Pancreas etc Flashcards
Why might you see increased unconjugated bilirubin?
Haemolytic, sickle cell or pernicious anaemia
Transfusion reaction
Why might you see increased conjugated bilirubin?
Liver obstruction Bile duct obstruction Hepatitis Trauma to liver Cirrhosis
What would cause a rise in alpha-fetoprotein?
Tumor marker
Raised in liver and testicular cancer
What is pancreatin and when/how to take?
e.g. creon
CF, pancreatectomy, gastrctomy, chronic pancreatitis
Take with food
+ PPI/H2RA
A/Es of pancreatin?
Perioral/perianal irritation
N&V, abdo discomfort
Treatment for pancreatic Ca?
Gemcitabine, capecitabine
Pancreatic Ca management/Ix?
USS Ct for staging ERCP for biopsy / cytology EUS for seeing if PV/SMV invasion Chemotherapy Stenting / analgesia etc
Sodium overload investigation?
24h urine Na+
Sodium overload in renal failuretx?
Strict Na+/H2O restriction
Diuretics
Dialysis
Hyperkalaemia?
> 6 = increased risk of cardiac damage, arrythmias, death
Hyperkalaemia in renal failure tx?
Dextrose
Calcium rizonium
Salbutamol
Anaemia in renal failure due to?
Low PaO2 usually results in kidney EPO and therefore increased haematopoiesis
In renal failure, less nephrons so less EPO, less haematopoiesis, less Hb and anaemia
Tx for anaemia in renal failure?
EPO + iron IVI