa produce?

A

mineralocorticoids :

Aldosterone and deoxycorticosterone

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14
Q

Spongiocytes are found here

A

Zona fasciculata

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15
Q

This zone makes up 80% of the cortex

A

Zona fasciculata

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16
Q

What do spongiocytes look like?

A

Cuboidal or polyhedral, abundant lipid droplets, lightly stained cytosol, abundant smooth ER

17
Q

What is produced in the zona fasciculata?

A

Glucocorticoids

-cortisol and hydrocortisone

18
Q

Where are glucocorticoids produced?

A

Zona fasciculata

19
Q

Where are mineralocorticoids produced?

A

Zona glomerulosa

20
Q

Where are sex steroids produced

A

Zona reticularis

21
Q

What NT acts on chromaffin cells

A

Ach

22
Q

Medulla cell characteristics

A
Columnar, ovoid, polyhedral
Large, pale
Non regenerative
Prominent golgi/RER
Secretory granules