Pancreas etc Flashcards

1
Q

Why might you see increased unconjugated bilirubin?

A

Haemolytic, sickle cell or pernicious anaemia

Transfusion reaction

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2
Q

Why might you see increased conjugated bilirubin?

A
Liver obstruction
Bile duct obstruction
Hepatitis
Trauma to liver
Cirrhosis
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3
Q

What would cause a rise in alpha-fetoprotein?

A

Tumor marker

Raised in liver and testicular cancer

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4
Q

What is pancreatin and when/how to take?

A

e.g. creon

CF, pancreatectomy, gastrctomy, chronic pancreatitis

Take with food

+ PPI/H2RA

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5
Q

A/Es of pancreatin?

A

Perioral/perianal irritation

N&V, abdo discomfort

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6
Q

Treatment for pancreatic Ca?

A

Gemcitabine, capecitabine

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7
Q

Pancreatic Ca management/Ix?

A
USS
Ct for staging
ERCP for biopsy / cytology
EUS for seeing if PV/SMV invasion
Chemotherapy
Stenting / analgesia etc
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8
Q

Sodium overload investigation?

A

24h urine Na+

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9
Q

Sodium overload in renal failuretx?

A

Strict Na+/H2O restriction
Diuretics
Dialysis

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10
Q

Hyperkalaemia?

A

> 6 = increased risk of cardiac damage, arrythmias, death

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11
Q

Hyperkalaemia in renal failure tx?

A

Dextrose
Calcium rizonium
Salbutamol

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12
Q

Anaemia in renal failure due to?

A

Low PaO2 usually results in kidney EPO and therefore increased haematopoiesis

In renal failure, less nephrons so less EPO, less haematopoiesis, less Hb and anaemia

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13
Q

Tx for anaemia in renal failure?

A

EPO + iron IVI

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